Bateman, Jack - Bowdoin College - Department of Biology

个人简介

My lab studies how chromosomes are organized within the three-dimensional space of the nucleus, and, in particular, how physical interactions between chromosomes can influence gene expression. We focus on Drosophila melanogaster in part because of the amazing genetic tools available, and in part because there is extensive pairing between homologous chromosomes in this system, providing us with a simple model to study interchromosomal interactions. Some of our projects branch out into the development of new genetic technologies and resources for the Drosophila research community. Postdoctoral Fellow, Department of Genetics, Harvard Medical School Ph.D. in Cellular and Developmental Biology, Department of Cell Biology, Harvard Medical School B.Sc. in Biology, Dalhousie University

研究领域

My teaching and research interests are centered within the field of evolutionary genetics. Current research projects include: testing models of antagonistic coevolution by studying populations of nematodes that have evolved under different mating conditions; developing transgenic technology in fruit flies in order to test hypotheses about the function of non-coding DNA (collaboration with Jack Bateman); and using mitochondrial genome sequences to investigate the coevolutionary relationships between follicle mites and their mammalian hosts.

近期论文

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Blick, A.J.*1, Mayer-Hirshfeld, I.* 1, Malibiran, B.R.*, Cooper, M.A.*, Martino, P.A.*, Johnson, J.E., and Bateman, J.R.. 2016. The Capacity to Act in Trans Varies Among Drosophila Enhancers. Genetics 203: 203-218. (1Equal contribution) Bing, X., Rzezniczak, T.Z., Bateman, J.R., and Merritt, T.J.S. 2014. Transvection-based gene regulation in Drosophila is a complex and plastic trait. G3: Genes, Genomes, Genetics 4: 2175-2187. Bateman, J.R., Palopoli, M.F., Dale, S.T.*, Stauffer, J.E.*, Shah, A.L.*, Johnson, J.E., Walsh, C.W.*, Flaten, H.*, Parsons, C.M.* 2013. Captured segment exchange: A strategy for custom engineering large genomic regions in Drosophila melanogaster. Genetics 193: 421-430. Bateman, J.R., Johnson, J.E., Locke, M.N.* 2012. Comparing enhancer action in cis and in trans. Genetics 191: 1143-1155. Bateman, J.R.,1 Larschan, E.,1 D’Souza, R., Marshall, L.S.*, Dempsey, K.E.*, Johnson, J.E., Mellone, B.G., and Kuroda, M.I. 2012. A genome-wide screen identifies genes that affect somatic homolog pairing in Drosophila. G3: Genes, Genomes, Genetics. 2: 731-740. (1equal contribution) Sun, F.F.*, Johnson, J.E., Zeidler, M.P., and Bateman, J.R. 2012. Simplified insertion of transgenes onto balancer chromosomes via recombinase-mediated cassette exhange. G3: Genes, Genomes, Genetics. 2: 551-553.