林志芬 - 同济大学 - 环境科学与工程学院

个人简介

教育和工作经历 1999.03-2002.03 博士，南京大学环境学院环境化学专业 2002.01-2003,12 副研究员，中科院南海海洋研究所海洋环境与生态研究室 2004.01- 2005,03 研究员，中科院南海海洋研究所海洋环境与生态研究室 2005.03-2008,12 研究员/博导，中科院南海海洋研究所海洋环境与生态研究室 2009.01-至今教授/博导，同济大学环境科学与工程学院环境科学系上海市化学品分析、风险评估与污染控制重点实验室常务副主任；同济大学环境化学品暴露与风险研究所所长

研究领域

Hormesis信号分子机制及其应用研究混合化合物联合生物效应预测与机制中西药品环境效应与资源化研究分子对接与定量结构-活性相关（QSAR）新模型

近期论文

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Dali Wang , Edward J. Calabrese , Baoling Lian , Zhifen Lin* , Vittorio Calabrese. Hormesis as a mechanistic approach to understanding herbal treatments in traditional Chinese medicine，Pharmacology and Therapeutics, 2018，184，42–50 Haoyu Sun, Hongming Ge, Min Zheng, Zhifen Lin *, Ying Liu, Mechanistic Investigation of the Time-dependent Cross Phenomenon between Concentration-response Curves of Chemical Mixtures and CA-IA Curves: A Case Study of the Effect of Sulfonamides and Erythromycin on Escherichia coli, Scientific reports | 6:33718 | DOI: 10.1038/srep33718 Ting Wang, Yuewei Liu, Dali Wang, Zhifen Lin*, The joint effects of sulfonamides and Quorum sensing Inhibitors on vibrio fischeri: Differences between the acute and chronic mixed toxicity mechanisms. Journal of hazardous material, 2016，310，56-67 Min Zheng, Zhifeng Yao, Zhifen Lin*, Shuxia Fang，Miao Tang, Chunlei Song, Ying Liu. Novel Approach for Predicting the Joint Effects Based on the Enzyme-catalyzed Kinetics. Journal of hazardous material. 2016，307，359-367 Dali wang ,Zhifen Lin*, Ting Wang, Mengnan Qin , Shourong Zheng , Wei Lu Where Does the Toxicity of Metal Oxide Nanoparticles Come From: the Nanoparticles, the Ions, or a Combination of Both? Journal of hazardous material. 2016，308，328-334 Hongming Ge; ZhifenLin*; Ya Gao; Zhifeng Yao; DaqiangYin，The Balance between Weeding Effect and Environmental Risk：A Case Study of Joint Effects with Triazine and Phenylurea Herbicides on Photosynthesis & Non-Photosynthesis Organisms, Aquatic Toxicology, 2014,150,165-174 Ziqin Deng, Zhifen Lin*, et al., A novel model of hormesis and its toxicity mechanism based on quorum sensing: a case study on the toxicity of sulfonamides to Photobacterium phosphoreum Environmental Science& Technology 2012,46, 7746-7754. Dayong Tian •Zhifen Lin*，et al., The atomic charges of individual reactive chemicals in mixtures determine their joint effects: an example of cyanogenic toxicants and aldehydes，Environmental Toxicology and Chemistry, 2012, 31 (2): 270–278 Zhifen Lin*, et al., Development of QSARs for predicting the joint effect between cyanogenic toxicants and aldehydes, Chemical Research in Toxicology. 2003, 16(10), 1365-1371 Zhifen Lin*, et al., Use of partition coefficients to predict mixture toxicity for improving water quality criteria. Water Research. 2003, 37(9), 2223-2227