个人简介
教育背景 博士 1998.09-2012.06 山东大学 微生物学 硕士 1989.09-1992.06 山东师范大学 植物学 学士 1985.09-1989.06 山东师范大学 生物学 工作经历 起止时间 单位名称 专业技术职务 1992.07-1998.09 山东省农业科学院棉花研究中心 助理研究员 1998.10-2002.08 山东大学微生物技术国家实验室 讲师 2002.09-2004.08 山东大学微生物技术国家实验室 副教授 2004.09-至今 山东大学微生物技术国家实验室 教授 2007-至今 山东大学微生物技术国家实验室 博士生导师
研究领域
(1)海洋极端微生物独特的生命特征与环境适应机制及结构基础; (3)海洋微生物酶学与重要海洋有机碳、氮、磷、硫生物地球化学循环的分子机制; (3)海洋微生物资源开发与利用技术。
近期论文
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1. Fei Xu, Fang Dong, Peng Wang, Hai-Yan Cao, Chun-Yang Li, Ping-Yi Li, Xiu-Hua Pang, Yu-Zhong Zhang,Xiu-Lan Chen*, Novel Molecular Insights into the Catalytic Mechanism of Marine Bacterial Alginate Lyase AlyGC from Polysaccharide Lyase Family 6.J Biol Chem.March 17, 2017, 292, 4457-4468. 2. Ping-Yi Li#, Qiong-Qiong Yao#, Peng Wang, Yi Zhang, Yue Li, Yan-Qi Zhang, Jie Hao, Bai-Cheng Zhou,Xiu-Lan Chen*, Mei Shi, Yu-Zhong Zhang, Xi-Ying Zhang*, A Novel Subfamily Esterase with a Homoserine Transacetylase-like Fold but No Transferase Activity.Applied and Environmental Microbiology, May 2017 Volume 83 Issue 9 e00131-17. 3. Ping-Yi Li#, Yi Zhang#, Bin-Bin Xie*, Yan-Qi Zhang, Jie Hao, Yue Wang, Peng Wang, Chun-Yang Li, Qi-Long Qin, Xi-Ying Zhang, Hai-Nan Su, Mei Shi, Yu-Zhong Zhang,Xiu-Lan Chen*, Structural and Mechanistic Insights intothe Improvement of the Halotolerance of a Marine Microbial Esterase by Increasing Intra- and Interdomain Hydrophobic Interactions.Applied and Environmental Microbiology, 83:e01286-17. 4.Fei Xu, Peng Wang, Yu-Zhong Zhang,Xiu-Lan Chen*, Diversity of Three-Dimensional Structures and Catalytic Mechanisms of Alginate Lyases.Appl Environ Microbiol, 84:e02040-17. 5.Ang Liu, Yang Yu, Qi Sheng, Xiao-Yu Zheng, Jin-Yu Yang, Ping-Yi Li, Mei Shi, Bai-Cheng Zhou, Yu-Zhong Zhang,Xiu-Lan Chen*(2016)Identification of four kinds of 2′, 3′-cNMPs inEscherichia coliand a simple and efficient method for their simultaneous preparation. ACS Chemical Biology11: 2414-2419. 6. Ping-Yi Li,Xiu-Lan Chen, Peng Ji, Chun-Yang Li, Peng Wang, Yi Zhang, Bin-Bin Xie, Qi-Long Qin, Hai-Nan Su, Bai-Cheng Zhou, Yu-Zhong Zhang, and Xi-Ying Zhang*,Interdomain Hydrophobic Interactions Modulate the Thermostability of Microbial Esterases from the Hormone-Sensitive Lipase Family.J. Biol. Chem.2015 290: 11188-11198. 7. Zi-Chao Yu,Xiu-Lan Chen,Qing-Tao Shen, Dian-Li Zhao, Bai-Lu Tang, Hai-Nan Su, Zhao-Yu Wu, Qi-Long Qin, Bin-Bin Xie, Xi-Ying Zhang, Yong Yu, Bai-Cheng Zhou, Bo Chen and Yu-Zhong Zhang* Filamentous phages prevalent inPseudoalteromonasspp. confer properties advantageous to host survival in Arctic sea ice,ISME Journal,2015 Mar 17;9:871-81. 8.Chun-Yang Li, Tian-Di Wei, Sheng-Hui Zhang,Xiu-Lan Chen,Xiang Gao, Peng Wang, Bin-Bin Xie, Hai-Nan Su, Qi-Long Qin, Xi-Ying Zhang, Juan Yu, Hong-Hai Zhang, Bai-Cheng Zhou, Gui-Peng Yang and Yu-Zhong Zhang*, Molecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide,Proc Natl Acad Sci U S A2014, 111(3):1026-1031. 9.Hui-Lin Zhao,Xiu-Lan Chen,Bin-Bin Xie,Ming-Yang Zhou,Xiang Gao,Xi-Ying Zhang,Bai-Cheng Zhou,Anthony S. WeissandYu-Zhong Zhang*, Elastolytic mechanism of a novel M23 metalloprotease pseudoalterin from deep-sea Pseudoalteromonas sp. CF6-2: cleaving not only glycyl bonds in the hydrophobic regions, but also peptide bonds in the hydrophilic regions involved in crosslinking,J Biol Chem.2012,;287(47):39710-20. 10. Guo-Yan Zhao, Ming-Yang Zhou, Hui-Lin Zhao,Xiu-Lan Chen*, Bin-Bin Xie, Xi-Ying Zhang, Hai-Lun He, Bai-Cheng Zhou, Yu-Zhong Zhang. Tenderization effect of cold-adapted collagenolytic protease MCP-01 on beef meat at low temperature and its mechanism.Food Chem.2012;134(4):1738-44.