个人简介
受教育经历 1999/09 – 2004/06,山东大学,生命科学学院,博士 1992/09 – 1996/06,山东大学,微生物学系,学士 工作经历 2014/01 – 至 今,禹城市人民政府挂职副市长 2013/09 – 至 今,山东大学,生命科学学院,博士生导师 2011/12 – 至 今,山东大学,生命科学学院,教授 2006/09 – 2011/12,山东大学,生命科学学院,副教授 2004/07 – 2006/09,山东大学,生命科学学院,讲师 1996/07 – 1999/09,济南科贝尔生物工程有限公司,助理工程师
研究领域
微生物生理生化及生物信息学 1.碳水化合物活性酶分子的理性设计 2.秸秆资源的生物转化与资源化利用 3.畜禽废弃物生物降解与资源转化利用
近期论文
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1) Xukai Jiang, Guanjun Chen, Lushan Wang*. Structural and dynamic evolution of the amphipathic N-terminus diversifies enzyme thermostability in the glycoside hydrolase family 12. Phys. Chem. Chem. Phys., 18: 21340-21350, 2016 2) Weili Gong, Huaiqiang Zhang, Li Tian, Shijia Liu, Xiuyun Wu, Fuli Li, Lushan Wang*. Determination of the modes of action and synergies of xylanases by analysis of xylooligosaccharide profiles over time using fluorescence-assisted carbohydrate electrophoresis, Electrophoresis, 37: 1640–1650, 2016 3) Li Tian, Shijia Liu, Shuai Wang, Lushan Wang*. Ligand-binding specificity and promiscuity of the main lignocellulolytic enzyme families as revealed by active-site architecture analysis Scientific Reports, 6:23605, 2016. 4) Lili Zhang, Huaiqiang Zhang, Zhiheng Wang, Guanjun Chen, Lushan Wang*. Dynamic changes of the dominant functioning microbial community in the compost of a 90-m3 aerobic solid state fermentor revealed by integrated meta-omics. Bioresource Technology, 203: 1–10, 2016. 5) Xiaomei Zhang, Shuai Wang, Xiuyun Wu, Shijia Liu, Dandan Li, Hao Xu, Peiji Gao, Guanjun Chen, Lushan Wang*. Subsite-specific contributions of different aromatic residues in the active site architecture of glycoside hydrolase family 12. Scientific Reports 5: 18357 2015. 6) Shijia Liu, Shangjin Shao, Linlin Li, Zhi Cheng, Li Tian, Peiji Gao, Lushan Wang*. Substrate-binding specificity of chitinase and chitosanase as revealed by active-site architecture analysis. Carbohydrate Research, 418(12):50-56, 2015 7) Lili Zhang, Haixia Ma, Huaiqiang Zhang, Luying Xun, Guanjun Chen, Lushan Wang*. Thermomyces lanuginosus is The Dominant Fungus in Maize Straw Composts. Bioresource Technology, 197:266–275,2015 8) Weili Gong, Huaiqiang Zhang, Shijia Liu, Lili Zhang, Peiji Gao, Guanjun Chen, Lushan Wang*. Comparative Secretome Analysis of Aspergillus niger, Trichoderma reesei, and Penicillium oxalicum During Solid-State Fermentation. Applied Biochemistry and Biotechnology, 177(6), 1252-1271, 2015 9) Qing Zhang, Xiaomei Zhang, Peipei Wang, Dandan Li, Guanjun Chen, Peiji Gao, Lushan Wang*. Determination of the action modes of cellulases from hydrolytic profiles over a time course using fluorescence-assisted carbohydrate electrophoresis, Electrophoresis, 36: 910–917,2015 10) Xiaomei Zhang, Ning Liu, Fan Yang, Jinghua Li, Lushan Wang*, Guanjun Chen and Peiji Gao. In Situ Demonstration and Quantitative Analysis of the Intrinsic Properties of Glycoside Hydrolases. Electrophoresis, 33(2):280-287, 2012 11) Jinghua Li,Lushan Wang*. Why Substituting The Asparagine At Position 35 In Bacillus Circulans Xylanase With An Aspartic Acid Remarkably Improves The Enzymatic Catalytic Activity? A Quantum Chemistry-Based Calculation Study. Polymer Degradation and Stability , 96:1009-1014, 2011. 12) Zheng Zhang, Jie Huang, Zengfang Wang, Lushan Wang* and Peiji Gao. Impact of indels on the flanking regions in structural domains. Molecular biology and evolution, 28(1):291–301,2011. 13) Jinghua Li, Likai Du, Lushan Wang*. Glycosidic-Bond Hydrolysis Mechanism Catalyzed by Cellulase Cel7A from Trichoderma reesei: A Comprehensive Theoretical Study by Performing MD, QM, and QM/MM Calculations. The Journal of Physical Chemistry B, 114:15261–15268, 2010. 14) Lu-shan Wang, Yu-zhong Zhang, Pei-ji Gao*. Dongxia Shi, Hongwen Liu, Hongjun Gao, Changes in the structural properties and rate of hydrolysis of cotton fibres during extended enzymatic hydrolysis. Biotechnol. Bioeng. 93: 443-456, 2006.