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个人简介

起止时间 单位名称 专业技术职务 2012/07−2017/07 耶鲁大学 博士后 2017/07−至今 山东大学 教授

研究领域

1. 病原微生物致病的分子机制 2. 肠道病原微生物、肠道菌群以及宿主之间相互作用的分子机制

近期论文

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(1)Xiang Gao,Lingquan Deng,Gabrielle Stack,Hai Yu,Xi Chen,Yuko Naito-Matsui,Ajit VarkiandJorge E. Galán*(2017)Evolution of host adaptation in the Salmonella typhoid toxin. Nature Microbiology 12, 1592-1599. (2)Lingquan Deng#,Jeongmin Song#,Xiang Gao#, Jiawei Wang, Hai Yu, Xi Chen, Nissi Varki, Yuko Naito-Matsui, Jorge Galan*and Ajit Varki*(2014) Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi. Cell 159(6):1290-9. (3)Jeongmin Song#,Xiang Gao# &Jorge E. Galán*(2013) Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature 499(7458):350-4 (4)Xiang Gao#, Lijun Zhou#, Xuyao Jiao, Feiran Lu, Chuangye Yan, Xin Zeng, Jiawei Wang & Yigong Shi*(2010) Mechanism of substrate recognition and transport by an amino acid antiporter. Nature 463, 828-832. (5)Xiang Gao#, Feiran Lu#, Lijun Zhou#, Shangyu Dang, Linfeng Sun, Xiaochun Li, Jiawei Wang and Yigong Shi*(2009) Structure and Mechanism of an Amino Acid Antiporter. Science 324, 1565-1568. (6)Casey Fowler, Shu-Jung Chang, Xiang Gao, Tobias Geiger, Gabrielle Stack andJorge E. Galán*(2017) Emerging insights into the biology of typhoid toxin. Curr Opin Microbiol 35:70-77 (invited review paper). (7)Stefania Spanò#,Xiang Gao#,Sebastian Hannemann#,María Lara-TejeroandJorge E. Galán*(2015) A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP. Cell Host & Microbe 19(2):216-26.

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