邵明 - 山东大学 - 生命科学学院

个人简介

教育背景博士 2005.9-2010.7 山东大学发育生物学本科 2001.9-2005.7 山东大学生物科学工作经历 2010.10-2011.10 Université Pierre et Marie Curie，UPMC 博士后 2018.9-今山东大学副教授 2010.7-2018.8 山东大学讲师 2018.7 入选山东大学青年学者未来计划

研究领域

1. 脊椎动物背腹轴形成母源调控的分子机制 2. 脊椎动物早期形态发生运动的分子机理 3. 人类遗传病相关基因的功能和分子机理

近期论文

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Xing, Y.1, Cheng, X., Li, Y., Zhang, C., Saquet, A., Liu, Y., Shao, M.#, Shi D.# (2018) Mutational analysis of dishevelled genes in zebrafish reveals distinct functions in embryonic patterning and gastrulation cell movements. PLoS Genet. 14(8):e1007551. doi: 10.1371/journal.pgen.1007551. Li, Y.1, Zhang, C., Zhang, Y., Lin, S., Shi D., Shao M.# (2018) Highly efficient genome editing using oocyte-specific zcas9 transgenic zebrafish. J. Genet. Genomics. In Press. doi: 10.1016/j.jgg.2018.05.004. Cheng, X.1, Shao, M.1, Li, J.1, Wang, Y., Qi, J., Xu, Z.#, Shi D.# (2017) Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish. Nat Commun. 8(1):1353. doi: 10.1038/s41467-017-01552-x. Shao, M.1, Wang, M., Liu, Y., Ge, Y., Zhang, Y., Shi, D.# (2017) Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish. Development. 144(18):3361-3374. doi: 10.1242/dev.152553. Shao, M.1#, Cheng, X., Liu, Y., Li, J., Shi, D.# (2017) Transplantation of Zebrafish Cells by Conventional Pneumatic Microinjector. Zebrafish. doi: 10.1089/zeb.2017.1495. Shao, M.1, Lin, Y., Liu, Z., Zhang, Y., Wang, L., Liu, C., & Zhang, H.# (2012). GSK-3 activity is critical for the orientation of the cortical microtubules and the dorsoventral axis determination in zebrafish embryos. PLoS One, 7(5), e36655. doi: 10.1371/journal.pone.0036655 Zhang, Y.1,Shao, M.1, Wang, L., Liu, Z., Gao, M., Liu, C., & Zhang, H.# (2010). Ethanol exposure affects cell movement during gastrulation and induces split axes in zebrafish embryos. Int J Dev Neurosci, 28(4), 283-288. doi: 10.1016/j.ijdevneu.2010.04.001 Shao, M.1, Liu, Z. Z., Wang, C. D., Li, H. Y., Carron, C., Zhang, H. W.#, & Shi, D. L.# (2009). Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos. Development, 136(12), 2121-2131. doi: 10.1242/dev.032649