徐志刚 - 山东大学 - 生命科学学院

个人简介

教育背景本科 1995.09 - 1998.07 烟台大学生物化学博士 1998.09 - 2004.01 复旦大学遗传学工作经历起止时间单位名称专业技术职务 2004.01–2004.12 中国国家人类基因组南方研究中心科研人员 2005.01–2005.09 美国哈佛大学医学院博士后 2005.10–2009.05 美国斯坦福大学医学院博士后 2009.05–现在山东大学生命科学学院教授

研究领域

1. 耳聋发生机制 2. 听纤毛发育及维持机制 3. 听觉转导分子机制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Wang Y, Li J, Yao X, Li W, Du H, Tang M, Xiong W, Chai R*, Xu Z*. Loss of CIB2 causes profound hearing loss and abolishes mechanoelectrical transduction in mice. Front. Mol. Neurosci., 2017, 10: 401. 2.Cheng X, Shao M, Li J, Wang Y, Qi J, Xu Z*, Shi D*. Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish. Nat. Commun. 2017, 8: 1353. 3.Liu Y, Nie H, Liu C, Zhai X, Sang Q, Wang Y, Shi D, Wang L*, Xu Z*. Angulin proteins ILDR1 and ILDR2 regulate alternative pre-mRNA splicing through binding to splicing factors TRA2A, TRA2B, or SRSF1. Sci Rep. 2017 Aug 7;7(1):7466. 4.Liu C, Zhai X, Zhao B, Wang Y, Xu Z*. Cyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulation. Sci Rep. 2017 Jan 23. 7:40979. 5.Liu C, Zhai X, Du H, Cao Y, Cao H, Wang Y, Yu X, Gao J, Xu Z*. Sorting nexin 9 (SNX9) is not essential for development and auditory function in mice. Oncotarget. 2016 Sep 15. 7(42): 68921-32. 6.Hu QX, Dong JH, Du HB, Zhang DL, Ren HZ, Ma ML, Cai Y, Zhao TC, Yin XL, Yu X, Xue T, Xu ZG*, Sun JP*. Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein. J Biol Chem. 2014 Aug 29;289(35):24215-25. 7.Cao H, Yin X, Cao Y, Jin Y, Wang S, Kong Y, Chen Y, Gao J, Heller S, Xu Z*. FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS One. 2013; 8(2): e56516. 8.Xu Z, Ricci AJ, Heller S. Rethinking how hearing happens. Neuron. 2009; 62(3):305-7. 9.Xu Z, Peng AW, Oshima K, Heller S. MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23. J Neurosci. 2008; 28(44):11269-76. 10.Xu ZG, Du JJ, Zhang X, Cheng ZH, Ma ZZ, Xiao HS, Yu L, Wang ZQ, Li YY, Huo KK, Han ZG. A novel liver-specific zona pellucida domain containing protein that is expressed rarely in hepatocellular carcinoma. Hepatology. 2003;38(3):735-44.