王金星 - 山东大学 - 生命科学学院

个人简介

教育背景博士 1995.09-1998.06 南京师范大学动物学硕士 1982.02-1984.12 山东大学动物学本科 1978.02-1981.01 山东师范大学生物学工作经历 1997.9-至今　　山东大学教授 1992.09-1997.07 山东大学副教授 1987.09-1992.07 山东大学讲师 1984.12-1987.07 山东大学助教

研究领域

无脊椎动物先天免疫：近二十年来一直从事无脊椎动物先天免疫研究，研究工作包括病原的模式识别，信号转导途径和效应分子等。

近期论文

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15. Niu GJ, Wang S, Xu JD, Yang MC, Sun JJ, He ZH, Zhao XF, Wang JX*. The polymeric immunoglobulin receptor-like protein from Marsupenaeus japonicus is a receptor for white spot syndrome virus infection. PLoS Pathog. 2019 Feb 6;15(2):e1007558. 14. Niu GJ, Xu JD, Yuan WJ, Sun JJ, Yang MC, He ZH, Zhao XF, Wang JX*. Protein inhibitor of activated STAT (PIAS) negatively regulates the JAK/STAT pathway by inhibiting STAT phosphorylation and translocation. Front Immunol. 2018 Oct 26; 9:2392. 13. Xu JD, Diao MQ, Niu GJ, Wang XW, Zhao XF, Wang JX*. A small GTPase, RhoA, inhibits bacterial infection through integrin mediated phagocytosis in invertebrates. Front Immunol. 2018 Aug 30;9:1928. 12. Sun JJ, Lan JF, Zhao XF, Vasta GR, Wang JX*. Binding of a C-type lectin's coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection. PLoS Pathog. 2017 Sep 20;13(9):e1006626. 11. Wang XW*, Gao J, Xu YH, Xu JD, Fan ZX, Zhao XF, Wang JX*. Novel pattern recognition receptor protects shrimp by preventing bacterial colonization and promoting phagocytosis. J. Immunol. 2017 Apr 15;198(8):3045-3057 10. Xu JD, Jiang HS, Wei TD, Zhang KY, Wang XW, Zhao XF, Wang JX*. Interaction of the small GTPase Cdc42 with arginine kinase restricts white spot syndrome virus in shrimp. J. Virol. 2017 March; 91(5):e01916-16. This article was chosen by editors as a spotlight article: http://jvi.asm.org/content/91/5/e00017-17.full 9. Yang MC, Shi XZ, Yang HT, Sun JJ, Xu L, Wang XW, Zhao XF, Wang JX*. Scavenger receptor C mediates phagocytosis of white spot syndrome virus and restricts virus proliferation in shrimp. PLoS Pathog. 2016 Dec 27; 12(12):e1006127. 8. Sun JJ, Lan JF, Shi XZ, Yang MC, Niu GJ, Ding D, Zhao XF, Yu XQ, Wang JX*.β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional Activity. J. Biol. Chem. 2016 Apr 1;291(14):7488-504. 7. Wang XW, Xu YH, Xu JD, Zhao XF, Wang JX*.Collaboration between a soluble C-type lectin and calreticulin facilitates white spot syndrome virus infection in shrimp. J. Immunol. 2014 Sep 1;193(5):2106-17. 6. Wang XW, Xu JD, Zhao XF, Vasta GR, Wang JX*. A shrimp C-type lectin inhibits proliferation of the hemolymph microbiota by maintaining the expression of antimicrobial peptides. J. Biol. Chem. 2014 Apr 25; 289(17):11779-90. 5. Wang XW, Zhao XF, Wang JX*. C-type lectin binds to β-integrin to promote hemocytic phagocytosis in an invertebrate. J. Biol. Chem. 2014 Jan 24; 289(4):2405- 2414. 4. Lan JF, Li XC, Sun JJ, Gong J, Wang XW, Shi XZ, Shi LJ, WengYD Zhao XF, Wang J-X* Prohibitin interacts with envelope proteins of white spot syndrome virus and prevents infection in red swamp crayfish Procambarus clarkii. J. Virol. 2013 Dec; 87(23):12756-65. 3. Chen AJ, Gao L, Wang XW, Zhao XF, Wang JX*. SUMO conjugating enzyme E2 UBC9 mediates viral immediate-early protein SUMOylation in crayfish to facilitate reproduction of white spot syndrome virus. J. Virol. 2013 Jan; 87(1):636-47. 2. Chen AJ Wang S Zhao X-F, Yu XQ, Wang JX*. E2 enzyme from Chinese White Shrimp inhibits replication of white spot syndrome virus and ubiquitinates its RING domain proteins. J. Virol. 2011 Aug; 85(16):8069-79. 1. Wang S , Liu N, Chen AJ, Zhao XF, Wang JX*. TRBP homologue interacts with eukaryotic initiation factor 6 (eIF6) in Fenneropenaeus chinensis. J. Immunol. 2009 May 1; 182(9):5250-5258.