冯力骏 - 山东大学 - 生命科学学院

个人简介

教育背景博士 1995-2000 纽约州立大学布法罗分校分子和细胞生物学本科 1989-1993 山东大学生物化学工作经历 2000-2005 爱因斯坦医学院博后 2005-- 山东大学教授

研究领域

1.利用Hermansky-Pudlak Syndrome （HPS）小鼠模型--pale ear(ep), pearl (pe) 和双突变（ep/pe）研究HPS的致病机制，为临床治疗提供线索。 2.利用CAS9技术大规模突变斑马鱼生殖发育相关基因，寻找人类生殖异常相关基因，研究动物生殖器官的发育和调控机制，为临床不孕不育症的诊断治疗提供线索。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.The Ap3b1 gene regulates the ocular melanosome biogenesis and tyrosinase distribution differently from the Hps1 gene. Jing R, Dong X, Li K, Yan J, Chen X,Feng L. Exp Eye Res. 2014 Aug 24;128C:57-66. doi: 10.1016/j.exer.2014.08.010. [Epub ahead of print] 2.Two distinct phenotypes in pigmented cells of different embryonic origins in eyes of pale ear mice. Jing R, Dong X, Li K, Zhang J, Yan J,Feng L. Exp Eye Res. 2013 Dec 17;119C:35-43. doi: 10.1016/j.exer.2013.12.007. [Epub ahead of print] 3.Comparative genomic and phylogenetic analyses of the intelectin gene family: implications for their origin and evolution. Yan J, Xu L, Zhang Y, Zhang C, Zhang C, Zhao F,Feng L. Dev Comp Immunol. 2013 Oct;41(2):189-99. doi: 10.1016/j.dci.2013.04.016. Epub 2013 Apr 30. 4.Identification and primary immune characteristics of an amphioxus akirin homolog. Yan J, Dong X, Kong Y, Zhang Y, Jing R,Feng L. Fish Shellfish Immunol. 2013 Aug;35(2):564-71. doi:10.1016/j.fsi.2013.05.020. Epub 2013 May 31. 5.Characterization and comparative analyses of two amphioxus intelectins involved in the innate immune response. Yan J, Zhang C, Zhang Y, Li K, Xu L, Guo L, Kong Y,Feng L.Fish Shellfish Immunol. 2013 May;34(5):1139-46. doi: 10.1016/j.fsi.2013.01.017. Epub 2013 Feb 18. 6.Identification of an amphioxus intelectin homolog that preferably agglutinates gram-positive over gram-negative bacteria likely due to different binding capacity to LPS and PGN. Yan J, Wang J, Zhao Y, Zhang J, Bai C, Zhang C, Zhang C, Li K, Zhang H, Du X,Feng L.Fish Shellfish Immunol. 2012 Jul;33(1):11-20. doi: 10.1016/j.fsi.2012.03.023. Epub 2012 Mar 24. 7.Identification and characterization of an amphioxus matrix metalloproteinase homolog BbMMPL2 responding to bacteria challenge. Zhang Y, Zhang H, Kong Y,Feng L. Dev Comp Immunol. 2012 Jul;37(3-4):371-80. doi: 10.1016/j.dci.2012.02.015. Epub 2012 Mar 19. 8.Distinct gene structure and expression pattern of Smad nuclear interacting protein 1 in amphioxus and zebrafish. Kong W, Yang Y,Feng L, Zhang Y. Acta Histochem. 2012 Jul;114(4):386-91. doi: 10.1016/j.acthis.2011.07.007. Epub 2011 Aug 9. 9.Evaluation of the cytotoxicity of a two photon absorbing fluorescence compound on human HepG2 cells and its application to tracking human hepatic cancer cells in mice. Du XM, Yan Y, Bai ZL, Zhang JP, Wang Z, Liu LL,Feng LJ. Biotech Histochem. 2010 Apr;85(2):107-13. doi:10.1080/10520290903149588. 10.Phylogenetic analysis and expression pattern of the AmphiCaBP-like gene from amphioxus, encoding a novel member of the calmodulin-like subfamily. Li B, Lin Y, Zhang W, Shao M, Bian Y, Huang S,Feng L, Zhang H. DNA Seq. 2007 Jun;18(3):228-34.