个人简介
教育经历 1996.9~2000.7,山东大学,生物科学学士; 2000.9~2008.1, 北京大学植物分子生物学与蛋白质工程国家重点实验室,植物学博士。 研究经历 2008.4~2009.4, Postdoctoral Researcher, Bioanalytical Chemistry, Department of Chemistry, University of Waterloo, Canada 2009.8~2011.12, Postdoctoral Researcher, Cell Biology and Protein Chemistry, Department of Chemistry, University of Kansas, USA 2012.1~2012.5, Research Associate, Cell Biology and Protein Chemistry, Department of Chemistry, University of Kansas, USA 2012/06至今,山东大学,国家糖工程技术研究中心,讲师
研究领域
细胞外基质和肿瘤细胞微环境研究、糖苷酶基因克隆表达及分子改造及性质研究、 酶的固定化技术及应用等。
近期论文
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1. Li Xu, Dongxue Wang, Lili Lu, Lan Jin, Jiawei Liu, Deyong Song, Zhongwu Guo, Min XiaoPurification, cloning, characterization, and N-glycosylation analysis of a novel β-fructosidase from Aspergillus oryzae FS4 synthesizing levan and neolevan-type fructooligosaccharides. PLoS ONE (2014) 9(12):e114793. 2. Li Xu, Eden P. Go, Joel Finney, HeeJung Moon, Mason Lantz, Kathryn Rebecchi, Heather Desaire and Minae Mure、Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from drosophila S2 cells, Journal of Biological Chemistry (2013) 288, 5357-5363 3. Li Xu, Ye Wang, Lijiang Wang, Yin Gao, Chengcai An. TYchi, a novel chitinase with ribosome-inactivating and anti-tumor activities. Frontiers in Bioscience (2008) 13, 3127–3135. 4. Li Xu, Lijiang Wang, Tao Liu, Wanqiang Qian, Yin Gao, Chengcai An. Triton, a novel family of miniature inverted-repeat transposable elements (MITEs) in Trichosanthes kirilowii Maximowicz and its effect on gene regulation. Biochemical and Biophysical Research Communications (2007) 364, 668–674. 5. Hee-Jung Moon, Joel Finney, Li Xu, David Moore, Danny R. Welch, and Minae Mure. MCF-7 Cells Expressing Nuclear Associated Lysyl Oxidase-like 2 (LOXL2) Exhibit an Epithelial-to-Mesenchymal Transition (EMT) Phenotype and Are Highly Invasive in Vitro. Journal of Biological Chemistry (2013) 288 30000–30008 6.Kathryn R. Rebecchi, Eden P. Go, Li Xu, Carrie L. Woodin, Minae Mure, and Heather Desaire. A general protease digestion procedure for optimal protein sequence coverage and post-translational modifications analysis of recombinant glycoproteins: application to the characterization of human lysyl oxidase-like 2 glycosylation. Analytical Chemistry (2011) 83, 8484–8491 7. Zhiyong Chen, Li Xu, Yuan Liang, Meiping Zhao. pH-Sensitive Water-Soluble Nanospheric Imprinted Hydrogels Prepared as Horseradish Peroxidase Mimetic Enzymes. Advanced Materials (2010) 22, 1488–1492. 8. Zhiyong Chen, Li Xu, Yuan Liang, Jianbin Wang, Meiping Zhao, Yuanzong Li. Polyethylene glycol diacrylate-based supermacroporous monolithic cryogel as high-performance liquid chromatography stationary phase for protein and polymeric nanoparticle separation. Journal of Chromatography A (2008) 1182, 128-131. 9. Zhiyong Chen, Zhendong Hua, Li Xu, Yong Huang, Meiping Zhao, Yuanzong Li. Protein-responsive imprinted polymers with specific shrinking and rebinding. Journalof Molecular Recognition (2008) 21, 71-77