个人简介

Education Postdoctoral Fellow: 2002-2004, Colorado State University Postdoctoral Fellow: 2002, Mississippi State University Ph.D. in Chemistry: 2001, Universidad Nacional de Córdoba, Argentina B.S. in Biochemistry: 1996, Universidad Nacional de Córdoba, Argentina Bio Dr. Garcia received his B.S. in Biochemistry and Ph.D. in Chemistry from the National University of Cordoba (Argentina) in 1996 and 2001, respectively. During that period of time, he was a TA for the Department of Physical Chemistry and taught several courses at the undergraduate and graduate level. From 2002 to 2004, he was a postdoctoral fellow at Mississippi State University and Colorado State University under the supervision of Dr. W. Wilson and Dr. Charles Henry, respectively. In September of 2004, he joined the faculty at The University of Texas at San Antonio as an Assistant Professor of Analytical Chemistry. He was promoted to Associate Professor with tenure in 2010 and to Professor in 2014. Currently, his group is focused on the study of interactions of proteins with nanostructured surfaces and their use in analytical chemistry. Additionally, he is developing microfluidic devices to monitor biologically active compounds. Dr. Garcia is engaged in various professional activities which provide opportunities to recruit graduate students and to inform the public about the chemistry program at The University of Texas at San Antonio. These include the presentation of seminars at colleges and universities in Texas, and the presentation of posters at national and international meetings. At present, Dr. Garcia directs the thesis research of three chemistry graduate students (Ph.D. program). Dr. Garcia also has a substantial research program with undergraduates students, which complements and supports the research of graduate students. The outcomes of the research activities have been presented and recognized at national and international scientific meetings and are regularly published in peer-refereed journals, all of which have students as coauthors. His research has received support from the NIH SCORE program, National Science Foundation, and the Office of Naval Research.

研究领域

Electrochemistr ;Interactiooproteinwitnanomaterial ;Microfluidideviceanmicrofabrication

Microchips are one of the most promising analytical platforms due to the great advantages with respect to conventional bench-top equipment. Microfluidic devices are able to offer custom design, high throughput, sensitivity, selectivity and portability. In order to achieve a real point-of-care measurement device, simple instrumentation has to be integrated to drive the injection and separation. Electrochemical detection (ECD) methods have been widely applied for the detection of bio-compounds because they are less susceptible to decreases in signal magnitude during miniaturization and are already portable and inexpensive. For these reasons, we are very interested in studying the design, operation and biological applications of microchips and capillary electrophoresis. In addition, we are also interested in the rational design of biosensors.

近期论文

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Adsorption of "Soft" and "Hard" Proteins onto OTCEs under the Influence of an External Electric Field Tomas E. Benavides, Daniel Torrente, Marcelo Marucho, and Carlos D. Garcia Langmuir (2015) - in press Protein Adsorption onto Nanomaterials for the Development of Biosensors and Analytical Devices: A Review Samir Bhakta, Elizabeth Evans, Tomas E. Benavides, and Carlos D. Garcia Analytica Chimica Acta (2015) - in press Acid-Responsive Nanospheres from an Asparagine-Derived Amphiphile Adelphe M. Mfuh, Mathew P.D. Mahindaratne, Audrey E. Yñigez-Gutierrez, Juan R. Ramos Dominguez, Jefferson T. Bedell II, Carlos D. Garcia, and George R. Negrete RSC Advances 5 (2015) 8585-8590 Modification of Paper-Based Microfluidic Devices with Silica Nanoparticles Elizabeth Evans, Ellen Flavia Moreira-Gabriel, Tomas E. Benavides, Wendell K.T. Coltro, and Carlos D. Garcia Analyst 139 (2014) 5560-5567 Adsorption and Catalytic Activity of Glucose Oxidase Accumulated on OTCE upon the Application of External Potential Tomas Benavidez, Daniel Torrente, Marcelo Marucho, and Carlos D. Garcia Journal of Colloid & Interface Science 435 (2014) 164–170 A Handheld Stamping Process to Fabricate Microfluidic Paper-Based Analytical Devices with Chemically Modified Surface for Clinical Assays Paulo de T. Garcia, Thiago M. G. Cardoso, Carlos D. Garcia, E. Carrilho, and Wendell K. T. Coltro RSC Advances 4 (2014) 37637–37644 Getting Started with Open-Source Hardware: Development and Control of Microfluidic Devices Eric Tavares da Costa, Maria F. Mora, Peter A. Willis, Claudimir L. do Lago, Hong Jiao, and Carlos D. Garcia Electrophoresis 35 (2014) 2370–2377 Fast and Versatile Fabrication of PMMA Microchip Electrophoretic Devices by Laser Engraving Ellen Flavia Moreira-Gabriel, Wendell Karlos Tomazelli-Coltro, and Carlos D. Garcia Electrophoresis 35 (2014) 2325–2332 Immobilization of Glucose Oxidase to Nanostructured Films of Polystyrene-block-poly(2-vinylpyridine) Samir A Bhakta, Tomas Benavidez, and Carlos D. Garcia Journal of Colloid & Interface Science 430 (2014) 351–356 Rational Selection of Substrates to Improve Color Intensity and Uniformity on Microfluidic Paper-Based Analytical Devices Elizabeth Evans, Ellen Flavia Moreira-Gabriel, Wendell Karlos Tomazelli-Coltro, Carlos D. Garcia Analyst 139 (2014) 2127-2132 Determination of Nitrite in Saliva Using Microfluidic Paper-Based Analytical Devices Samir A. Bhakta, Rubiane Borba, Mario Taba Jr, Carlos D. Garcia, and Emanuel Carrilho Analytica Chimica Acta 809 (2014) 117-122 Potential-Assisted Adsorption of Bovine Serum Albumin onto Optically-Transparent Carbon Electrodes Tomas E. Benavidez and Carlos D. Garcia Langmuir 29 (2013) 14154–14162 Simultaneous Solid Phase Extraction and Derivatization of Aliphatic Primary Amines Prior to Separation and UV-Absorbance Detection Jessica L. Felhofer, Karen Scida, Mark Penick, Peter Willis, and Carlos D. Garcia Talanta 115 (2013) 688-693 Spectroscopic and Electrochemical Characterization of Nanostructured Optically-Transparent Carbon Electrodes Tomas E. Benavidez and Carlos D. Garcia Electrophoresis 34 (2013) 1998-2006 Ultrathin Optically Transparent Carbon Electrodes Produced from Layers of Adsorbed Proteins Sarah Alharthi, Tomas E. Benavidez, and Carlos D. Garcia Langmuir 29 (2013) 3320-3327 Microfab-less Microfluidic Capillary Electrophoresis Devices Thiago P. Segato, Samir A. Bhakta, Matthew Gordon, Emanuel Carrilho, Peter A. Willis, Hong Jiao, and Carlos D. Garcia Analytical Methods 5 (2013) 1652-1657 Computational, Electrochemical, and Spectroscopic, Studies of Acetycholinesterase Covalently Attached to Carbon Nanotubes Murilo F. Cabral, Joseph D. Barrios, Érica M. Kataoka, Sergio A. S. Machado, Emanuel Carrilho, Carlos D. Garcia, and Arturo A. Ayon Colloids and Surfaces B: Biointerfaces 103 (2013) 624-629 Research Spotlight: The Next Big Thing is Actually Small Carlos D. Garcia Bioanalysis 4 (2012) 1717-1722 Unmanned Platform for Long-Range Remote Analysis of Volatile Compounds in Air Samples E. Tavares da Costa, C.A. Neves, G.M. Hotta, D.T. Rajh Vidal, M.F. Barros, A.A. Ayon, C.D. Garcia, C.L. do Lago Electrophoresis 33 (2012) 2650-2659 Implementation of a Field Programmable Gate Array for Wireless Control of a Lab-on-a-Robot David Valdez, Carlos D. Garcia, and Arturo A. Ayon Analog Integrated Circuits and Signal Processing 71 (2012) 29-38