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个人简介

Dr. Liu obtained his B.S. degree from the University of Science and Technology of China in Hefei, Anhui, China and his Ph.D. degree from the University of Texas Southwestern Medical Center in Dallas, Texas, USA. He is an Associate Professor at the University of New Orleans.

近期论文

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Farooq, M., Pracheil, T., Dong, Z., Xiao, F., and Z. Liu. 2013. Mitochondrial DNA Instability in Cells Lacking Aconitase Correlates with Iron Citrate Toxicity. Oxidative Medicine and Cellular Longevity 2013(493536): 1-10. Aco1_mtDNA_maintenance_iron_citrate_toxicity.pdf Zhang, F., T. Pracheil, J. Thornton, and Z. Liu. 2013. Adenosine Triphosphate (ATP) Is a Candidate Signaling Molecule in the Mitochondria-to-Nucleus Retrograde Response Pathway. Genes 4:86-100. ATP_Retrograde_Signal_Genes_2013.pdf. Pracheil, T., and Z. Liu. 2013. Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulum. J Biol Chem 288:16986-16997. Guaragnella, N., M. Zdralevic, P. Lattanzio, D. Marzulli, T. Pracheil, Z. Liu, S. Passarella, E. Marra, and S. Giannattasio. 2013. Yeast growth in raffinose results in resistance to acetic-acid induced programmed cell death mostly due to the activation of the mitochondrial retrograde pathway. Biochim Biophys Acta. Pracheil, T., Thornton, J., and Liu, Z. (2012) TORC2 Signaling Is Antagonized by Protein Phosphatase 2A and the Far Complex in Saccharomyces cerevisiae. Genetics Vol. 190, 1325-1339. Far_Complex_TOR_Signaling_2012_Genetics.pdf. Tumusiime, S., Zhang, C., Overstreet, M., and Liu, Z. (2011) Differential Regulation of Transcription Factors Stp1 and Stp2 in the Ssy1-Ptr3-Ssy5 Amino Acid Sensing Pathway. J Biol. Chem., 286(6):4620-31. SPS_Signaling_JBC_2011.pdf. Liu, Z.*, Thornton, J., Spirek, M., and Butow, R.A. (2008) Activation of the SPS amino acid-sensing pathway in Saccharomyces cerevisiae correlates with the phosphorylation state of a sensor component, Ptr3. Mol. Cell. Biol. 28(2):551-63. *, corresponding author. Ptr3_Phosphorylation_MCB_2008.pdf. Liu, Z. and Butow, R. A. (2006) Mitochondrial Retrograde Signaling. Annu. Rev. Genet. 40: 159-185. Giannattasio, S., Liu, Z., Thornton, J., and Butow, R. A. (2005) Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression. J. Bio. Chem. 280(52): 42528-35. Tor_Signaling_Retrograde_JBC_2005.pdf. Liu, Z., Spirek, M., Thornton, J., and Butow, R.A. (2005) A Novel Degron-mediated Degradation of the RTG Pathway Regulator, Mks1p, by SCFGrr1. Mol. Bio. Cell. Vol. 16, 4893–4904. Grr1_Mks1_2005_MBC.pdf. Ferreira Junior JR, Spirek M, Liu Z., Butow R. A. (2005) Interaction between Rtg2p and Mks1p in the regulation of the RTG pathway of Saccharomyces cerevisiae. Gene 354: 2-8. Liu, Z., Sekito, T., Spirek, M., Thornton, J. and Butow, R.A. (2003). Retrograde Signaling Is Regulated by the Dynamic Interaction between Rtg2p and Mks1p. Molecular Cell 12: 401-411. Rtg2_Mks1_MCell_2003.pdf. Liu, Z. and Butow, R.A. (2003). Signaling pathways from mitochondria to the nucleus. Handbook of Cell Signaling. Edited by Bradshaw, R. and Dennis, E. Elsevier Science. Yoon, S., Liu, Z., Eyobo, Y. and Orth, K. (2003) Yersinia effector YopJ inhibits yeast MAPK signaling pathways by an evolutionarily conserved mechanism. J. Bio. Chem. 278: 2131-2135. YopJ_MAP_Kinase_2003_JBC.pdf. Sekito, T., Liu, Z., Thornton, J., and Butow, R. A. (2002) RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to the formation of the yeast prion [URE3]. Mol. Bio. Cell 13: 795-804. Mks1_Retrograde_Signaling_2002.MBC.pdf. Liu, Z., Sekito, T., Epstein, C. B., and Butow, R. A. (2001) RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p. EMBO J. 20: 7209-7219. Lst8_Retrograde_Signaling_2001_EMBOJ.pdf. Liu, Z. and Butow, R.A. (1999) A transcriptional switch in the expression of yeast tricarboxylic acid cycle genes in response to a reduction or loss of respiratory function. Mol. Cell. Biol. 19: 6720-6728. Hap_Rtg_TCA_Cycle_Gene_Expression_1999_MCB.pdf Chelstowska, A.*, Liu, Z.*, Jia, Y., Amberg D., and Butow, R. A. (1999) Signaling between mitochondria and the nucleus regulates the expression of a new D-lactate dehydrogenase activity. Yeast 15: 1377-1391. * Equal authorship. DLD3_Retrograde_Target_1999_Yeast.pdf Li, L., Liu, Z., Mercer, B., Overbeek, P., and Olson, E. N. (1997) Evidence for serum response factor-mediated regulatory networks governing SM22a transcription in smooth, skeletal, and cardiac muscle cells. Dev. Biol. 187: 311-321. SRF_SM22_Alpha_1997_DB.pdf.

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