个人简介
B.S., University of Colorado Boulder, 2006
Ph.D., University of Colorado Boulder, 2011
研究领域
Genome Engineering, Metabolic Engineering, Biofuels, biosensors, sequence-function elucidation
近期论文
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Long CP, Au J, Sandoval NR, Gebreselassie NA, Antoniewicz MR. Enzyme I facilitates reverse flux from pyrubate to phosphoenolpyruvate in Escherichia coli. Nat Commun. 2017;8:14316
Sandoval NR, Papoutsakis ET: Engineering membrane and cell-wall programs for tolerance to toxic chemicals: Beyond solo genes. Curr Opin Microbiol 2016, 33:56-66.
CP Long, JE Gonzalez, NR Sandoval, MR Antoniewicz: Characterization of physiological responses to 22 gene knockouts in Escherichia coli central carbon metabolism, Metab eng, 37 (2016).
Cordova LT, Lu J, Cipolla RM, Sandoval NR, and Antoniewicz MR: Simultaneous utilization of glucose and xylose by an evolved Thermus thermophilus strain elucidated by 13C metabolic flux analysis and genome sequencing. Metab eng, 37 (2016) 63-71.
Sandoval NR, Venkataramanan KP, Groth TS, Papoutsakis ET: Genome sequencing identifies Spo0A inactivation in Clostridium pasteurianum as imparting enhanced tolerance to crude glycerol and increased growth-associated butanol production. Biotechnology for biofuels, 8 (2015) 227.
Gaida SM*, Sandoval NR*, Nicolaou SA, Chen Y, and Papoutsakis ET: Expression of heterologous sigma factors enables functional screening of metagenomic and heterologous genomic libraries Nat Comm 2015, 6:7045.
Whitaker WB, Sandoval NR, Bennett RK, and Papoutsakis ET: Synthetic methylotrophy: engineering the production of biofuels and chemicals based on the biology of aerobic methanol utilization. Curr Opin Biotechnol. (2015) 33:165–175.
Glebes TY, Sandoval NR, Gillis JH and Gill RT: Comparison of genome-wide selection strategies to identify furfural tolerance genes in Escherichia coli. Biotechnol Bioeng. (2015) 112:129-140.
Glebes TY, Sandoval NR, Reeder PJ, Schilling KD, Zhang M, Gill RT: Genome-wide mapping of furfural tolerance genes in Escherichia coli. PLoS One 9(1): e87540.
Sandoval NR, Kim JYH, Reeder P, Glebes TY, Aucoin HR, Warner JR, and Gill RT: A Strategy for Directing Combinatorial Genome Engineering in E. coli. PNAS 26 (2012) 10540-10545.
Sandoval NR, Mills TY, Zhang M, and Gill RT: Elucidating acetate tolerance in E. coli using a genome-wide approach. Metab Eng. 13 (2010) 214-224.
Mills TY*, Sandoval NR*, and Gill RT: Cellulosic hydrolysate toxicity and tolerance mechanisms in Escherichia coli. Biotechnol Biofuels (2009) 2:26.
Gall S, Lynch MD, Sandoval NR, and Gill RT: Parallel mapping of genotypes to phenotypes contributing to overall biological fitness. Metab Eng. 10 (2008) 382-393.
Warnecke TE, Lynch MD, Karimpour-Fard A, Sandoval NR, and Gill RT: A genomics approach to improve the analysis and design of strain selections. Metab Eng 10 (2008) 154-165.