Godbey, W T. - Tulane University - Department of Chemical and Biomolecular Engineering

个人简介

B.S., Southern Methodist University, 8/85 – 5/88, conferred May, 1988 Ph.D., Rice University, 1/97 – 8/99, conferred January, 2000 Postdoctoral, Children's Hospital/Harvard Medical School, 10/00–7/03

研究领域

Gene Delivery, Cellular Engineering, Molecular Aspects of Nonviral Transfection, Biomaterials

近期论文

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Hancock BM, McGuire KL, Tsuji S, Reil K, Hernandez V, Giacalone MJ, Godbey WT. A Single Intravesical Instillation of VAX014 Inhibits Orthotopic Superficial Bladder Tumor Implantation to Increase Survival. Anticancer Res. (2016) 36: 6243-6248. Chen X, Scapa J, Liu D, Godbey W. Cancer-specific Promoters fo rExpression-targeted Gene Therapy: ran, brms1, and mcm5. J Gene Med. (2016) 18: 89-101. Tsuji S, Chen X, Hancock B, Hernandez V, Visentin B, Sabbadini R, Giacalone M, and Godbey WT. Pre-clinical Evaluation of VAX-IP, a Novel Bacterial Minicell-Based Biopharmaceutical for Non-Muscle Invasive Bladder Cancer. Mol Ther Oncolytics (22016) 3: 16004. Duran-Lara EF, Marple J, Giesen J, Fang Y, Jordan J, Godbey WT, Marican A, Santosc LS, and Grayson SM. Investigation of Lysine-functionalized Dendrimers as Dichlorvos Detoxification Agents. Biomacromolecules (2015) 16: 3434-3444. Cortez MA, Godbey WT, Fang Y, Payne ME, Cafferty BJ, Kosakowska KA, Grayson SM. The Synthesis of Cyclic Poly(ethylene imine) and Exact Linear Analogues: An Evaluation of Gene Delivering Comparing Polymer Architectures. J Am Chem Soc. (2015) 137: 6541-6549. Chen X and Godbey WT. The Potential of the Human Osteopontin Promoter and Single-nucleotide Polymorphisms for Targeted Cancer Gene Therapy. Current Gene Therapy (2015) 15: 82-92. Fang Y, Chen X, and Godbey WT. Gene Delivery in Tissue Engineering and Regenerative Medicine. J Biomed Mater Res B Appl Biomater. (2015) 103: 1679-1699 (Epub 2014). (Note - Senior author Godbey listed as "W T G" in PubMed) Abou-Kandil A, Chamias R, Huleihel M, Godbey W, and Aboud M. Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines. PLoS ONE (2012) 7: e29934, doi:10.1371/journal.pone.0029934. Abou-Kandil A, Chamias R, Huleihel M, Godbey W, and Aboud M. Role of Caspase 9 in Activation of HTLV-1 LTR Expression by DNA Damaging Agents. Cell Cycle (2011) 10: 3337-3345. Dobek G, Zhang X, Balazs DA, and Godbey WT. Analysis of Promoters and Expression-targeted Gene Therapy, Optimization Based on Cell Behavior. FASEB J. (2011) 25: 3219-3228. Balazs DA and Godbey WT. Liposomes for Use in Gene Delivery. J Drug Deliv. (2011) 2011:326497. Dobek GL and Godbey WT. An Orthotopic Model of Murine Bladder Cancer. J Vis Exp. (2011) 48, pii:2535. doi: 10.3791/2535. http://www.jove.com/details.stp?id=2535. Zhang X, and Godbey WT. Preclinical evaluation of a gene therapy treatment for transitional cell carcinoma. Cancer Gene Therapy (2010) 1-8. Balazs DA and Godbey WT. Liposomes for Use in Gene Therapy. J Drug delivery (2010) Zhang X, Turner C, and Godbey WT. Comparison of Caspase Genes for the Induction of Apoptosis following Gene Delivery. Molecular Biotechnology (2009) 41: 236-246. Ramgopal Y, Mondal D, Venkatraman SS, Godbey WT, and Yuen GY. Controlled release of complexed DNA from polycaprolactone film: Comparison of lipoplex and polyplex release. J Biomed Mater Res B Appl Biomater. (2009) 89: 439-447. Grayson SM and Godbey WT. The role of macromolecular architecture in passively targeted polymeric carriers for drug and gene delivery. J Drug Target. (2008) 16: 329-356. Ramgopal Y, Venkatraman SS, and Godbey WT. In vitro release of complexed pDNA from biodegrdable polymer films. J Appl Polym Sci. (2008) 108: 659-664 Zhang X, Atala A, and Godbey WT. Expression-targeted Gene Therapy for the Treatment of Transitional Cell Carcinoma. Cancer Gene Ther. (2008) Mar 7; [Epub ahead of print] Godbey WT, Zhang X, and Chang F. The Importance of and a Method for Including Transfection Efficiency into Real-time PCR Data Analyses. Biotechnol Bioeng. (2008) 100: 765-772 *Spotlighted by the journal* Ramgopal Y, Mondal D, Venkatraman SS, and Godbey WT. Sustained release of complexed and naked DNA from polymer films. J Biomed Mater Res B Appl Biomater. (2008) 85B: 496-503. Zhang X and Godbey WT. Viral Vectors for Gene Delivery in Tissue Engineering. Adv Drug Del Rev (2006) 58: 515-534. Sahiner N, Godbey WT, McPherson GL, and John VT. Microgel, Nanogel and Hydrogel-hydrogel Semi-IPN Composites for Biomedical Applications: Synthesis and Characterization. Colloid Polym Sci (2006) Online version: May 2006, Pages 1 - 9, DOI 10.1007/s00396-006-1489-4, URL http://dx.doi.org/10.1007/s00396-006-1489-4. Godbey WT, Hindy S, Sherman ME, and Atala A. A Novel Use of Centrifugal Force for Cell Seeding into Porous Scaffolds. Biomaterials (2004) 25:2799-805. Godbey WT and Atala A. Directed apoptosis in Cox-2-overexpressing cancer cells through expression-targeted gene delivery. Gene Ther. 2003 Aug;10(17):1519-27.