Rolfes, Ronda J. - Georgetown College

个人简介

Ph.D. (1990) Purdue University, Biochemistry B.A. (1983) College of St. Benedict

研究领域

Regulation of gene expression; Genetics of yeasts Saccharomyces cerevisiae, Candida ablicans

近期论文

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Steidle, E.A., L.S. Chong, M. Wu, E. Crooke, D. Fiedler, A.C. Resnick, and R.J. Rolfes. "A novel inositol pyrophosphate phosphatase in Saccharomyces cerevisiae: Siw14 cleaves the ?-phosphate from 5-diphosphoinositol pentakisphosphate (5PP-IP5)." J Biological Chemistry 291 (2016): 6772-6783. Rosenwald, A.G., G. Arora, R. Ferrandino, E. Gerace, M. Mohammednetej, W. Nosair, S. Rattila, A.C. Subic and R. Rolfes. "Identification of genes in the pathogenic fungus, Candida glabrata conferring altered responses to caspofungin, a cell wall synthesis inhibitor." G3 (Genes, Genomes, Genetics) 6 (2016): 2893-2907. Ghosh, A.K., T. Wangsanut, W.A. Fonzi, and R.J. Rolfes. "The GRF10 homeobox gene regulates filamentous growth in human fungal pathogen Candida albicans." FEMS Yeast Research 15 (2015): pii: fov093. Gatti, J.W., M.C. Smithgall, S.M. Paranjape, R.J. Rolfes, and M. Paranjape. "Using electrospun poly(ethylene-oxide) nanofibers for improved retention and efficacy of bacteriolytic antibiootics.." Biomed. Microdevices 15 (2013): 887-893. Romanowski, K., A. Zaborin, V. Valuckaite, R.J. Rolfes, T. Babrowski, C. Bethel, A. Olivas, O. Zaborina, and J. C. Alverdy . "Candida albicans isolates from the gut of critically ill patients respond to phosphate limitation by expressing filaments and a lethal phenotype." PLoS ONE 7.1 (2012): e30119. Bambach, Adrienne, M.P. Fernandes, Anup Ghosh, Michael Kruppa, Deepu Alex, D. Li, William A. Fonzi, N. Chauhan, Nuo Sun, O.A. Agrellos, A.E. Vercesi, R.J. Rolfes and R. Calderone. "Goa1 of Candida albicans localizes to the mitochondria during stress and is required for mitochondrial function and virulence." Eukaryotic Cell 8 (2009): 1706-1720. Koehler, R.N., N. Rachfall, and R.J. Rolfes. "Activation of the ADE genes requires the chromatin remodeling complexes SAGA and SWI/SNF." Eukaryotic Cell 6 (2007): 1474-1485. Rolfes, R.J.. "Regulation of purine nucleotide biosynthesis: in yeast and beyond." Biochemical Society Transactions 34 (2006): 786-790. Som, I., R.N. Mitsch, J.L. Urbanowski, and R.J. Rolfes. "DNA-bound Bas1 recruits Pho2 to activate ADE genes in Saccharomyces cerevisiae." Eukaryotic Cell 4 (2005): 1725-1735. M. Shakoury-Elizeh, J. Tiedeman, J. Rashford, T. Ferea, J. Demeter, E. Garcia, R. Rolfes, P.O. Brown, D. Botstein, and C.C. Philpott. "Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae." Molecular Biology of the Cell 15 (2004): 1233-1243. L.T. Bhoite, J. Allen, E. Garcia, K. Whelihan, L.R. Thomas, I.D. Gregory, W.P. Voth, R.J. Rolfes, and D.J. Stillman. "Mutations in the Pho2 (Bas2) Transcription Factor that Differentially Affect Activation with its Partner Proteins Bas1, Pho4, and Swi5." J Biological Chemistry 277 (2002): 37612-37618. Charles Hannum, Olga I. Kulaeva, Helen Sun, Jennifer L. Urbanowski, Ashley Wendus, David J. Stillman, and Ronda J. Rolfes. "Functional Mapping of Bas2 – Identification of Activation and Bas1-Interaction Domains." J. Biological Chemistry 277 (2002): 34003-34009. Petra S. Buc and Ronda J. Rolfes. "ade9 is an allele of SER1 and plays an indirect role in purine biosynthesis." Yeast 15 (1999): 1347-1355. Fan Zhang, Martha Kirouac, Nan Zhu, Alan G. Hinnebusch and Ronda J. Rolfes. "Evidence that complex formation by Bas1p and Bas2p(Pho2p) unmasks the activation function of Bas1p in an adenine-repressible step of ADE gene transcription. ." Molecular and Cellular Biology 17 (1997): 3272-3283. Ronda J. Rolfes, Fan Zhang and Alan G. Hinnebusch. "The transcriptional activators BAS1, BAS2 and ABF1 bind positive regulatory sites as the critical elements for adenine-regulation of ADE5,7." J Biological Chemistry 272 (1997): 13343-13354. Ronda J. Rolfes and Alan G. Hinnebusch. "Translation of the yeast transcriptional activator GCN4 is stimulated by purine limitation: Implications for activation of the protein kinase GCN2." Molecular and Cellular Biology 13 (1993): 5099-5111.