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个人简介

1980-1991年就读于华西医科大学医学院,相继获医学学士、硕士和博士学位。毕业后在华医科大学附一院传染科从事感染性疾病的医疗、教学和科研工作,历任助教、讲师。1994年晋升副研究员。1996-1997年赴日本金?g大学癌症研究所分子生物学部进行合作研究。1998-2002年在美国Scripps研究所细胞生物学部做博士后研究。2002年升任研究员。

研究领域

病毒性肝炎和肝病的分子致病机理和生物治疗研究;肝富集转录因子对HBV转录复制的调控作用及机理;HBV及HCV体外复制体系的建立和应用;病毒性肝炎分子病理学;肝癌分子病理学

近期论文

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[1] Liu K, Lei XZ, Zhao LS, Tang H, Liu L. Tissue microarray for high-throughput analysisof gene expression profiles in hepatocellular carcino.W J Gastroenterols, 2005,11(9) [2] Qin S, Tang H, Zhao LS. Cloning of HBsAg-encoded genes in different vectors and their expression in Eukaryotic cells. World J Gastroenterol,2003,9(5) [3] Banks KE, Anderson AL, Tang H, .Hughes DE,et al.Hepatocyte nuclear factor 3βinhibits hepatitis B virus replication in vivo.J of Virol ,2002,76(24),12974-12980 [4] Tang H, Mclachlan A. Mechanisms of inhibition of nuclear hormone receptor-dependent hepatitis B virus replication by hepatocyte nuclear factor 3. J of Virol,2002,76(17),8572-81 [5] Tang H, Mclachlan A.Avian and mammalian hepadnaviruses have distinct transcription factor requirements for viral replication. J of Virol 2002,76(15),7462-72 [6] Tang H, Mclachlan A. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism . PNAS, 2001,98(4),1841-46 [7] Tang H, Raney AK, McLachlan A. Replication of the wild type and a natural hepatitis B virus nucleocapsid promoter variant is differentially regulated by nuclear hormone receptors in cell culture .J of Virol, 2001, 75(19),8937-48. [8] Tang H, Banks KE, Anderson AL, Mclachlan A. Hepatitis B virus transcription and replication. Drug News & Perspectives, 2001,14(6),325-334

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