马用信 - 四川大学 - 生物治疗国家重点实验室

个人简介

四川省卫生厅学术和技术带头人，华西医院医学遗传研究室 / 生物治疗国家重点实验室疾病基因组学研究室主任。中国遗传学会理事，中国遗传学会第八届人类和医学遗传委员会委员，四川省遗传学会人类与医学遗传专委会主任委员。中国细胞生物学会理事，四川省细胞生物学会副理事长。科技部国际科技合作计划项目评审专家，国家自然科学基金国际合作计划项目评审专家。《遗传》杂志编委，国际遗传学核心杂志《 PLoS Genetics 》和国际细胞和发育生物学杂志《 Stem Cells and Development 》特约审稿专家

研究领域

1.人类功能基因组学 / 疾病相关基因的克隆与功能研究： 2.疾病相关小 RNA 的鉴定与功能研究。包括与精子发生、肿瘤等疾病相关的 miRNA 等小 RNA 的分离鉴定，采用过表达和降低表达等方法研究这些小 RNA 分子的功能及其调控机制 3.RNA 结合蛋白相关研究。4.与生殖发育、疾病及肿瘤相关的表观遗传学相关研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

• Huaqin Sun, Dan Li, Shu Chen, Yanyan Liu, Xiaolin Liao, Wenqian Deng, Na Li, Mei Zeng, Dachang Tao, Yongxin Ma *. Zili inhibits transforming growth factor-beta signaling by interacting with Smad4 . J Biol Chem. 2010 ， 285(6):4243-50. Shu Chen, Mei Zeng, Huaqin Sun, Wenqian Deng, Yilu Lu, Dachang Tao, Yunqiang Liu, Sizhong Zhang & Yongxin Ma * . Zebrafish Dnd protein binds to 3'UTR of geminin mRNA and regulates its expression. BMB Rep. 2010, ;43(6):438-44. Yilu Lu, Chao Li, Kun Zhang, Huaqin Sun, Dachang Tao, Yunqiang Liu, Sizong Zhang and Yongxin Ma * 。 Identification of piRNAs in Hela cells by massive parallel sequencing. BMB Rep. 2010,(published on line). Naihong Yan ， Yilu Lu , Huaqin Sun , Dachang Tao , Wenying Liu,Sizhong Zhang , Yongxin Ma *. A microarray for microRNAs profiling in mouse testis tissues. Reproduction ， 2007 ， 133 Mei Zeng, Huaqin Sun, Shu Chen, Xinying Wang, Yuan Yang, Yunqiang Liu, Dachang Tao, Zhirong Yang, Sizhong Zhang and Yongxin Ma* . Mol Hum Reprod. 2008,14(6):331-6. Na Li, Huaqin Sun, Qiaqing Wu, Dachang Tao, Sizhong Zhang, Yongxin Ma* . Cloning and expression analysis of a novel mouse Zinc finger protein gene Znf313 abundantly expressed in testis. Journal of Biochemistry and Molecular Biology, 2007, 40 （ 2 ）： 270-276 ， Mei Zeng, Wenqian Deng, Xinying Wang, Weimin Qiu ,Yanyan Liu, Huaqin Sun, Dachang Tao, Sizhong Zhang & Yongxin Ma* . DAZL binds to the transcripts of several Tssk genes in germ cells. BMB Rep. 2008, 41(4):300-4. Naihong Yan, Yilu Lu, Huaqin Sun, Weimin Qiu, Dachang Tao, Yunqiang Liu, Huijiao Chen, Yuan Yang, Sizhong Zhang, Xiang Li, Yongxin Ma *. Microarray profiling of microRNAs expressed in the developing primates testis tissues. J Assist Reprod Genet. 2009, 26:179-186. Mei Zeng, Yilu Lu, Xiaolin Liao, Dan Li, Huaqin Sun, Suhua Liang, Sizhong Zhang, Yongxin Ma * and Zhirong Yang. DAZL binds to 3' UTR of Tex19.1 mRNAs and regulates the expression of Tex19.1. Mol Biol Rep. 2009, 36(8):2399-403. Wenqian Deng, Huaqin Sun, Yunqiang Liu, Dachang Tao, Sizhong Zhang, Yongxin Ma *. Molecular cloning and expression analysis of a zebrafish novel zinc finger protein gene rnf141. Genetics and Molecular Biology, 2009, 32(3): 594-600 L. Y. Zhang, M. Zeng, P. Chen, H. Q. Sun, D. C. Tao, Y. Q. Liu, L. Lin, Y. Yang, S. Z. Zhang, Y. X. Ma* . Identification of messenger RNA substrates for mouse T-STAR. Biochemistry (Moscow) 2009, 74 （ 11 ）： 1270-1277. Jun Zhao, Huaqin Sun, Wenqian Deng, Dan Li, Yanyan Liu, Yilu Lu, Yunqiang Liu, Dachang Tao, Sizhong Zhang and Yongxin Ma* . Piwi-like 2 Mediates Fibroblast Growth Factor Signaling during Gastrulation of Zebrafish Embryo. The Tohoku Journal of Experimental Medicine 2010, 222(1), (in press) Liao X , Deng W , Lu Y , Tao D , Liu Y , Zhang S , Ma Y * . Sp1 plays an important role in regulating the transcription of ZNF313. Cell Biol Int. 2010, 34(9): 901-5.