个人简介
入选教育部新世纪优秀人才,四川省学术和技术带头人;中国生物化学与分子生物学学会蛋白质组学专业委员授予“优秀青年学者奖”。任地方病与少数民族性疾病教育部重点实验室(贵州医科大学)学术委员会委员,中国蛋白质组组织(CNHUPO)青年学者委员会委员。
研究领域
(1) 疾病/药物蛋白质组与疾病分子机理;(2) 基因蛋白功能与肿瘤生物治疗研究;(3) 药理药靶与生物技术药物;(4) 合成生物学与微生物代谢调控。
近期论文
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1. Ziwei Liang, Yanfang Yang, Yu He, Pengbo Yang, Xixi Wang, Gu He, Peng Zhang, Hongxia Zhu, Ningzhi Xu, Xia Zhao, Shufang Liang*. SUMOylation of IQGAP1 promotes the development of colorectal cancer. Cancer Lett 2017, 411:90-99 (*通讯作者) 2. Wen Ma , Dan Zhang, Guoshun Li, Jingjing Liu, Gu He, Peng Zhang, Yamei Yu, Li Yang, Ningzhi Xu, Shufang Liang*. Antibacterial mechanism of daptomycin antibiotic against Staphylococcus aureus based on a quantitative bacterial proteome analysis. J Proteomics 2017, 150: 242-251 (*通讯作者) 3. Dan Zhang, Peng Zhang , Pengbo Yang, Yu He, Xixi Wang, Yanfang Yang, Hongxia Zhu, Ningzhi Xu,Shufang Liang*. Downregulation of ATP1A1 promotes cancer development in renal cell carcinoma. Clin Proteomics 2017, 14:15 (*通讯作者) 4. Bing Chen, Xiao Zeng, Yu He, Xixi Wang, Ziwei Liang, Jingjing Liu, Peng Zhang, Hongxia Zhu, Ningzhi Xu, Shufang Liang*. STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways. Oncotarget 2016, 7(44):71400-71416 (*通讯作者) 5. Bing Chen, Yuling Liu, Xuewen Jin, Weiliang Lu, Jingjing Liu, Qiong Yuan, Xia Zhao, Ningzhi Xu, Shufang Liang*. MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells. BMC Cancer 2014, 14:443 6. Xiao Zeng, Pengbo Yang, Bing Chen, Xuewen Jin, Yuling Liu, Xia Zhao, Shufang Liang*. Quantitative secretome analysis reveals the interactions between epithelia and tumor cells by in vitro modulating colon cancer microenvironment. J Proteomics 2013,89:51-70 (*通讯作者) 7. Hongbin Li, Guoshun Li, Xinyu Zhao, Yongkang Wu, Wen Ma, Yuling Liu, Fengming Gong, Shufang Liang*. Complementary serum proteomic analysis of autoimmune hepatitis in patients and mice. J Transl Med 2013,11:146 (*通讯作者) 8. Shufang Liang, Afu Fu, Qiang Zhang, Minghai Tang, Jin Zhou, Yuquan Wei, Lijuan Chen. Honokiol inhibits cell migration via IQGAP1 downregulation discovered by a quantitative pharmaceutical proteomic analysis. Proteomics 2010,10:1474-1483 9. Shufang Liang, Yanbao Yu, Pengyuan Yang, Sheng Gu, Yan Xue, Xian Chen. Analysis of the protein complex associated with 14-3-3 epsilon by a deuterated-leucine labeling quantitative proteomics strategy. J Chromatography B 2009, 877 (7): 627-634 10. S.F Liang, T.Y Wang, Y.C Du, H.M Bao, P.Y Yang, and X Chen. A MS-based epitope affinity tag strategy for studying protein-protein interactions occurring in hepatocellular carcinoma. Mol Cell Proteomics, 2004, 3(10): S21