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个人简介

2015年在英国圣安德鲁斯大学(University of St Andrews)获得博士学位。2015年-2017年在英国东安格利亚大学(University of East Anglia)从事博士后研究工作。2017年受聘于四川大学生物治疗国家重点实验室,任研究员。在国际期刊杂志上发表论文13篇,包括Nature 3篇(IF=40.1),其中以第一作者和共同第一作者在 Nature 共发表 2 篇 Article 形式的文章, 在Nature communications (IF=12.2), Journal of Virology, RNA, BBA Molecular and cell biology of Lipids 作为第一作者各一篇。

研究领域

1.围绕膜蛋白的结构生物学研究 2.病原微生物(耐药菌)相关的抗药性的药物靶点蛋白的结构和功能机理研究 3.基于蛋白质结构的药物靶点的开发

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Dong, H., Xiang, Q., Gu, Y., Wang, Z., Paterson, N. G., Stansfeld, P. J., He, C., Zhang, Y., Wang, W., Dong, C. (2014). Structural basis for outer membrane lipopolysaccharide insertion. Nature, 511(7507), 52–6. doi:10.1038/nature13464 2. Gu, Y*., Li, H*., Dong, H*., Zeng, Y*., Zhang, Z*., Paterson, N.G*., Stansfeld, P.J*., Wang, Z., Zhang, Y., Wang, W., Dong, C. (2016). Structural basis of outer membrane protein insertion by the BAM complex. Nature, 531(7592), 64–69. (* 共同第一) 3. Qi, X., Lan, S., Wang, W., Schelde, L. M., Dong, H., Wallat, G. D., Ly, H., Liang, Y., Dong, C. (2010). Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468(7325), 779–783. 4. Dong, H*., Zhang, Z*., Tang, X*., Paterson, N.G., Dong, C (2017) Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG. Nature communications. 2017 Aug 9;8(1):222. doi: 10.1038/s41467-017-00273-5. 5. Dong, H., Tang, X., Zhang, Z., and Dong, C (2017) Structural insight into lipopolysaccharide transport from the Gram-negative bacterial inner membrane to the outer membrane. BBA- Molecular and Cell Biology of Lipids. Biochim Biophys Acta. 2017 Aug 15. pii: S1388-1981(17)30150-6. doi: 10.1016/j.bbalip.2017.08.003. 6. Dong, H., Li, P., Böttcher, B., Elliott, R. M., & Dong, C. (2013). Crystal structure of Schmallenberg orthobunyavirus nucleoprotein − RNA complex reveals a novel RNA sequestration mechanism. RNA, 19 (8), 1129-36. doi:10.1261/rna.039057.113.5 7. Dong, H., Li, P., Elliott, R. M., & Dong, C. (2013). Structure of schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism of genome encapsidation. Journal of Virology, 87(10), 5593–601. doi:10.1128/JVI.00223-13

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