个人简介
教育经历 2001-2005 四川大学生命科学学院,学士学位 (2003-2004 美国华盛顿大学生命科学学院,交换学生) 2005-2008 四川大学生物材料工程研究中心,工学硕士 2008-2013 美国史蒂文斯理工学院化学、生化和生物医学工程系,博士 工作经历 2013-至今 四川大学生物材料工程研究中心,副研究员
研究领域
材料与细胞相互作用,及生物材料诱导干细胞定向分化的分子机制;生物医用材料(包括:3D 打印材料,纳米磷酸钙陶瓷)的制备,及其生物学评价;骨组织工程,应用生物仿生法构建组织工程化骨。
近期论文
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Xuening Chen*, Jing Wang, Jing Wang, Xiangdong Zhu, Xiao Yang, Yujiang Fan, Xingdong Zhang*.The positive role of macrophage’s secretion stimulated by BCP ceramic in the ceramic-induced osteogenic differentiation of pre-osteoblasts via Smad-related signaling pathways. RSC Advance.2016;6: 102134. Jingyu Yang, Xuening Chen*, Tun Yuan*, , Xiao Yang, Yujiang Fan, Xingdong Zhang. Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis. Materials Science & Engineering C.2017;70(Pt 2):983-91. Xuening Chen, Jing Wang, Ying Chen, Hanxu Cai, Xiao Yang, Xiangdong Zhu*, Yujiang Fan*, and Xingdong Zhang. Roles of calcium phosphate-mediated integrin expression and MAPK signaling pathways in the osteoblastic differentiation of mesenchymal stem cells. Journal of Materials Chemistry B. 2016;4:2280-9. Xuening Chen, Asli Ergun, Halil Gevgilili, Seher Ozkan, Dilhan M Kalyon*, Hongjun Wang*. Shell-core bi-layered scaffolds for engineering of vascularized osteon-like structures. Biomaterials. 2013,34(33):8203-12. Xuening Chen, Xiaoling Fu, Jian-gang Shi, Hongjun Wang*. Regulation of the osteogenesis of pre-osteoblasts by spatial arrangement of electrospun nanofibers in two- and three-dimensional environments. Nanomedicine. 2013,9(8):1283-92. XN Chen, YX Gu, JH Lee, WY Lee*, HJ Wang*. Multifunctional surfaces with biomimetic nanofibres and drug-eluting micro-patterns for infection control and bone tissue formation. Eur Cell Mater. 2012,24:237-48.