李莉 - 四川大学 - 生物材料工程研究中心

个人简介

个人经历 1997.09-2001.07，四川大学华西药学院，药学，学士 2001.09-2004.07，四川大学华西药学院，药剂学，硕士 2004.07-2005.08，成都英创科技发展有限公司，药剂研发员 2005.09-2008.06，四川大学生物材料工程研究中心，生物医学工程，博士 2008.07-2012.06，四川大学生物材料工程研究中心，助理研究员 2011-2014，四川大学生物材料工程研究中心，党支部书记，“985工程”生物医学工程与技术科技创新平台秘书 2012.07-至今，四川大学生物材料工程研究中心，副研究员，硕士生导师 2016-2017，美国宾州州立大学，生物工程系，访问学者 2009、2012和2013年获四川大学青年骨干教师奖

研究领域

1. 智能药用材料与纳米载药系统的构建； 2. 肿瘤诊疗一体化系统 3. 高分子医疗器械

近期论文

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1. Yi Lin, Yidi Yang, Jianqin Yan, Jun Chen, Jun Cao, Yuji Pu, Li Li * and Bin He. Redox/ATP switchable theranostic nanoparticles for real-time fluorescence monitoring of doxorubicin delivery. J. Mater. Chem. B, 2018, 6, 2089-2103. IF=4.543 2. T Xu, J Li, J Cao, W Gao*, Li Li*, B He. The effect of α-cyclodextrin on poly(pseudo)rotaxane nanoparticles self-assembled by protoporphyrin modified poly(ethylene glycol) for anticancer drug delivery. Carbohydrate Polymers, 2017,174:789-797 IF=4.811 3. Hao, Na; Sun, Changzhen; Wu, Zhengfei; Xu, Long; Gao, Wenxia*; Cao, Jun; Li, Li*; He, Bin. Fabrication of Polymeric Micelles with AIE and FRET for Anticancer Drug Delivery. Bioconjugate Chemistry, 2017, 28 :1944-1954, IF=4.818 4. Jiawei Sun, Lei Jiang, Yi Lin, Ethan Michael Gerhard, Xuehua Jiang, Li Li*, Jian Yang, Zhongwei Gu. Enhanced anticancer efficacy of paclitaxel through multistage tumor-targeting liposomes modified with RG D and KLA peptides. International Journal of Nanomedicine, 2017:12 1517–1537. IF=4.350 5. Lei Jiang, Li Li*, Bin He, et al, Anti-cancer efficacy of paclitaxel loaded in pH triggered liposomes, Journal of Biomedical Nanotechnology 2016; 12(1):79-90. IF=4.521 6. Lei Jiang, Li Li*, Xiao Dan He, et al. Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response. Biomaterials 2015,52: 126-139. IF=8.402 7. Xiaodan He, Li Li, Hong Su,et al. Poly(ethylene glycol)-block-poly(ε-caprolactone)– and phospholipid-based stealth nanoparticles with enhanced therapeutic efficacy on murine breast cancer by improved intracellular drug delivery. International Journal of Nanomedicine, 2015, 10: 1791-1804. IF=4.350 8. Li Li, Wen Jiang, Kui Luo, et al. Superparamagnetic Iron Oxide Nanoparticles as MRI contrast agents for Non-invasive Stem Cell Labeling and Tracking. Theranostics, 2013, 3: 595-615. IF=8.766 9. Hongmei Song, Gang Wang, Bin He, Li Li *, Caixia Li, Yusi Lai, Xianghui Xu, Zhongwei Gu*. Cationic lipid-coated PEI/DNA polyplexes with improved efficiency and reduced cytotoxicity for gene delivery into mesenchymal stem cells. International Journal of Nano, medicine, 2012, 7: 4637-4648. IF=4.350 10. Kuilin Lai, Lijie Ji, Chunyan Long, Li Li*, Bin He, Yao Wu, Zhongwei Gu*. Synthesis of functionalizable and biodegradable polymers via ring-opening polymerization of 5-benzyloxy-trimethylene carbonate and ε-caprolactone. J. Applied Polymer Science，2012, 123：2204-2210. IF=1.860 11. Yong Zhang, Ying Lei, Jing Chang, Li Li*, Bin He, ZhongweiGu*. Guidance of myoblast migration on aligned electrospun PLGA nanofibrous meshes. Materials Letters, 2012, 68: 218-221. IF=2.572 12. Kui Luo, Caixia Li, Li Li, Wenchuan She, Gang Wang*, Yao Wu, Bin He, Zhongwei Gu*. Arginine functionalized peptide dendrimers as potential gene delivery vehicles. Biomaterials, 2012, 33:4917-4927. IF=8.312 13. Li Li，Hongmei Song，Bin He, et al. Gene Transfer Efficacies of Serum-Resistant Amino Acids-Based Cationic Lipids: Dependence on Headgroup, Lipoplex Stability and Cellular Uptake. Interantional Journal of Pharmceutics, 2011, 408: 183-190. IF=3.649