郭立坤 - 四川大学 - 生物材料工程研究中心

个人简介

2000年7月毕业于辽宁大学材料工程专业，2000年9月考入中国科学院成都有机化学研究所高分子化学与物理研究室攻读硕士学位。2003年7月获得理学硕士学位。同年9月考入四川大学生物材料工程研究中心攻读博士学位，2005年3月至2008年4月作为联合培养博士研究生赴日本国家材料研究所（NIMS）进行实验研究，2008年6月获生物医学工程博士学位。主要科研工作经历 2005.3－2008.3 日本国家材料研究所助理研究员 2008.7－2010.6 四川大学，生物材料中心，讲师 2010.7－四川大学生物材料中心，副研究员 2012.2－四川大学生物材料中心，硕士生导师

研究领域

1. 干细胞的定向诱导分化 2. 材料与细胞的相互作用关系3. 生物材料的表面修饰

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Likun Guo, Naoki Kawazoe, Yujiang Fan, Yoshihiro Ito, Junzo Tanaka, Tetsuya Tateishi, Xingdong Zhang, Guoping Chen; Chondrogenic Differentiation of Human Mesenchymal Stem Cells on Photoreactive Polymer-Modified Surfaces; Biomaterials 29 (2008) 23-32. 2. Likun Guo, Naoki Kawazoe, Tetsuya Tateishi, Xingdong Zhang, Guoping Chen; Osteogenic Differentiation of Human Mesenchymal Stem Cells on Chargeable Polymer-Modified Surfaces; Journal of Biomedical Materials Research Part A 2008, vol. 87, pp. 903-912 . 3. Likun Guo, Yujiang Fan, Naoki Kawazoe, Guoping Chen, Junzo Tanaka, Tetsuya Tateishi and Xingdong Zhang; Effect of Surface Electrostatic Property on Chondrogenic Differentiation of Human Mesenchymal Stem Cells; Key Engineering materials vols.330-332(2007) pp1189-1192. 4. Hongxu Lu1, Likun Guo1, Michal J. Wozniak, Naoki Kawazoe, Tetsuya Tateishi, Xingdong Zhang, Guoping Chen. Effect of cell density on adipogenic differentiation of mesenchymal stem cells. Biochemical and Biophysical Research Communications. 381(2009), 322-327. 5. Naoki Kawazoe, Likun Guo, Michal J. Wozniak, Yumie Imaizumi, Tetsuya Tateishi, Xingdong Zhang, and Guoping Chen Adipogenic Differentiation of Mesenchymal Stem Cells on Micropatterned Polyelectrolyte Surfaces J. Nanosci. Nanotechnol. 9(2009), 230–239. 6. Hongxu Lu, Likun Guo, Naoki Kawazoe, Tetsuya Tateishi，Guoping Chen. Effects of Poly(L-lysine), Poly(acrylic acid) and Poly(ethylene glycol) on the Adhesion, Proliferation and Chondrogenic Differentiation of Human Mesenchymal Stem Cells. Journal of Biomaterials Science 20 (2009) 577-589. 7. Yuan T, Li K, Guo L, Fan H, Zhang X. Modulation of immunological properties of allogeneic mesenchymal stem cells by collagen scaffolds in cartilage tissue engineering. Journal of Biomedical Materials Research Part A 2011 Sep 1;98(3):332-41. 8. Liu, Y; Guo, LK; Huang, L; Deng, XM Preparation and properties of a biodegradable polymer as a novel drug delivery system. Journal of Applied Polymer Science 90: 3150-3156, 2003. 9. Xianmo Deng, Likun Guo, Yu Liu, Jianyuan Hao The degradation of biodegradable polymer in different pH values and accelerated degradation by increasing temperature or performing in 6%H2O2-PBS solution J Polym Mater 20（2003）285-91. 10. Li Zhang, Tun Yuan, Likun Guo, Xingdong Zhang An in vitro Study of Collagen Hydrogel to Induce the Chondrogenic Differentiation of Mesenchymal Stem Cells. Journal of Biomedical Materials Research 2012 ;100A(10):2717-25.