王刚 - 四川大学 - 生物材料工程研究中心

个人简介

2006.6，四川大学生命科学学院，博士(分子遗传学及基因工程)； 2009.6，四川大学，国家生物医学材料工程技术研究中心(NERCB)，博士后(生物医学工程)； 2009.7-2015.7，NERCB，副研究员； 2015.5-2015.7，西班牙纳瓦拉大学合作研究员； 2015.7-至今，NERCB，研究员； 2016.11-2017.12，美国耶鲁大学医学院分子生物物理与生物化学系，访问学者

研究领域

1. 建立高效的非病毒材料介导的骨骼肌原位基因传递和表达体系； 2. 应用骨骼肌原位基因传递/表达体系进行肿瘤靶向联合生物治疗； 3. 生物材料的作用机理及应用研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Linyu Pu, Jiali Wang, Na Li, Qiuxia Chai, Juan M. Irache, Gang Wang*, James Zhenggui Tang, Zhongwei Gu*. Synthesis of Electroneutralized Amphiphilic Copolymers with Peptide Dendrons for Intramuscular Gene Delivery. ACS Applied Materials & Interfaces. 2016, 8 (22):13724–13734. (IF: 7.504) 2. Jianlin Chen, Jing Luo, Ying Zhao, Linyu Pu, Xuejing Lu, Rong Gao, Gang Wang*, Zhongwei Gu*. Increase in Transgene Expression by Pluronic L64-Mediated Endosomal/Lysosomal Escape through Its Membrane-Disturbing Action. ACS Applied Materials & Interfaces. 2015, 7 (13): 7282-7293. (IF: 7.145) 3. Jing Luo, Caixia Li, Jianlin Chen, Rong Gao*, Gang Wang*, Zhongwei Gu. An efficient method for in vitro gene delivery via regulation of cellular endocytosis pathway. International Journal of Nanomedicine. 2015; 10:1667-1678. (IF: 4.32) 4. Linyu Pu, Yanyan Geng, Sijia Liu, Jianlin Chen, Kui Luo, Gang Wang*, Zhongwei Gu*. Electroneutralized Amphiphilic Triblock Copolymer with a Peptide Dendron for Efficient Muscular Gene Delivery. ACS Applied Materials & Interfaces. 2014; 6 (17):15344-15351. (IF: 6.723) 5. Hongmei Song, Sijia Liu, Caixia Li, Yanyan Geng, Gang Wang*, Zhongwei Gu*. Pluronic L64-mediated stable HIF-1α expression in muscle for therapeutic angiogenesis in mouse ischemic limb. International Journal of Nanomedicine. 2014; 9:3439-3452. (IF: 4.383) 6. Jun Cao, Ting Su, Longgui Zhang, Rong Liu, Gang Wang*, Bin He, Zhongwei Gu. Polymeric Micelles with Citraconic Amide as pH-Sensitive Bond in Backbone for Anticancer Drug Delivery. International Journal of Pharmaceutics. 2014; 471:28-36. (IF: 3.65) 7. Sijia Liu, Liping Ma, Rui Tan, Qiong Lu, Yanyan Geng, Gang Wang*, Zhongwei Gu*. Safe and efficient local gene delivery into skeletal muscle via a combination of Pluronic L64 and modified electrotransfer. Gene Therapy. 2014; 21:558-565. (IF: 4.196) 8. Kui Luo, Caixia Li, Li Li, Wenchuan She, Gang Wang*, Zhongwei Gu*. Arginine functionalized peptide dendrimers as potential gene delivery vehicles. Biomaterials. 2012; 33:4917-4927. (IF: 7.604) 9. Gang Wang, Caixia Li, Kui Luo, Hongmei Song, Zhongwei Gu. The 5th generation of poly(l-lysine) dendrimer is a potential carrier for in vivo in gene delivery. Drug Discovery Today. 2010; 15:1191. (IF: 6.422) 10.Gang Wang, Ying Cui, Guangfeng Zhang, Alan Garen, Xu Song. Regulation of proto-oncogene transcription, cell proliferation, and tumorigenesis in mice by PSF protein and a VL30 noncoding RNA. Proc. Natl. Acad. Sci. USA. 2009; 106:16794-16798. (IF: 9.432)