金洪 - 四川大学 - 生命科学学院

个人简介

理学博士，博士后，中国植物保护学会鼠害防治专业委员会委员。先后主持国家重点研发计划项目子课题2项，已发表SCI论文30多篇，其中以第一作者或通讯作者在European Journal of Medicinal Chemistry、Journal of Agricultural and Food Chemistry、Pest Management Science等国际权威SCI杂志上发表10多篇。担任Journal of Agricultural and Food Chemistry、European Journal of Medicinal Chemistry、ACS Sustainable Chemistry & Engineering等SCI杂志审稿人。

研究领域

1、绿色农药的化学与生物学研究以我国农业病虫害为作用靶标，微生物/植物代谢产物或商业化学农药为先导，创制具有自主知识产权的新型绿色农药；开展微生物/植物代谢产物的分离与纯化，发现新型先导化合物；开展化学农药的合成方法研究 2、退化草地的生物防治综合配套技术研究针对草地退化严重、草畜失衡、生产力低效问题，以现有退化草地的生物防治技术为基础，开展鼠虫害监测技术研究；针对不同退化程度草地，开展以生态防治为重点的鼠虫害综合防治技术的研究和示范

近期论文

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Yongtian Zhao, Qi Wang, Xia Wu, Mingfang Jiang, Hong Jin*, Ke Tao*, Taiping Hou, Unraveling the polypharmacology of a natural antifungal product, eugenol, against Rhizoctonia solani, Pest Management Science, 2021, doi: 10.1002/ps.6400. Yongtian Zhao, Na Yang, Yiming Deng, Ke Tao, Hong Jin*, Taiping Hou, Mechanism of action of novel pyrazole carboxamide containing a diarylamine scaffold against Rhizoctonia solani, Journal of Agricultural and Food Chemistry, 2020, 68, (40), 11068-11076. Jian Yang, Yongtian Zhao, Jun Wan, Mingfang Jiang, Hong Jin*, Ke Tao, Taiping Hou, Synthesis and biological evaluation of novel benodanil-heterocyclic carboxamide hybrids as a potential succinate dehydrogenase inhibitors, Molecules, 2020, 25, 4291. Aigui Zhang, Ying Yue, Jian Yang, Jiaxing Shi, Ke Tao, Hong Jin*, Taiping Hou, Design, synthesis, and antifungal activities of novel aromatic carboxamides containing a diphenylamine scaffold, Journal of Agricultural and Food Chemistry, 2019, 67, (17), 5008-5016. Yuanhang Ren, Jiaxing Shi, Yangping Mu, Ke Tao, Hong Jin*, Taiping Hou, AW1 neuronal cell cytotoxicity: The mode of action of insecticidal fatty acids，Journal of Agricultural and Food Chemistry, 2019, 67, 43, 12129-12136. Aigui Zhang, Ying Yue, Yihua Yang, Jian Yang, Ke Tao, Hong Jin*, Taiping Hou*, Discovery of N-(4-fluoro-2-(phenylamino)phenyl)-pyrazole-4-carboxamide as potential succinate dehydrogenase inhibitors, Pesticide Biochemistry and Physiology, 2019, 158, 175-184. Aigui Zhang, Yihua Yang, Ying Yue, Ke Tao, Taiping Hou*, Hong Jin*, N-[2-[(3-Chlorophenyl)amino]-phenyl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide: Synthesis, crystal structure, molecular docking and biological activities, Chemistry & Biodiversity, 2019, 16, e1900118. Yuanhang Ren, Liqin He, Hong Jin*, Ke Tao*, Taiping Hou, Cytotoxicity evaluation and apoptosis-inducing effects of furanone analogues in insect cell line SL2, Food and Agricultural Immunology, 2018, 29, 964-975. Aigui Zhang, Jingya Zhou, Ke Tao, Taiping Hou, Hong Jin*, Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors, Bioorganic & Medicinal Chemistry Letters, 2018, 28, 3042-3045. Xiao-Xiao Zhang, Hong Jin*, Yuan-Jie Deng, Xu-Heng Gao, Yong Li, Yong-Tian Zhao, Ke Tao, Tai-Ping Hou*, Synthesis and biological evaluation of novel pyrazole carboxamide with diarylamine-modified scaffold as potent antifungal agents, Chinese Chemical Letters, 2017, 28, 1731-1736. Hongyu Wang, Xuheng Gao, Xiaoxiao Zhang, Hong Jin*, Ke Tao, Taiping Hou*， Design, synthesis and antifungal activity of novel fenfuram-diarylamine hybrids，Bioorganic & Medicinal Chemistry Letters, 2017, 27(1), 90-93. Hong Jin*, Jingya Zhou, Tao Pu, Aigui Zhang, Xuheng Gao, Ke Tao, Taiping Hou, Synthesis of novel fenfuram-diarylether hybrids as potent succinate dehydrogenase inhibitors, Bioorganic Chemistry, 2017, 73, 76-82. Fang Wen, Hong Jin*, Ke Tao*, Taiping Hou, Design, synthesis and antifungal activity of novel furancarboxamide derivatives, European Journal of Medicinal Chemistry, 2016, 120(2), 244-251. Mingjing Chen, Hong Jin*, Ke Tao, Taiping Hou, Synthesis and bioactivity evaluation of novel benzamide derivatives containing a diphenyl ether moiety, Journal of Pesticide Science, 2014, 39(4): 187-192. Hong Jin, Haoyu Zhao, Feihu Zhao, Shihong Li, Wei Liu, Guoping Zhou, Ke Tao, Taiping Hou*, Efficient epoxidation of chalcones with urea-hydrogen peroxide under ultrasound irradiation, Ultrasonics Sonochemistry, 2009, 16(3), 304-307. Hong Jin, Yucong Geng, Zhiyi Yu, Ke Tao, Taiping Hou*, Lead optimization and anti-plant pathogenic fungi activities of daphneolone analogues from Stellera chamaejasme L., Pesticide Biochemistry and Physiology, 2009, 93(3), 133-137. Hong Jin, Liyu Xiang, Fang Wen, Ke Tao, Qian Liu, Taiping Hou*, Improved synthesis of chalconoid-like compounds under ultrasound irradiation, Ultrasonics Sonochemistry, 2008, 15(5): 681-683. 金洪, 陈鸶, 侯若彤, 王玉良, 陈淑华, 杨志荣. 溴代二羟基二苯醚类化合物的合成与抑菌活性研究, 有机化学, 2006(10), 1424-1428.