个人简介
1993年毕业于四川大学生物工程系获学士学位 1996年毕业于四川大学生物工程系获硕士学位 1999年毕业于中国协和医科大学获博士学位 1999年起在美国耶鲁大学分子生物物理与生物化学系作博士后研究 2002年起任美国耶鲁大学分子生物物理与生物化学系Associate Research Scientist,Research Assistant Professor 2006年起任四川大学生命科学学院教授、博导,四川省分子生物学及生物技术重点实验室主任
研究领域
筛选及鉴定肿瘤、干细胞相关的长非编码RNA,并研究其作用机制。发现长非编码RNA的新作用机制。
近期论文
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1、Lan Y, Xiao X, He Z, Luo Y, Wu C, Li L, Song X*. Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer. Nucleic Acids Research,46(11): 5809–21, 2018 2、Chen H, Du G, Song X*, Li L. Non-coding transcripts from enhancers: new insights into enhancer activity and gene expression regulation. Genomics, Proteomics & Bioinformatics, 15, 201-207, 2017 3、Li L, Feng T, Lian Y, Zhang G, Garen A, Song X*. Role of human noncoding RNAs in the control of tumorigenesis. Proc. Natl. Acad. Sci. U S A.,106 (31):12956-61,2009 3、Wang G, Cui Y, Zhang G, Garen A, Song X*. Regulation of proto-oncogene transcription, cell proliferation, and tumorigenesis in mice by PSF protein and a VL30 noncoding RNA. Proc. Natl. Acad. Sci. U S A., 106 (39) 16794-98, 2009 4、Garen A, Song X. Regulatory roles of tumor-suppressor proteins and noncoding RNA in cancer and normal cell functions. Int J Cancer. 122(8):1687-9,2008 5、Song X, Sun Y, Garen A. From the cover: Roles of PSF protein and VL30 RNA in reversible gene regulation. Proc. Natl. Acad. Sci. U S A.,102(34): 12189-93. 2005(封面论文) 6、Song X, Sui A, Garen A. Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis. Proc. Nat.l Acad. Sci. U S A. 101(2): 621-6, 2004 7、Song X, Wang B, Bromberg M, Hu Z, Konigsberg W, Garen A. Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model. Proc. Natl. Acad. Sci. USA. 99: 6269-6273. 2002 8、Song X, Bao M, Li D, Li Y. Advanced glycation in D-galactose induced mouse aging model. Mech Ageing Dev, 108:241-253, 1999