个人简介
1978.9-1982.7 在华西医科大学 药学专业 理科学士学位, 1983.6~1984.6 中国协和医科大学&中国医学科学院学习。 2004.9~2007年.10中国药科大学 微生物与生化药学专业 博士学位 2007.3-2007.8 国家留学及基金委公派高级研究学者赴美留学。 1982.7~1998.6 中国协和医科大学&中国医学科学院输血研究所任实习研究员、助理研究员、副研究员、研究员。 1999年4月至今,四川大学华西药学院任教,博士生及硕士生导师,
研究领域
1. 基因工程药物的研究 2. 天然生化药物(包括微生物药物)的研究 3. 蛋白质工程药物的设计
近期论文
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1.Gao Ling,Zhang Chun,Li Lingling,Liang Lan,Deng Xuan,Wu Wutong,Su Zhiguo, Yu Rong*, Construction, Expression and Refolding of a Bifunctional Fusion Protein Consisting of C-Terminal 12-Residue of Hirudin-PA and Reteplase,Protein Journal, 2012,31(4):328~336 2. Pi-Ping Lv, Yu-Feng Ma, Rong Yu, Hua Yue, De-Zhi Ni, Wei Wei,* and Guang-Hui Ma Targeted Delivery of Insoluble Cargo (Paclitaxel) by PEGylate Chitosan Nanoparticles Grafted with Arg-Gly-Asp (RGD) Molecular Pharmaceutics 2012 , 9 (6) :1736-1747 3.Xiang Silong,Ma Yuyuan* ,Yan Qipo,Lv Maomin,Zhao Xiong,Yin Huiqiong, Zhang Nian,Jia Junting, Yu Rong*,Zhang, Jingang, Construction and characterization of an infectious replication competent clone of porcine endogenous retrovirus from Chinese miniature pigs, Virology Journal,2013,10 :228 4.Zhang Chun,Liu Yongdong(*),Zhao Dawei,Li Xiunan, Yu Rong* ,Su Zhiguo, Facile purification of Escherichia coli expressed tag-free recombinant human tumor necrosis factor alpha from supernatant,Protein Expression and Purification, 2014,95:195~203 5.Cai Yingting,Bao Jingxiao,Lao Xingzhen(*) ,Zheng Heng,Chen Jianhua, Yu Rong*, Computational design, functional analysis and antigenic epitope estimation of a novel hybrid of 12 peptides of hirudin and reteplase,Journal of Molecular Modeling, 2015, 21(9) ;299 6.Li Yaqiong,Li Xiunan (*),Chen Chao,Zhao Dawei,Su Zhiguo,Ma Guanghui, Yu Rong* , A rapid, non-invasive and non-destructive method for studying swelling behavior and microstructure variations of hydrogels,Carbohyd rate Polymers,2016.10.20,151:1251~1260 7.Shuang Yin,Chun Zhang Zenglan Li Qi Wang HongShi,RongYu * YongdongLiu,Zhiguo Su I dentification, characterization, and stabilization of the deamidation degradation of recombinant human tumor necrosis factor-α Process Biochemistry , 2016 , 53,3216-223 8.Zhang Chun, Yu Rong * ZenglanLi, CuiFeng, Qi Wang,Yongdong Liu, Zhiguo Su Development of long-acting ciliary neurotrophic factor by site-specific conjugation with different-sized polyethylene glycols and transferrin International Journal of Pharmaceutics 2017, 529(1–2), 275-284 9.Yaqiong Li,Xiunan Li * ,Chao Chen,Dawei Zhao,Zhiguo Su,Guanghui, Ma, Rong Yu* , Sol–gel transition characterization of thermosensitive hydrogels based on water mobility variation provided by low field NMR,Journal of Polymer Research, 2017. 4, 24(25): 25 10.Liu Liping. Zhang Chun (co-first), Liu Yongding, Yu Rong *, Zhiguo Su et al. Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of the (6-maleimidocaproyl)-hydrazone derivative of doxorubicin. Molecular Pharmaceutics. 2017. (Manuscript ID: mp-2017-00497t). (accepted)