黄文 - 四川大学 - 华西药学院

个人简介

1999–2002，四川大学，博士 2002–2004，北京大学，博士后 2004–2006，北京中医药大学，药学院 2006–2009，四川大学，生物治疗国家重点实验室 2009–至今，四川大学，华西医院中药药理实验室主任

研究领域

天然药物和传统药物药理学，天然药物及中药新药临床前研究与评价

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. pH-Responsive nanoparticles based on ibuprofen prodrug as drug carriers for inhibition of primary tumor growth and metastasis. J Mat Chem B 2017, 5(33): 6860-6868.(IF 4.543，通讯作者) 2. Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release. Free Radic Biol Med 2017, 108: 247-257. (IF 5.6059，通讯作者) 3. Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway. Scientific reports 2017, 7: 12. (IF 4.2589，通讯作者) 4. Synthesis, characterization, and biological studies of diosgenyl analogs. Journal of Asian Natural Products Research 2017, 19(3): 272-298. (通讯作者) 5. Preventive effect of a novel diosgenin derivative on arterial and venous thrombosis in vivo. Bioorganic & Medicinal Chemistry Letters 2016, 26(14): 3364-3369. (通讯作者) 6. One compound of saponins from Disocorea zingiberensis protected against experimental acute pancreatitis by preventing mitochondria-mediated necrosis. Scientific reports 2016, 6: 35965. (IF 4.2589，通讯作者) 7. Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release. Scientific reports 2016, 6: 36222. (通讯作者) 8. Synthesis, characterization, and biological studies of diosgenyl analogs. J Asian Nat Prod Res 2016: 1-27. (通讯作者) 9. 9,10-Dihydrophenanthrene derivatives and one 1,4-anthraquinone firstly isolated from Dioscorea zingiberensis C. H. Wright and their biological activities. Fitoterapia 2016, 109: 20-24. (通讯作者) 10. Novel polyacetylenes from Coreopsis tinctoria Nutt. Journal of Asian Natural Products Research 2015, 17(7): 744-749. (通讯作者) 11. Reference Intervals for Hemoglobin and Age- and Gender-Related Trends in the Population of Southwest China. Clinical Laboratory 2015, 61(12): 1831-1836. (通讯作者) 12. Haloemodin as Novel Antibacterial Agent Inhibiting DNA Gyrase and Bacterial Topoisomerase I. Journal of Medicinal Chemistry 2014, 57(9): 3707-3714. (IF 6.2589，通讯作者) 13. Micro-flowers changing to nano-bundle aggregates by translocation of the sugar moiety in Janus TA nucleosides. Chemical Communications 2013, 49(36): 3742-3744. (IF6.3189，通讯作者) 14. Anti-thrombosis effect of diosgenyl saponins in vitro and in vivo. Steroids 2013, 78(11): 1064-1070. (通讯作者) 15. Synthesis of Diosgenin-Ibuprofen Derivatives and Their Activities against Insulin-Dependent Diabetes Mellitus. Chemical & Pharmaceutical Bulletin 2013, 61(5): 532-538. (通讯作者) 16. Determination of deltonin in rat plasma by using HPLC-MS/MS and the application of this method in pharmacokinetic studies. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2013, 931: 1-5. (通讯作者) 17. Cytotoxicity and apoptosis-inducing effect of steroidal saponins from Dioscorea zingiberensis Wright against cancer cells. Steroids 2012, 77(12): 1219-1227. (通讯作者) 18. Ultrasonic and fermented pretreatment technology for diosgenin production from Diosorea zingiberensis CH Wright. Chemical Engineering Research & Design 2011, 89(2A): 239-247. (通讯作者)