个人简介
Education
BS Biology, BA Chemistry, 2001, The University of New Orleans
PhD Biochemistry, 2006, The University of Texas at Austin
NIH Kirschstein Postdoctoral Fellow, 2007-2010, The Scripps Research Institute
研究领域
Chemical Biology and Biochemistry
Pharmaceutical Chemistry
Natural product genome mining and comparative genomics
Natural product drug discovery and chemical ecology
Natural product biosynthesis
Development of natural product detection systems
Development of novel strategies for manipulation of natural product biosynthetic pathways
近期论文
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Guo, J.†;Melançon, C. E., III†; Lee, H. S.; Groff, D.; Schultz, P. G. Evolution of Amber Suppressor tRNAs for Efficient Bacterial Production of Proteins Containing Nonnatural Amino Acids. Ang. Chem. Int. Ed. 2009, 48, 9148-9151.
Thibodeaux, C. J.; Melançon, C. E., III; Liu, H.-w. Natural Product Sugar Biosynthesis and Enzymatic Glycodiversification. Ang. Chem. Int. Ed. 2008, 51, 9814-9859.
Zhang, H.; White, J. A.; Melançon, C. E., III; Kwon, H.-j.; Yu, W.-l.; Liu, H.-w. Elucidation of the Kijanimicin Gene Cluster: Insights into the Biosynthesis of Spirotetronate Antibiotics and Nitrosugars. J. Am. Chem. Soc. 2007, 129, 14670-14683.
Thibodeaux, C. J.; Melançon, C. E., III; Liu, H.-w. Unusual Sugar Biosynthesis and Natural Product Glycodiversification. Nature 2007, 446, 1008-1016.
Melançon, C. E., III; Liu, H.-w. Engineered Biosynthesis of Macrolide Derivatives Bearing the Non- Natural Deoxysugars 4-epi-D-Mycaminose and 3-N-Monomethylamino-3-Deoxy-D-Fucose. J. Am. Chem. Soc. 2007, 129, 4896-4897.