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个人简介

徐章润,教授,博士生导师。1994年毕业于东北大学化学系,2005年师从方肇伦院士获博士学位,2009-2010年美国加州大学伯克利分校访问学者。2006年被评为辽宁省普通高等学校优秀青年骨干教师,2009年入选教育部新世纪优秀人才支持计划,2011年入选辽宁省百千万人才工程百人层次,2017年入选沈阳市高层次人才领军人才。主要研究方向包括微流控分析、光谱分析和生物分析等。先后主持国家自然科学基金仪器专项项目和国家自然科学基金面上项目6项。在国内外重要学术期刊发表论文80余篇,参编著作1部,授权国家发明专利6项,曾获辽宁省自然科学一等奖和教育部自然科学一等奖。

研究领域

微流控分析、光谱分析、生物分析

近期论文

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1.Wen-Qi Ye, Yun-Yun Wei, Dan-Ni Wang, Chun-Guang Yang, Zhang-Run Xu*. A digital microfluidic platform based on a near-infrared light-responsive shape-memory micropillar array. Lab on a Chip, 2021, DOI: 10.1039/D0LC01324B 2.Danni Wang, Wanyi Xue, Xiuyan Ren, Zhangrun Xu*. A review on sensing mechanisms and strategies for telomerase activity detection. Trends in Analytical Chemistry, 2021, 134, 116115. 3.Yingzhi Zhang‡, Qiwen Su‡, Dan Song, Jiayuan Fan, Zhangrun Xu*. Label-free detection of exosomes based on ssDNA-modulated oxidase-mimicking activity of CuCo2O4 nanorods. Analytica Chimica Acta, 2021, 1145: 9-16. 4.Yun-Yun Wei, Ying-Zhi Zhang, Dan Song, Jin Li, Zhang-Run Xu*. Alkaline phosphatase-regulated in situ formation of Prussian blue nanoparticles for multicolor visual sensing of biomarkers. Talanta, 2021, 228: 122222. 5.Yingzhi Zhang, Junye Jiao, Yunyun Wei, Danni Wang, Chunguang Yang*, Zhangrun Xu*. A Plasmonic Colorimetric Biosensor for Sensitive Exosome Detection via Enzyme-Induced Etching of Gold Nanobipyramid@MnO2 Nanosheet Nanostructures. Analytical Chemistry, 2020, 92(22): 15244–15252. 6.Ying Liu, Shuai Yue, Ya-Ning Wang, Yue Wang, Zhang-Run Xu*. A multicolor-SERS dual-mode pH sensor based on smart nano-in-micro particles. Sensors and Actuators B: Chemical, 2020, 310: 127889. 7.Wen-Shu Zhang, Ya-Ning Wang, Zhang-Run Xu*. High sensitivity and non-background SERS detection of endogenous hydrogen sulfide in living cells using core-shell nanoparticles. Analytica Chimica Acta, 2020, 1094: 106-112 8.Danni Wang, Xiayu Zhao, Yunyun Wei, Wanyi Xue, Zhangrun Xu*. A pH-responsive colorimetric detection of human telomerase RNA based on a three-dimensional DNA amplifier. Analytica Chimica Acta, 2020, 1111: 67-74. 9.Jin Li, Yun-Yun Wei, Zhang-Run Xu*.Visual detection of acid phosphatase based on hollow mesoporous manganese dioxide nanospheres. Analytica Chimica Acta, 2020, 1138: 1-8. 10.Rui Guo, Dan-Ni Wang, Yun-Yun Wei, Ying-Zhi Zhang, Chun-Guang Yang*, Zhang-Run Xu*. Colloidal photonic crystal array chip based on nanoparticle self-assembly on patterned hydrophobic surface for signal-enhanced fluorescent assay of adenosine. Microchimica Acta, 2020, 187: 194. 11.Xiang-Nan He, Ya-Ning Wang, Zhang-Run Xu*. Accurate quantitative detection of cell surface sialic acids with a background-free SERS probe. Talanta, 2020, 209: 120579. 12.Yue Wang, Jing Liu, Yukihiro Ozaki*, Zhangrun Xu*, Bing Zhao*. Effect of TiO2 on Altering Direction of Interfacial Charge Transfer in a TiO2-Ag-MPY-FePc System by SERS. Angewandte Chemie International Edition, 2019, 131(24): 8256-8260. 13.Yue Wang, Jing Liu, Xueqi Zhao, Chunguang Yang, Yukihiro Ozaki, Zhangrun Xu*, Bing Zhao*, and Zhi Yu*. A chiral signal amplified sensor for enantioselective discrimination of amino acids based on charge transfer-induced SERS. Chemical Communications, 2019, 55(65): 9697-9700. 14.Yingzhi Zhang, Danni Wang, Shuai Yue, Yanbing Lu, Chunguang Yang, Jin Fang, Zhangrun Xu*. Sensitive multicolor visual detection of exosomes via dual signal amplification strategy of enzyme-catalyzed metallization of Au nanorods and hybridization chain reaction, ACS Sensors, 2019, 4(12): 3210-3218. 15.Yunyun Wei, Danni Wang, Yingzhi Zhang, Jinhong Sui, Zhangrun Xu*. Multicolor and photothermal dual-readout biosensor for visual detection of prostate specific antigen. Biosensors and Bioelectronics, 2019, 140, 111345. 16.Wen-Shu Zhang, Ya-Ning Wang, Yue Wang, Zhang-Run Xu*. Highly reproducible and fast detection of 6-thioguanine in human serum using a droplet-based microfluidic SERS system. Sensors and Actuators B: Chemical, 2019, 283: 532-537. 17.Danni Wang, Yingzhi Zhang, Xiayu Zhao, Zhangrun Xu*. Plasmonic colorimetric biosensor for visual detection of telomerase activity based on horseradish peroxidase-encapsulated liposomes and etching of Au nanobipyramids. Sensors and Actuators B: Chemical, 2019, 296: 126646. 18.Xiao-Ting Sun, Rui Guo, Dan-Ni Wang, Yun-Yun Wei, Chun-Guang Yang, Zhang-Run Xu*. Microfluidic preparation of polymer-lipid Janus microparticles with staged drug release property. Journal of Colloid and Interface Science, 2019, 553: 631-638. 19.Danni Wang, Rui Guo, Yunyun Wei, Yingzhi Zhang, Xiayu Zhao, Zhangrun Xu*. Sensitive multicolor visual detection of telomerase activity based on catalytic hairpin assembly and etching of Au nanorods. Biosensors and Bioelectronics, 2018, 122: 247-253. 20.Shuai Yue, Xiao-Ting Sun, Yue Wang, Wen-Shu Zhang, Zhang-Run Xu*. Microparticles with Size/Charge Selectivity and pH Response for SERS Monitoring of 6-thioguanine in Blood Serum. Sensors and Actuators B: Chemical, 2018, 273: 1539-1547. 21.Ya-Ning Wang, Ying Zhang, Wen-Shu Zhang, Zhang-Run Xu*. A SERS substrate of mesoporous g-C3N4 embedded with in situ grown gold nanoparticles for sensitive detection of 6-thioguanine. Sensors and Actuators B: Chemical, 2018, 260: 400-407. 22.Rui Guo, Xiao-Ting Sun, Ying Zhang, Dan-Ni Wang, Chun-Guang Yang*, Zhang-Run Xu*. Three-dimensional poly(lactic-co-glycolic acid) /silica colloidal crystal microparticles for sustained drug release and visualized monitoring. Journal of Colloid and Interface Science, 2018, 530: 465-472. 23.Yun-Yun Wei, Xiao-Ting Sun, Zhang-Run Xu*. One-step synthesis of bifunctional PEGDA/TiO2 composite film by photopolymerization for the removal of Congo red. Applied Surface Science, 2018, 445: 437-444. 24.Xiao-Ting Sun, Ying Zhang, Dong-Hua Zheng, Shuai Yue, Chun-Guang Yang, Zhang-Run Xu*. Multitarget sensing of glucose and cholesterol based on Janus hydrogel microparticles. Biosensors and Bioelectronics, 2017, 92: 81-86. 25.Shuai Yue, Xiaoting Sun, Ning Wang, Yaning Wang, Yue Wang, Zhangrun Xu*, Mingli Chen, and Jianhua Wang. SERS-Fluorescence Dual-Mode pH-Sensing Method Based on Janus Microparticles. ACS Applied Materials & Interfaces, 2017, 9, 39699-39707. 26.Ying Zhang, Ya-Ning Wang, Xiao-Ting Sun, Lei Chen, Zhang-Run Xu*. Boron nitride nanosheet/CuS nanocomposites as mimetic peroxidase for sensitive colorimetric detection of cholesterol. Sensors and Actuators B: Chemical, 2017, 246: 118-126. 27.Mei Liu, Xiao-Ting Sun, Chun-Guang Yang, Zhang-Run Xu*. On-chip preparation of calcium alginate particles based on droplet templates formed by using a centrifugal microfluidic technique. Journal of Colloid and Interface Science, 2016, 466: 20-27. 28.Xiao-Ting Sun, Mei Liu, Zhang-Run Xu*. Microfluidic fabrication of multifunctional particles and their analytical applications, Talanta, 2014, 121, 163-177. 29.Chun-Guang Yang, Zhang-Run Xu*, Abraham P. Lee*, Jian-Hua Wang. A microfluidic concentration-gradient droplet array generator for the production of multi-color nanoparticles, Lab on a Chip, 2013, 13(14), 2815-2820. 30.Chun-Guang Yang, Ying-Fan Wu, Zhang-Run Xu*, Jian-Hua Wang*. A radial microfluidic concentration gradient generator with high-density channels for cell apoptosis assay, Lab on a Chip, 2011, 11: 3305-3312.

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