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个人简介

1984年河北大学学士,1992年中科院兰州化物所博士,2000年瑞士洛桑联邦理工学院(EPFL)博士后;河北大学助教(1984)、讲师(1992)、副教授(1994)、教授(2001)。2003年至今东北大学教授。

研究领域

微纳流控分析,纸基分析装置,生化分析,电泳,色谱

近期论文

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1.Han Gao, Jia-Juan Liu, Xiu-Yu Fang and Zhi-Yong Wu. Detection of urine protein by a paper-based analytical device enhanced with ion concentration polarization effect. Microfluid Nanofluid 2019, 23: DOI:10.1007/s10404-019-2220-3 2.Lei Liu, Mao-Rong Xie, Yu-Zhu Chen and Zhi-Yong Wu. Simultaneous electrokinetic stacking and sepration of anionic and cationic species on a paper fluidic channel. Lob Chip 2019, 19, 845-850 3.Ting Zhou, Jia-Juan Liu, Ye Xu* and Zhi-Yong Wu*. Fast and sensitive screening detection of tetracyclines with a paper-based analytical device. Microchemical Journal 2019, 145, 703-707 4.Xiu-Xiu Zhang, Jia-Juan Liu, Yu Cai, Shuang Zhao* and Zhi-Yong Wu. A field amplification enhanced paper-based analytical device with a robust chemiluminescence detection module. Analyst 2019, 144, 498-503 5.王华杰,刘元敏,李光宇,吴志勇* 单个纳米孔电流脉冲法探究鱼精蛋白与单链DNA的相互作用. 分析化学(Chinese J Anal Chem),2018, 46(6):851-857. 6.孙珊珊,刘元敏,李光宇,吴志勇* 离子液体电解质对DNA穿过α-溶血素纳米孔的影响,分析化学(Chinese J Anal Chem),2018, 46(6):858-864. IP 0.709 7.Fang Fang, Yan-Qin He, Li Tian, Yun-Yun Li, Zhi-Yong Wu*. Making of a single solid-state nanopore on the wall of fused silica capillary. Roy Soc Open Sci.2018,5: 171633. http://dx.doi.org/10.1098/rsos.171633 8.Han Gao, Mao‑Rong Xie, Jia‑Juan Liu, Fang Fang, Zhi‑Yong Wu*. Electrokinetic stacking on paper‑based analytical device by ion concentration polarization with ion exchange membrane interface. Microfluid Nanofluid. 2018 22:50 https://doi.org/10.1007/s10404-018-2071-3 9.Song-Fang Xie, Han Gao, Li-Li Niu, Zhen-Sheng Xie, Fang Fang, Zhi-Yong Wu* Fu-Quan Yang*. Carrier ampholyte-free isoelectric focusing on a paper-based analytical device for the fractionation of proteins.J Sep Sci . 2018, 41: 2085–2091. IP 2.741 10.Xiu-Xiu Zhang, Yi-Zhen Song, Fang Fang, Zhi-Yong Wu*. Sensitive paper-based analytical device for fast colorimetric detection of nitrite with smartphone.Anal Bioanal Chem2018 410:2665-2669. IP 3.331 11.Lei Liu, Mao-Rong Xie, Fang Fang, Zhi-YongWu*. Sensitive colorimetric detection of Cu2+ by simultaneous reaction and electrokinetic stacking on a paper-based analytical device. Microcheml J. 2018, 139: 357-362 12.Yi-Zhen Song, Xiu-Xiu Zhang, Jia-Juan Liu, Fang Fang, Zhi-Yong Wu*. Electrokinetic stacking of electrically neutral analytes with paper-based analytical device. Talanta 2018 182: 247-252. IP 4.035 13.Ji-Cheng Niu, Ting Zhou, Li-Li Niu, Zhen-Sheng Xie, Fang Fang, Fu-Quan Yang*, Zhi-Yong Wu*. Simultaneous pre-concentration and separation on simple paper-based analytical device for protein analysis. Anal Bioanal Chem 2018 410:1689-1695 14.Yi-Chen Song, Xiu-Xiu Zhang, Biao Ma, Zhi-Yong Wu*, Zi-Qiang Zhang* Performance of electrokinetic stacking enhanced paper –based analytical device wit smartphone for fast detection of fluorescent whitening agent. Anal Chim Acta, 2017, 995: 85-90. IP 4.725 15.Biao Ma, Song-Fang Xie, Lei Liu, Fang Fang, Zhi-Yong Wu*. Two orders of magnitude electrokinetic stacking of proteins on a simple paper fluidic channel. Anal Meth, 2017, 9:2703-2709 16.Zhi-Yong Wu*, Biao Ma, Song-Fang Xie, Kun Liu, Fang Fang, Simultaneous electrokinetic concentration and separation of proteins on a paper-based analytical device. RSC Adv., 2017, 7:4011-4016 17.Biao Ma, Yi-Zhen Song, Ji-Cheng Niu, Zhi-Yong Wu*. Highly efficient sample stacking by enhanced field amplification on a simple paper device. Lab Chip, 2016, 16:3460-3465 18.Fang Fang, Zhang Na, Liu Kun, and Wu Zhi-Yong*. Hydrodynamic and electrodynamic flow mixing in a novel total glass chip mixer with streamline herringbone pattern, Microfluid Nanofluid.2015, 18(5): 887-895 19.Zhang Da–Wei, Zhang Hui-Qin, Tian Li, Wang Lin, Fang Fang, Liu Kun and Wu Zhi-Yong*. Microfabrication-free fused silica nanofluidic interface for on chip electrokinetic stacking of DNA. Microfluid Nanofluid. 2013, 14(1-2): 69-76 20.Wu Zhi-Yong*, Fang Fang, He Yan-Qin, Li Ting-Ting, Li Jing-Jing, and Li Tian. Flexible and Efficient Eletrokinetic Stacking of DNA and Proteins at an HF Etched Porous Junction on a Fused Silica Capillary. Anal Chem2012, 84 (16 ): 7085-7091 21.Wu Zhi-Yong*, Li Cui-Ye, Guo Xiao-Li, Li Bo, Zhang Da-Wei, Xu Ye and Fang Fang. Nanofracture on fused silica microchannel for Donnan exclusion based electrokinetic stacking of biomolecules. Lab Chip2012, 12(18): 3408-3412 22.Min Kyoung-Ik, Lee Tae-Ho, Park Chan Pil, Wu Zhi-Yong, Girault Hubert H, Ryu Ilhyong, Fukuyama Takahide, Mukai Yu, Kim Dong-Pyo*. Monolithic and flexible polyimide film microreactors for organic microchemical applications fabricated by laser ablation, Angew Chemie (Int ed in Eng) 2010, 49(39): 7063-7 23.Qu Bai-Yan, Wu Zhi-Yong*, Fang Fang, Bai Zhi-Ming, Yang Dong-Zhi, Xu Shu-Kun. A glass microfluidic chip for continuous blood cell sorting by a magnetic gradient without labeling, Anal Bioanal Chem2008, 392(7): 1317-1324 24.Wu Zhi-Yong*, Chen Kun, Qu Bai-Yan, Tian Xiao-Xi, Wang Xiao-Jie and Fang Fang. A thermostat chip of indium tin oxide glass substrate for static polymerase chain reaction and in situ real time fluorescence monitoring, Anal Chim Acta2008, 610(1): 89-96 25.吴志勇*, 方芳. 电场耦合法芯片电泳柱上电导检测特性研究, 高等学校化学学报2008, 29(2): 283-287 26.Wang Ya-Rong, Li Jing-Jing, Wu Zhi-Yong*, Fan Jun-Gang and Fang Fang. Improvement of Porous Electro-conductive Membrane Preparation and Its Application in Sample Injection Pre-concentration in the Capillary Electrophoresis of Proteins, Chinese J Anal Chem(分析化学)2008, 36(7): 879-884 27.张娜, 方芳, 吴志勇*. 集成电极的复合混沌混合芯片的快速制备及表征, 功能材料与器件学报2008, 14(6): 943-948 28.Qu Bai-Yan, Wu Zhi-Yong*, Tian Xiao-Xi, Chen Kun and Fang Fang. Optimization of direct whole blood PCR amplification with applications on a static thermostat chip.(Author abstract)(Report), Anal Bioanal Chem 2007, 389(5): 1499-1504 29.Wu Zhi-Yong*, Fang Fang, Josserand Jacques and Girault Hubert H. On-column conductivity detection in capillary-chip electrophoresis, Electrophoresis2007, 28(24): 4612-4619 30.吴志勇*, 田晓溪, 渠柏艳, 陈坤, 方芳. 透明导电玻璃(ITO)基材自加热传感静态芯片聚合酶链反应(PCR),高等学校化学学报2007, 28(12): 2259-2263 31.Zhang Tao, Fang Qun, Wang Shi-Li, Qin Li-Feng Wang Ping, Wu Zhi-Yong, Fang Zhao–Lun*. Enhancement of signal-to-noise level by synchronized dual wavelength modulation for light emitting diode fluorimetry in a liquid-core-waveguide microfluidic capillary electrophoresis system. Talanta 2005, 68(1): 19-24 32.Bai Xiao-Xia, Wu Zhi-Yong, Josserand J, Jensen H, Schafer H and Girault, H H*. Passive conductivity detection for capillary electrophoresis, Anal Chem2004, 76(11): 3126-3131 33.Wu Zhi-Yong, Jensen Henrik, Gamby Jean, Bai Xiao-Xia and Girault Hubert H*. A flexible sample introduction method for polymer microfluidic chips using a push/pull pressure pump, Lab Chip2004, 4(5): 512-515 34.Lion Niels, Rohner Tatiana C, Dayon Loïc, Arnaud Isabelle L, Damoc Eugen, Youhnovski Nikolay, Wu Zhi-Yong, Roussel Christophe, Josserand Jacques, Jensen Henrik, Rossier Joël S, Przybylski Michael and Girault Hubert H*. Microfluidic systems in proteomics, Electrophoresis 2003, 24(21): 3533-3562 35.Wu Zhi-Yong, Xanthopoulos Nicolas, Reymond Frédéric, Rossier Joël S and Girault Hubert H*. Polymer microchips bonded by O2-plasma activation, Electrophoresis 2002, 23(5): 782-90

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