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个人简介

教育背景: 2002.9 - 2007.6, 博士, 化学, California Institute of Technology, Pasadena, CA, USA 1999.9 - 2002.6, 硕士,物理化学,复旦大学化学系 1996.2 - 1999.9, 学士,化学,复旦大学化学系 工作经历: 2019.3至今, 浙江大学ZJUI学院副教授,新加坡南洋理工大学化学与生物化学系客座教授 2010.8 – 2019.2, 新加坡南洋理工大学化学与生物化学系南洋助理教授 2007.8 – 2010.7, 美国哈佛医学院/麻省总医院博士后

研究领域

化学生物学 生物无机化学 核酸纳米科学

近期论文

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Wang L., Zhu Z., Li B.*, Shao F.*, “One-Dimensional Assemblies of a DNA Tetrahedron: Manipulations on the Structural Conformation and Single-Molecule Behaviors” ACS Appl. Bio Mater. 2019 2 (3), 1278–1285. Zhang H., Ba S., Mahajan D., Lee J. Y., Ye R., Shao F., Lu L., Li T., "Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems" Nano Lett. 2018,18(11):7383-7388. (IF: 12.080) Zhu X., Wu J., Shao F.,* Hu X., “A Reversible Thermal Cycling of DNA Material for Efficient Cellulose Hydrolysis"ACS Appl. Bio Mater. 2018, 1(4), 1118-1123. He L. Sun X., Zhang H., Shao F.* "G‐quadruplex Nanowires Direct the Efficiency and Selectivity of Electrocatalytic CO2 Reduction" Angew. Chem. Int. Ed. 2018, 57, 12453 –12457. (IF:12.102) Meng Z, Kubar T, Mu Y, Shao F* "A MD-QM Theoretical Study of DNA-Mediated Charge Transport in Hydrated Ionic Liquids" J Chem. Theory. Comput. 2018, 14 (5), 2733–2742. (IF: 5.399) Wu Q, Amrutkar S, Shao F* "Sulfinate based selective labelling of 5-hydroxy methylcytosine: Application to biotin pull down assay" Bioconj. Chem. 2018 29(2), 245-249. (IF: 4.818) He L, Meng ZY, Xu D, Shao F* "Dual Functional Dinuclear Platinum Complex with Selective Reactivity towards c-myc G-quadruplex" Sci Rep 2018 767, doi:10.1038/s41598-017-19095-y Wang LY, Meng ZY, Martina F, Shao H, Shao F* "Fabrication of Circular Assemblies with DNA Tetrahedrons: From Static Structures to a Dynamic Rotary Motor" Nucleic Acid Res. 2017, 45(21), 12090-12099. (IF:11.561) Wu JY, Meng, ZY, Lu YP, Shao F* “Efficient Long-Range Charge Transport through G-quadruplex” Chem Eur J. 2017 23(56) 13980-13985. (IF: 5.317) Peng Y, Huang Y, Zhu Y, Chen B, Wang L, Lai Z, Zhang Z, Zhao M, Tan C, Yang N, Shao F, Han Y, Zhang H, “Ultrathin Two-Dimensional Covalent Organic Framework Nanosheets: Preparation and Application in Highly Sensitive and Selective DNA Detection” J. Am. Chem. Soc. 2017, 139, 8698 - 8704. (IF:13.858) Wong JR, Shao F* "Hole Transport in A-form DNA/RNA Hybrid Duplexes" Sci Rep, 2017, 7, 40293. (IF: 4.259) He L, Meng Z, Chen X, Li T, Shao F* "Aza-bridged bisphenanthrolinyl Pt(II) complexes: efficient stabilization and topological selectivity on telomeric G-quadruplexes" J. Inorg. Biochem 2017, 166, 135-140. (IF:3.348) Xuan S, Meng Z, Wu X, Wong J, Devi G, Yeow E, Shao F*, "Efficient DNA-Mediated Electron Transport in Ionic Liquids" ACS Sus Chem & Eng 2016 4 6703 - 6711. (IF: 5.951) He L, Chen X, Meng Z, Wang J, Tian K, Li T, Shao F*, "Octahedral ruthenium complexes selectively stabilize G-quadruplexes" Chem. Comm. 2016, 52, 8095 - 8098. (IF:6.319) Devi G, He L, Xu B, Li T, Shao F*, "In-stem thiazole orange reveals the same triplex intermediate for pH and thermal unfolding of i-motifs" Chem. Comm. 2016, 52, 7261 - 7264. (IF:6.319) Wu Q, Wong JR, Yeo LQ P, Zhang D, Shao F*, "Methylation on CpG repeats modulates hydroxymethylcytosine induced duplex destabilization" RSC Adv. 2016, 6, 48858 - 48862. (IF:3.108) Li T, Zhang H, Hu L, Shao F*, "Topoisomerase-Based Preparation and AFM Imaging of Multi-Interlocked Circular DNA" Bioconj. Chem, 2016 27, 616 - 620. (IF: 4.818) Wong JR, Lee K, Shu J, Shao F*, "Magnetic Fields Facilitate DNA-Mediated Charge Transport" Biochemistry, 2015 54(21), 3392-3399. (IF: 2.938). Shu J, Wang Q, Yong K, Shao F, Lee K "Programmable DNA-Mediated Multitasking Processor" J Phys Chem B 2015 119(17), 5639-5644. (IF: 3.177). Xu, B, Devi, G, Shao F* “Regulation of Telomeric i-motif Stability by 5-methylcytosine and 5-hydroxymethylcytosine Modification” Org. Biomol. Chem. 2015, 13, 5646 - 5651. (IF: 3.564)

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