个人简介
学习简历: 2008.9-2011.7 东亚大学生命资源科学学院(韩国),博士 2003.9-2006.6 华中农业大学农业微生物国家重点实验室,硕士 1999.9-2003.6 华中农业大学生命科学技术学院,学士 工作简历: 2013.12-至今 武汉大学药学院,讲师 2011.11-2013.11 武汉大学基础医学博士后流动站,博后 2006.11-2008.5 广东中大南海海洋生物技术国家工程中心
研究领域
微生物来源活性天然产物的生物合成研究:利用比较基因组学、宏基因组学等研究手段发掘新的天然产物生物合成基因簇;基于分子水平解答天然产物生物合成中一些关键问题,进而改进并优化相关代谢路径以实现产物的高产或修饰。
近期论文
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1.Tao, W., Zhu, M., Deng, Z., and Sun Y. (2013) Biosynthesis of Tetronate Antibiotics: A Growing Family of Natural Products with Broad Biological Activities. Sci China Chem. 56:1364–1371 2.Kanchanabanca, C*., Tao, W*., Hong, H., Liu, Y., Hahn, F., Samborskyy, M., Deng, Z., Sun, Y., and Leadlay, P. F. (2013) Unusual acetylation-elimination in the formation of tetronate antibiotics. Angew Chem Int Edit. 52:5785-8 (*co-first author) 3.Tao, W., Lee, M. H., Wu, J., Kim, N. H., Kim, J. C., Chung, E. S., Hwang, E. C., and Lee, S. W. (2012) Inactivation of chloramphenicol and florfenicol by a novel chloramphenicol hydrolase.Appl Environ Microbiol. 78:6295-6301 4.Tao, W., Lee, M. H., Yoon, M. Y., Kim, J. C., Malhotra, S., Wu, J., Hwang, E. C., and Lee, S. W. (2011) Characterization of two metagenome-derived esterases that reactivate chloramphenicol by counteracting chloramphenicol acetyltransferase. J Microbiol Biotechnol. 21:1203–1210 5.Tao, W., Lee, M. H., Wu, J., Kim, N. H., and Lee, S. W. (2011) Isolation and characterization of a family VII esterase derived from alluvial soil metagenomic library. J Microbiol. 49:178-185 6.Lee, M. H., Hong, K. S., Malhotra, S., Park, J. H., Hwang, E. C., Choi, H. K., Kim, Y. S., Tao, W., and Lee, S. W. (2010) A new esterase EstD2 isolated from plant rhizosphere soil metagenome.Appl Microbiol Biotechnol. 88:1125-1134 7.Li, W*., Wu, J*., Tao, W., Zhao, C., Wang, Y., He, X., Chandra, G., Zhou, X., Deng, Z., Chater, K. F., and Tao, M. (2007) A genetic and bioinformatic analysis of Streptomyces coelicolorgenes containing TTA codons, possible targets for regulation by a developmentally significant tRNA. FEMS Microbiol Lett. 266:20-28