沈坤 - 武汉大学

个人简介

学习简历： 2008.9 – 2013.7 中国科学院上海有机化学研究所，理学博士 2004.9 – 2008.6 武汉大学化学与分子科学学院，理学学士工作简历： 2018.9至今武汉大学药学院，副研究员 2013.8 – 2018.7 美国杜克大学化学系，博士后

研究领域

1. 合成方法学，手性药物与天然产物的不对称合成 2. 创新药物的研究与开发 3. 药物分子作用机制研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Shen, K.; Wang, Q.* “Copper-Catalyzed Alkene Aminoazidation as a Rapid Entry to 1,2-Diamines and Installation of an Azide Reporter onto Azahetereocycles.” J. Am. Chem. Soc. 2017, 139, 13110–13116. 2. Shen, K.;# Logan, A. W. J.;# Colell, J. F. P.;# Bae, J.; Ortiz, G. X.; Theis, T.; Warren, W. S.;* Malcolmson, S. J.;* Wang, Q.* “Diazirines as Potential Universal Molecular MRI Tags: Probing the Requirements for Efficient and Long-Lived SABRE-Induced Hyperpolarization.” Angew. Chem. Int. Ed. 2017, 56, 12112–12116. (Selected as Very Important Paper and Highlighted on Front Cover.) 3. Shen, K.; Wang, Q.* “Copper-Catalyzed Aminoalkynylation of Alkenes with Hypervalent Iodine Reagents.” Chem. Sci. 2017, 8, 8265–8270. 4. Hemric, B. N.; Shen, K.; Wang, Q.* “Copper-Catalyzed Amino Lactonization and Amino Oxygenation of Alkenes Using O-Benzoylhydroxylamines.” J. Am. Chem. Soc. 2016, 138, 5813–5816.(Highlighted in Synfacts.) 5. Shen, K.; Wang, Q.* “Copper-catalyzed Aminotrifluoromethylation of Alkenes: A Facile Synthesis of CF3-Containing Lactams.” Org. Chem. Front. 2016, 3, 222–226. 6. Shen, K.; Wang, Q.* “Copper-Catalyzed Diamination of Unactivated Alkenes with Hydroxylamines.”Chem. Sci. 2015, 6, 4279–4283. 7. Shen, K.; Han, X.;* Lu, X.* Hu, Z. “Cationic Pd(II)-Catalyzed Arylative Cyclization of 1,6-Enynes with Arylboronic Acids.” Tetrahedron Lett. 2017, 58, 3768–3771. 8. Shen, K.; Han, X.;* Xia, G.; Lu, X.* “Cationic Pd(II)-Catalyzed Cyclization of N-tosyl-aniline Tethered Alkynyl Ketones Initiated by Hydropalladation of Alkynes: A Facile Way to 1,2-Dihydro- or 1,2,3,4-Tetrahydroquinoline Derivatives.” Org. Chem. Front. 2015, 2, 145–149. (HOT articles in Organic Chemistry Frontiers in 2015 and Celebrateing the 80th Birthday of Professor Ei-ichi Negishi.) 9. Shen, K.; Han, X.;* Lu, X.* “Cationic Palladium(II)-Catalyzed Reductive Cyclization of Alkyne-Tethered Ketones or Aldehydes Using Ethanol as Hydrogen Source.” Org. Lett. 2013, 15, 1732–1735. 10. Shen, K.; Han, X.;* Lu, X.* “Cationic Palladium(II)-Catalyzed Highly Enantioselective Arylative Cyclization of Alkyne-Tethered Enals or Enones Initiated by Carbopalladation of Alkynes with Arylboronic Acids.” Org. Lett. 2012, 14, 1756–1759.