刘鹏 - 武汉大学

个人简介

2010-至今武汉大学药学院 2009-2010 香港大学研究助理 2004-2008 香港大学博士 2003-2004 香港大学研究助理 2000-2003 兰州大学硕士 1996-2000 兰州大学学士

研究领域

1. 抗病毒，抗肿瘤药物及前体药物的设计、合成与开发。2. 具有生物活性的杂环化合物的合成方法研究

近期论文

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1. Dingshan Zhou, Wei Tuo, Hao Hu, Jianrong Xu, Hongzhuan Chen, Zhigang Rao, Yuling Xiao, Xianming Hu, Peng Liu*. Synthesis and activity evaluation of tilorone analogs as potential anticancer agents.European Journal of Medicinal Chemistry, 2013, 64, 432-441. 2. Yungen Liu, Xiangguo Guan, Ella Lai-Ming Wong, Peng Liu, Jie-Sheng Huang, and Chi-Ming Che. Nonheme Iron-Mediated Amination of C(sp3)−H Bonds. Quinquepyridine-Supported Iron-Imide/Nitrene Intermediates by Experimental Studies and DFT Calculations. J. Am. Chem. Soc., 2013, 135, 7194. 3. Peng Liu, Yuxi Li, Haiyu Wang, Zhiming Wang, Xianming Hu. Synthesis of substituted quinolines by iron catalyzed oxidative coupling reactions. Tetrahedron Letters, 2012, 53, 6654-6656. 4. Hao Hu, Zhigang Rao, Jianrong Xu, Qingfu Zhu, Hans-Josef Altenbach, Hongzhuan Chen, Dingshan Zhou, Yuling Xiao, Xianbing Ke, Hao Guo, Zhongyuan Wu, Peng Liu*, Xianming Hu. 16-Morpholino quaternary ammonium steroidal derivatives as neuromuscular blocking agents: synthesis, biological evaluation and in silico probe of ligand-receptor interaction. European Journal of Medicinal Chemistry, 2012, 332-347. 5. Peng Liu, Zhiming Wang, Jue Lin, Xianming Hu. An Efficient Route to Quinolines and Other Compounds by Iron Catalyzed Cross-Dehydrogenative Coupling Reactions on Glycine Derivatives. European Journal of Organic Chemistry 2012, 1583-1589. 6. Peng Liu, Zhiming Wang, Xianming Hu. Highly Efficient Synthesis of Ureas and Carbamates from Amides by Iodosylbenzene Induced Hofmann Rearrangement. European Journal of Organic Chemistry 2012, 1994-2000. 7. Peng Liu, Yungen Liu, Ella Lai-Ming Wong, Song Xiang, Chi-Ming Che. Iron Oligopyridine Complexes as Efficient Catalysts for Practical Oxidation of Arenes, Alkanes, Tertiary Amines and N-Acyl Cyclic Amines with Oxone. Chemical Science 2011, 2, 2187-2195. 8. Hao Guo, Guolan Zhang, Tao Zhang, Xianran He, Zhongyuan Wu, Yuling Xiao, Yuanhu Pan, Guofu Qiu,Peng Liu, Xianming Hu. Synthesis, characterization and biological evaluation of some 16β-azolyl-3β-amino-5α-androstane derivatives as potential anticancer agents. European Journal of Medicinal Chemistry 2011, 9, 3662-3674. 9. Peng Liu, Cong-Ying Zhou, Song Xiang, Chi-Ming Che. Highly Efficient Oxidative Carbon-Carbon Coupling with SBA-15-Supported Iron Terpyridine Catalyst. Chemical Communications 2010, 46, 2739-2741. 10. Peng Liu, Ella Lai-Ming Wong, Angella Wing-Hoi Yuen, Chi-Ming Che. Highly Efficient Alkene Epoxidation and Aziridination Catalyzed by Iron(II) Salt +4,4′,4′′-Trichloro-2,2′:6′,2′′-terpyridine/4,4′′-Dichloro-4′-O-PEG-OCH3-2,2′:6′,2′′-terpyridine. Organic Letters 2008, 10, 3275-3278. 11. Wing-Kei Chan, Peng Liu, Man-Kin Wong, Chi-Ming Che. Highly Diastereoselective Epoxidation of Allyl-Substituted Cycloalkenes Catalyzed by Metalloporphyrins. Organic Letters 2004, 6, 1597-1599.