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1. Xu G , Kong L, Xu L, Gao Y, Jiang M, Cai Y-S, Hong K, Hu Y, Liu P, Deng Z, Price NP, Chen W*. (2018) Coordinated biosynthesis of the purine nucleoside antibiotics aristeromycin and coformycin in Actinomycetes. Appl Environ Microbiol. 84(22). DOI: 10.1128/AEM.01860-18 (*通讯作者) 2. Liu Y, Gong R, Liu X, Zhang P, Zhang Q, Cai Y-S, Deng Z, Winkler M, Wu J*, Chen W*. (2018) Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090. Microb Cell Fact. 17:131. (*共通讯作者) 3. Gong R, Qi J, Wu P, Cai Y-S, Ma H, Liu Y, Duan H, Wang M, Deng Z, Price N, Chen W*. (2018) An ATP-dependent ligase with substrate flexibility involved in assembly of the peptidyl nucleoside antibiotic polyoxin. Appl Environ Microbiol. 84(13). (*通讯作者) 4. Gao Y#, Xu G#, Wu P#, Liu J, Deng Z, Chen W*. (2017) Biosynthesis of 2’-chloropentostatin and 2’-amino-2’-deoxyadenosine highlights a single gene cluster responsible for two individual pathways in Actinomadura sp. ATCC 39365. Appl Environ Microbiol. 83(10). (*通讯作者) 5. Wu P#, Wan D #, Xu G #, Wang G, Ma H, Wang T, Gao Y, Qi J, Chen X, Zhu J, Li Y-Q, Deng Z, Chen W*. (2017) An unusual protector-protégé strategy for the biosynthesis of purine nucleoside antibiotics. Cell Chem Biol. 24(2):171-181 (*通讯作者) 6.He N#, Wu P#, Lei Y, Xu B, Zhu X, Xu G, Gao Y, Qi J, Deng Z, Tang G, Chen W*, Xiao Y*. (2017) Construction of the octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzyme and a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics.Chem Sci. 8:444-451. (*共通讯作者) 7. Zhao H, Wang L, Wan D, Qi J, Gong R, Deng Z, Chen W*. (2016) Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570. Microb Cell Fact. 15:160. (*通讯作者) 8. Qi J, Wan D, Ma H, Liu Y, Gong R, Qu X, Sun Y, Deng Z, Chen W*. (2016) Deciphering carbamoylpolyoxamic acid biosynthesis reveals unusual acetylation cycle associated with tandem reduction and sequential hydroxylation. Cell Chem Biol. 23(8):935-944. (*通讯作者) (Featured as Issue Highlights in Cell Chem Biol) 9. Chen W#, Li Y#, Li J, Wu L, Li Y, Wang R, Deng Z, Zhou J. (2016) An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis. Protein Cell. 7(9):673-683. (#共第一作者) 10.Chen W, Qi J, Wu P, Wan D, Liu J, Deng Z. (2016) Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes. J Ind Microbiol Biotechnol. 43(2-3):401-17. 11.Qi J, Liu J, Wan D, Wang Y, Cai Y, Feng X, Wu P, Li S, Qiu G, Yang S, Chen W*, Deng Z. (2015) Metabolic engineering of an industrial polyoxin producer for the targeted overproduction of designer nucleoside antibiotics. Biotechnol Bioeng. 112(9):1865-1871. (*通讯作者) (Featured as Spotlight in Biotechol Bioeng) 12. Chen W, Dai D, Wang C, Huang T, Zhai L, Deng Z. (2013) Genetic dissection of the polyoxin building block-carbamoylpolyoxamic acid biosynthesis revealing the "pathway redundancy" in metabolic networks. Microb Cell Fact. 12:121. (Most accessed paper, Top 2) 13. Xu D, Liu G, Cheng L, Lu X, Chen W*, Deng Z*. (2013) Identification of Mur34 as the novel negative regulator responsible for the biosynthesis of muraymycin in Streptomyces sp. NRRL 30471. PLoS One. 8(10):e76068 (*共通讯作者) 14. Zhai L, Lin S, Qu D, Hong X, Bai L, Chen W*, Deng Z*. (2012) Engineering of an industrial polyoxin producer for the rational production of hybrid peptidyl nucleoside antibiotics. Metab Eng. 14(4):388-93. (*共通讯作者) 15. Doroghazi J, Ju K, Brown D, Labeda D, Deng Z, Metcalf W, Chen W*, Price N*. (2011) Genome sequences of three tunicamycin-producing Streptomyces strains; S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396. J Bacteriol. 193(24):7021-2. (*共通讯作者) 16. Cheng L, Chen W*, Zhai L, Xu D, Huang T, Lin S, Zhou X, Deng Z*. (2011) Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471. Mol Biosyst. 7(3):920-927. (*共通讯作者) 17. Chen W#, Qu D#, Zhai L, Tao M, Wang Y, Lin S, Price NP, Deng Z. (2010) Characterization of the tunicamycin gene cluster unveiling unique steps involved in its biosynthesis. Protein Cell. 1(12):1093-1105. (#共第一作者) 18. Chen W, Huang T, He X, Meng Q, You D, Bai L, Li J, Wu M, Li R, Xie Z, Zhou H, Zhou X, Tan H, Deng Z. (2009) Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H. J Biol Chem. 284(16): 10627-10638.
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