周本宏 - 武汉大学

个人简介

1984年9月—1988年6月，湖北中医药大学药学专业，获学士学位1988年武汉大学人民医院（湖北省人民医院）药学部 1998年获武汉大学医学院（原湖北医科大学）医学硕士学位 2007年获武汉大学有机化学专业理学博士学位 2000年武汉大学人民医院临床药学研究室副主任 1999年11月晋升为副教授 2004年12月晋升为主任药师 2008年11月晋升为教授、2013年晋升为三级岗位 2001年至今先后兼任武汉大学药学院药剂学系副主任，临床药物研究所副所长,人民医院药学部副主任

研究领域

1. 中药及天然药物活性成分的研究: 2. 临床药理学及药物代谢的研究； 3. 药物新制剂的研究。 4. 临床药学

近期论文

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1. Ben-hong Zhou, Xiao-jun Li, Xian-ming Hu, et al. Antidepressant-like activity of the Gastrodia elata ethanol extract in mice. Fitoterapia .77（2006）： 592-594 （SCI） 2. Ben-hong Zhou, Zhen-hua Wu, Xiao-jun Li,et al. Analysis of ellagic acid in Pomegranate rinds by capillary electrophoresis and high performance liquid chromatography. Phytochemical Analysis .2008，19：86-89 （SCI） 3. Benhong Zhou, Xiaojun Li, Zhenpeng Qiu and Gang Liu. Effect of leaves of Apocynum venetum L. on the activity of MAO in mice. Journal of Medicinal Plants Research. 2011,5(12).2584-2586 (SCI) 4. Benhong Zhou ，Zhenpeng Qiu, Gang Liu1, Chun Liu, and Jie Zhang. Spermicidal and antigonococcal effects of tannins from pomegranate rind .Journal of Medicinal Plants Research 2012， Vol.6（7）,1334-1339, (SCI) 5. Fu-Chao,Bao-Xia Fang,Peng Li,Jin-Guo Yang,and Ben-Hong Zhou﹡ Compatibility of butorphanol and droperidol in 0.9% sodium chloride injection Am J Health-Syst Pharm. Vol 70 Mar 15, 2013, 515-519, (SCI corresponding author, ) 6. Zhenpeng Qiu a,1, Benhong Zhou b,1, Long Jin b, Honglian Yu a, Lijuan Liu a, Youyi Liu a, Chengchen Qin a,Shuixiang Xie c, Fan Zhu a,⇑ In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells. Food and Chemical Toxicology. 59 (2013) 428–437 (SCI, co-author) 7. Benhong Zhou，Jie Tu，Jing Zhou, Huilan Yi, Yue Wu， Gang Liu Purification of Pomegranate Pericarps (Punica granatum L.) Extracts with Macroporous Resins and Evaluation of Antioxidant Activities in Vivo Advanced Materials Research Vols. 998-999 (2014) pp 296-301（EI） 8. Benhong Zhou, Huilan Yi, Jun Tan, Yue Wu, Gang Liu Zhengpeng Qiu＊ Anti-Proliferative Effects of Polyphenols from Pomegranate Rind ( Punica granatum L.) on EJ Bladder Cancer Cells Via Regulation of p53/miR-34a Axis, Phytothearpy Research, 29: 415– 422 (2015),(SCI) 9. Fu-Chao Chen, MD, Xiao-Ya Shi, MD, Peng Li, PhD, Jin-Guo Yang, PhD, and Ben-Hong Zhou＊, PhD Stability of Butorphanol–Tropisetron Mixtures in 0.9% Sodium Chloride Injection for Patient-Controlled Analgesia Use Medicine Volume 94, Number 6, February 2015 （SCI, corresponding author） 10. Fu-Chao Chen, Hui Xiong, Jinguo Yang, Baoxia Fang, Benhong Zhou＊ Butorphanol and Ketamine Combined in Infusion Solutions for Patient-Controlled Analgesia Administration: A Long-Term Stability Study Med Sci Monit, 2015; 21: 1138-1145 （SCI, corresponding author） 11. XIN GUO1，ZHENG-HUA CHEN1，HUI -LING WANG1，ZHONG-CHUN LIU1，XIAO-PING WANG1，BEN-HONG ZHOU2，CAN YANG1，XUE -PING ZHANG1，LING XIAO1，CHANG SHU1，JIAN-XIN CHEN1，and GAO -HUA WANG1. WSKY, a traditional Chinese decoction, rescues cognitive impairment associated with NMDA receptor antagonism by enhancing BDNF /ERK/CREB signaling. MOLECULAR MEDICINE REPORTS 11: 2927-2934, 2015 12. Fuchao Chen1,Baoxia Fang1,Peng Li1,Xuesong Zhu1, Benhong Zhou2,3. Physico-chemical stability of butorphanol-tramadol and butorphanol-fentanyl patient-controlled analgesia infusion solutions over 168 hours. Pharmazie 69: 585–588 (2014) 13. Gang Liu,Hui Wang,Benhong Zhou, Xianxi Guo,Xianming Hu. Compositional analysis and nutritional studies of Tricholoma matsutake collected from Southwest China. Journal of Medicinal Plants Research. 2010,4(12).1222-122 (SCI) 14. Gang Liu,Hui Wang,Benhong Zhou,Yi Luo,Xianming Hu. Simultaneous determination of 6 active components in traditional Chinese medicine “KANGXIN” tablets by RP-HPLC-DAD. Journal of Medicinal Plants Research. 2010,4(4).298-303 (SCI) 15.Yun Wanga ,1, Zhenpeng Qiub,1, Benhong Zhouc, Cong Liub, Jinlan Ruand, Qiujin Yanb, Jianming Liaob, Fan Zhub., In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells. Toxicology in Vitro 29 (2015) 1107–1115 16. Benhong Zhoua, Jing Wanga, Guohua Zhengb, Zhenpeng Qiuc, *Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21. Food and Chemical Toxicology, 2016,97:375-384