个人简介
1988年至2005年武汉大学人民医院工作 2005年获武汉大学生命科学学院生物化学与分子生物学专业博士学位 2008年至2009年加拿大University of Waterloo博士后 2006年至今武汉大学药学院工作
研究领域
天然药物活性成分及作用机制;抗肿瘤药物作用机制;药物新制剂
近期论文
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1. Yu J, Bao W, Lei J (2013). Emodin regulates apoptotic pathway in human liver cancer cells. Phytotherapy Research 27(2): 251–257. 2. Luo T, Yu J(共同第一作者), Nguyen J, Wang CR, Bristow RG, Jaffray DA, Zhou XZ, Lu KP, Lu QB (2012). Electron transfer-based combination therapy of cisplatin with tetramethyl-p-phenylenediamine for ovarian, cervical, and lung cancers. Proc. Natl. Acad. Sci. USA (PNAS)109:10175–10180. 3. Ding C, Zhang W, Li J, Lei J, Yu J*(2013) . Cytotoxic constituents of ethyl acetate fraction fromDianthus superbus. Natural Product Research (DOI:10.1080/14786419.2012.763127) 4. Yu J, Yin Y, Lei J, Zhang X, Chen W, Ding C, Wu S, He X, Liu Y, Zou G (2012). Activation of apoptosis by ethyl acetate fraction of ethanol extract of Dianthus superbus in HepG2 cell line.Cancer Epidemiology 36: e40–e45. 5. Lei J, Yu J*, Yin Y, Liu Y, Zou G (2012). Alantolactone induces activation of apoptosis in human hepatoma cells. Food and Chemical Toxicology 50: 3313–3319. 6. Yu J, Lei J, Zhang X, Yu H, Tian D, Liao Z, Zou G (2011). Anticancer, antioxidant and antimicrobial activities of the essential oil of Lycopus lucidus Turcz. var. hirtus Regel. Food Chemistry 126: 1593–1598. 7. Lei J, Yu J*, Yu H, Liao Z. Composition, cytotoxicity and antimicrobial activity of essential oil from Dictamnus dasycarpus. Food Chemistry, 2008, 107: 1205–1209. 8. Yu J, Liu H, Tian D, Liu Y, Lei J, Zou G (2007). Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells.Hepatology Research 37: 68–76. 9. Yu J, Liu H, Lei J, Tan W, Hu X, Zou G (2007). Antitumor activity of chloroform fraction ofScutellaria barbata and its active constituents. Phytotherapy Research 21: 817–822. 10. Yu J, Liao Z, Lei J, Hu X (2007). Antioxidant and cytotoxic activities of various fractions of ethanol extract of Dianthus superbus. Food Chemistry 104: 1215-1219. 11. Yu J, Liao Z, Cai X, Lei J, Zou G (2007). Composition, antimicrobial activity and cytotoxicity of essential oils from Aristolochia mollissima. Environmental Toxicology and Pharmacology 23: 162–167.