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Kwok, S.W., Zhang, L., Grimster, N.P., Fokin, V.V. Catalytic Asymmetric Transannulation of NH-1,2,3-Triazoles with Olefins. Angew. Chem., Int. Ed. 2014, Ahead of Print. doi:10.1002/anie.201306706
Sit, R.K., Fokin, V.V., Amitai, G., Sharpless, K.B., Taylor, P., Radic, Z. Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification. J. Med. Chem. 2014, 57, 1378-1389. doi:10.1021/jm401650z
Chuprakov, S., Worrell, B.T., Selander, N., Sit, R.K., Fokin, V.V. Stereoselective 1,3-Insertions of Rhodium(II) Azavinyl Carbenes. J. Am. Chem. Soc. 2014, 136, 195-202. doi:10.1021/ja408185c
Worrell, B.T., Ellery, S.P., Fokin, V.V. Copper(I)-Catalyzed Cycloaddition of Bismuth(III) Acetylides with Organic Azides: Synthesis of Stable Triazole Anion Equivalents. Angew. Chem., Int. Ed. 2013, 52, 13037-13041. doi:10.1002/anie.201306192 (C&EN News of the Week; TSRI News&Views)
Sanphanya, K., Wattanapitayakul, S.K., Phowichit, S., Fokin, V.V., Vajragupta, O. Novel VEGFR-2 Kinase Inhibitors Identified by the Back-to-Front Approach. Bioorg. Med. Chem. Lett. 2013, 23, 2962-2967. doi:10.1016/j.bmcl.2013.03.042
Worrell, B.T., Malik, J.A., Fokin, V.V.Direct Evidence of a Dinuclear Copper Intermediate in Cu(I)-Catalyzed Azide-Alkyne Cycloadditions. Science (Washington, DC, U. S.) 2013, 340, 457-460. doi: 10.1126/science.1229506
Rillahan, C.D., Schwartz, E., Rademacher, C., McBride, R., Rangarajan, J., Fokin, V.V., Paulson, J.C. On-Chip Synthesis and Screening of a Sialoside Library Yields a High Affinity Ligand for Siglec-7. ACS Chem. Biol. 2013, 8, 1417-1422. doi:10.1021/cb400125w
Radic, Z., Sit, R.K., Garcia, E., Zhang, L., Berend, S., Kovarik, Z., Amitai, G., Fokin, V.V., Barry Sharpless, K., Taylor, P. Mechanism of Interaction of Novel Uncharged, Centrally Active Reactivators with OP-hAChE Conjugates. Chem.-Biol. Interact. 2013, 203, 67-71. doi:10.1016/j.cbi.2012.08.014
Miyamoto, Y., Kalisiak, J., Korthals, K., Lauwaet, T., Cheung, D.Y., Lozano, R., Cobo, E.R., Upcroft, P., Upcroft, J.A., Berg, D.E., Gillin, F.D., Fokin, V.V., Sharpless, K.B., Eckmann, L. Expanded Therapeutic Potential in Activity Space of Next-Generation 5-Nitroimidazole Antimicrobials with Broad Structural Diversity. Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 17564-17569, S17564/17561-S17564/17127. doi:10.1073/pnas.1302664110
Malysheva, Y.B., Buchvalova, S.Y., Svirshchevskaya, E.V., Fokin, V.V., Fedorov, A.Y. Negishi Cross-Coupling Reaction as a Route to Isocombretastatins. Synlett 2013, 24, 1772-1776. doi:10.1055/s-0033-1339334
Zibinsky, M., Fokin, V.V. Sulfonyl-1,2,3-Triazoles: Convenient Synthones for Heterocyclic Compounds. Angew. Chem., Int. Ed. 2013, 52, 1507-1510. doi:10.1002/anie.201206388
Kovarik, Z., Macek, N., Sit, R.K., Radic, Z., Fokin, V.V., Barry Sharpless, K., Taylor, P. Centrally Acting Oximes in Reactivation of Tabun-Phosphoramidated AChE. Chem.-Biol. Interact. 2013, 203, 77-80. doi:10.1016/j.cbi.2012.08.019
Fraser, B.H., Hamilton, S., Krause-Heuer, A.M., Wright, P.J., Greguric, I., Tucker, S.P., Draffan, A.G., Fokin, V.V., Sharpless, K.B. Synthesis of 1,4-Triazole Linked Zanamivir Dimers as Highly Potent Inhibitors of Influenza A and B. MedChemComm 2013, 4, 383-386. doi:10.1039/c2md20300f
Chuprakov, S., Kwok, S.W., Fokin, V.V. Transannulation of 1-Sulfonyl-1,2,3-Triazoles with Heterocumulenes. J. Am. Chem. Soc. 2013, 135, 4652-4655. doi:10.1021/ja400350c
Yamauchi, J.G., Gomez, K., Grimster, N., Dufouil, M., Nemecz, A., Fotsing, J.R., Ho, K.-Y., Talley, T.T., Sharpless, K.B., Fokin, V.V., Taylor, P. Synthesis of Selective Agonists for the a7 Nicotinic Acetylcholine Receptor with in Situ Click-Chemistry on Acetylcholine-Binding Protein Templates. Mol. Pharmacol. 2012, 82, 687-699. doi:10.1124/mol.112.080291
Worrell, B.T., Hein, J.E., Fokin, V.V. Halogen Exchange (Halex) Reaction of 5-Iodo-1,2,3-Triazoles: Synthesis and Applications of 5-Fluorotriazoles. Angew. Chem., Int. Ed. 2012, 51, 11791-11794. doi:10.1002/anie.201204979
Selander, N., Worrell, B.T., Fokin, V.V. Ring Expansion and Rearrangements of Rhodium(II) Azavinyl Carbenes. Angew. Chem., Int. Ed. 2012, 51, 13054-13057. doi:10.1002/anie.201207820
Selander, N., Worrell, B.T., Chuprakov, S., Velaparthi, S., Fokin, V.V. Arylation of Rhodium(II) Azavinyl Carbenes with Boronic Acids. J. Am. Chem. Soc. 2012, 134, 14670-14673. doi:10.1021/ja3062453
Selander, N., Fokin, V.V. Rhodium(II)-Catalyzed Asymmetric Sulfur(VI) Reduction of Diazo Sulfonylamidines. J. Am. Chem. Soc. 2012, 134, 2477-2480. doi:10.1021/ja210180q
Sanphanya, K., Wattanapitayakul, S.K., Prangsaengtong, O., Jo, M., Koizumi, K., Shibahara, N., Priprem, A., Fokin, V.V., Vajragupta, O. Synthesis and Evaluation of 1-(Substituted)-3-Prop-2-Ynylureas as Antiangiogenic Agents. Bioorg. Med. Chem. Lett. 2012, 22, 3001-3005. doi:10.1016/j.bmcl.2012.02.029