逯杨 - 武汉大学 - 生命科学学院

个人简介

学习经历： 2002－2008 中科院上海生命科学研究院生物化学与细胞生物学研究所，博士 1998－2002 吉林大学生物化学系，学士主要工作经历与任职情况： 2016－至今武汉大学生命科学学院，研究员，博士生导师 2013－2015 加州大学欧文分校医学院，研究助理 2008－2013 加州大学欧文分校医学院，博士后

研究领域

1）宿主内环境因子对白念珠菌形态及致病性的调控机理；2）真菌的营养代谢途径；3）白念珠菌从共生菌到致病菌的转换机理；4）致病真菌激活宿主细胞免疫应答的分子机制。实验室的长期目标是揭示白念珠菌和其它真菌的致病机理，为真菌系统性感染的药物研发和疾病诊断提供新的途径和靶标。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Yang Lu, Chang Su, and Haoping Liu. (2014) Candida albicans hyphal initiation and elongation. Trends in Microbiology 22(12): 707-14. 2. Yang Lu*, Chang Su*, Ohimai Unoje, and Haoping Liu. (2014) Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. Proc Natl Acad Sci U S A 111(5): 1975-80. (* equal contribution) 3. Yang Lu, Chang Su, Norma V. Solis, Scott G. Filler, and Haoping Liu. (2013) Synergistic regulation of hyphal elongation by hypoxia, CO2, and nutrient conditions controls the virulence of Candida albicans. Cell Host & Microbe 14(5): 499-509. 4. Chang Su*, Yang Lu*, and Haoping Liu. (2013) Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity. Molecular Biology of the Cell 24(3): 385-97. (* equal contribution) 5. Yang Lu, Chang Su, and Haoping Liu. (2012) A GATA transcription factor recruits Hda1 in response to reduced Tor1 signaling to establish a hyphal chromatin state in Candida albicans. PLoS Pathogens 8(4): e1002663. 6. Yang Lu, Chang Su, Allen Wang, and Haoping Liu. (2011) Hyphal development in Candida albicans requires two temporally linked changes in promoter chromatin for initiation and maintenance. PLoS Biology 9(7): e1001105. 7. Allen Wang, Prashna Pala Raniga, Shelley Lane, Yang Lu, and Haoping Liu. (2009) Hyphal chain formation in Candida albicans: Cdc28-Hgc1 phosphorylation of Efg1 represses cell separation genes. Molecular and Cellular Biology 29(16): 4406-16. 8. Chang Su, Yandong Li, Yang Lu, and Jiangye Chen. (2009) Mss11, a transcriptional activator, is required for hyphal development in Candida albicans. Eukaryotic Cell 8(11):1780-91. 9. Yang Lu, Chang Su, Xuming Mao, Prashna Pala Raniga, Haoping Liu, and Jiangye Chen. (2008) Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans. Molecular Biology of the Cell 19(10): 4260-72. 10. Fang Cao*, Shelley Lane*, Prashna Pala Raniga, Yang Lu, Zhou Zhou, Karalyn Ramon, Jiangye Chen, and Haoping Liu. (2006) The Flo8 transcription factor is essential for hyphal development and virulence in Candida albicans. Molecular Biology of the Cell 17(1): 295-307. (* equal contribution)