陈向东 - 武汉大学 - 生命科学学院

个人简介

先后获得武汉大学微生物学专业学士和硕士学位后于1988年留校任教；1997年晋升为副教授；2002年在职获得博士学位；2004年晋升为教授，2005年遴选为博士生导师；曾赴美国、日本的多所高校交流访问；现为中国微生物学会常务理事、“微生物学通报”杂志副主编；“生物资源”杂志编委会副主任；教育部大学生物学课程教学指导委员会秘书长；中国微生物学会教学工作委员会主任；中国遗传学会微生物遗传学专业委员会副主任；中国微生物学会基础微生物学专业委员会委员、中国微生物学会分子微生物学与生物工程专业委员会委员、湖北省暨武汉微生物学会常务理事、湖北省遗传学会常务理事；国家级教学团队负责人；湖北名师奖获得者；

研究领域

1、通过自然遗传转化过程进行的细菌细胞间水平基因转移；2、极端嗜盐古菌溶源病毒与宿主细胞间的相互作用机制；3、细菌黑色素的基础和应用研究，特别是中间气单胞菌WS菌株的黑色素形成分子机理解析和应用开发；

近期论文

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1. Yunqian Qiao, Jiao Wang, He Wang, Baozhong Chai, Chufeng Rao, Xiangdong Chen*, Shishen Du*(2019),,4-hydroxyphenylpyruvate dioxygenase thermolability is responsible for temperature-dependent melanogenesis in Aeromonas salmonicida subsp. salmonicida, Appl. Environ, Microbiol. 85(1), e01926-18 2. Xiaoming Zhang, Tingting Jin, Liping Deng, Chao Wang, Yuhua Zhang, Xiangdong Chen* (2018), Stress-Induced, Highly Efficient, Donor Cell-Dependent Cell-toCell Natural Transformation in Bacillus subtilis, J Bacteriol 200(17): e00267-18. 3. Ruili Zhao, Rui Zhao, Yishuai Tu, Xiaoming Zhang, Liping Deng, Xiangdong Chen* (2018) A novel α-galactosidase from the thermophilic probiotic Bacillus coagulans with remarkable protease-resistance and high hydrolytic activity. PLoS ONE 13(5): 1-16,e0197067 4. Jiao Wang, Yingchun Liu, Ying Liu, Kaixin Du, Shuqi Xu, Yuchen Wang, Mart Krupovic, Xiangdong Chen* (2018) A novel family of tyrosine integrases encoded by the temperate pleolipovirus SNJ2, Nucleic Acids Res, 46(5):2521–2536, https://doi.org/10.1093/nar/gky005 5. Yuchen Wang, Beibei Chen, Mengzhuo Cao, Linshan Sima, David Prangishvili, Xiangdong Chen*, Mart Krupovic* (2018) Rolling-circle replication initiation protein of haloarchaeal sphaerolipovirus SNJ1 is homologous to bacterial transposases of the IS91 family insertion sequences, J Gen., Virol, 99: 416-421, doi: 10.1099/jgv.0.001009 6. Yuchen Wang, Beibei Chen, Linshan Sima, Mengzhuo Cao, and Xiangdong Chen* (2017) Construction of Expression Shuttle Vectors for the Haloarchaeon Natrinema sp. J7 Based on Its Chromosomal Origins of Replication，Archaea，Volume 2017, Article ID 4237079, 11 pages 7. Baozhong Chai, Yunqian Qiao, He Wang, Xiaoming Zhang, Jiao Wang,Choushi Wang, Ping Zhou and Xiangdong Chen* (2017) Identification of YfiH and the Catalase CatA As Polyphenol Oxidases of Aeromonas media and CatA as a Regulator of Pigmentation by Its Peroxyl Radical Scavenging Capacity，Fron., Microbiol. 8:1939. doi: 10.3389/fmicb.2017.01939，12pages 8. Yuchen Wang, Linshan Sima, Jie Lv, Suiyuan Huang, Ying Liu, Jiao Wang, Mart Krupovic, Xiangdong Chen*，(2016), Identification, characterization and application of the replicon region of the halophilic temperate sphaerolipovirus SNJ1. J Bacteriol., 198(4):1952-1964 9. Salla T. Jaakkola, Friedhelm Pfeiffer,Janne J. Ravantti, Qinggong Guo,Ying Liu, Xiangdong Chen, Hongling Ma, Chunhe Yang,Hanna M. Oksanen , Dennis H. Bamford*，(2016), The complete genome of a viable archaeum isolated from 123-million-year-old rock salt, Environ. Microbiol. 18(2), 565–579