熊海蓉 - 武汉大学 - 基础医学院

个人简介

6、学习经历： 1997.9-2002.6 武汉大学医学院, 医学学士 2002.9-2009.6 武汉大学基础医学院, 病原生物学系,博士 2005.6-2009.3 Medical College of Georgia,联合培养博士 7、主要工作经历与任职： 2009.7-2012.11 武汉大学基础医学院讲师 2012.12-至今武汉大学基础医学院副教授

研究领域

从事病毒感染的致病机制与防治技术研究，主要包括人类免疫缺陷病毒（HIV）和汉坦病毒（HV）等多种病毒的感染与免疫机制研究、人类重要病毒性传染病（HFRS、AIDS等）的分子流行病学研究、抗病毒药物研究（流感病毒、疱疹病毒、柯萨奇病毒、呼吸道合胞病毒、轮状病毒、EV71、汉坦病毒等常见病毒）。

近期论文

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1. Li MK, Liu YY, Wei F, Shen MX, Zhong Y, Li S, Chen LJ, Ma N, Liu BY, Mao YD, Li N, Hou W, Xiong HR*, Yang ZQ*. Antiviral activity of arbidol hydrochloride against herpes simplex virus type in vitro and in vivo. International Journal of Antimicrobial Agents. 2018 Jan;51(1):98-106 (co-corresponding author) 2. Chen QZ, Luo F, Lu MX, Li N, Teng Y, Huang QL, Zhu N, Wang GY, Yue M, Zhang Y, Feng Y, Xiong HR*, Hou W*. HTNV-induced upregulation of miR-146a in HUVECs promotes viral infection by modulating pro-inflammatory cytokine release. Biochemical and Biophysical Research Communications. 2017 Nov 4;493(1):807-813. ( co-corresponding author) 3. Chen XP§, Xiong HR§, Zhu N, Chen QZ, Wang H, Zhong CJ, Wang MR, Lu S, Luo F, Hou W*. Lack of association between integrin αvβ3 gene polymorphisms and hemorrhagic fever with renal syndrome in Han Chinese from Hubei, China. Virologica Sinica. 2017 Feb;32(1):73-79.(co-first author) 4. Liu YY, Chen LJ, Zhong Y, Shen MX, Ma N, Liu BY, Luo F, Hou W, Yang ZQ, Xiong HR*. Specific interference shRNA-expressing plasmids inhibit Hantaan virus infection in vitro and in vivo. Acta Pharmacologica Sinica. 2016 Apr;37(4):497-504 5. Xiong HR, Zhang YH, Deng Kan, Liu Q, Liu YY, Luo F, Hou W, Yang ZQ*. Antiviral activity and mechanism of action of arbidol against Hantaan virus infection. Tropical Journal of Pharmaceutical Research. 2016; 15 (7): 1439-1445 6. Liu Q§, Xiong HR§, Lu L, Liu YY, Luo F, Hou W, Zhan-Qiu Yang. Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection. Acta Pharmacologica Sinica. 2013 Aug 5;34(8):1075-83 (co-first author) 7. Xiong HR, Shen YY, Lu L, Hou W, Luo F, Xiao H, Yang ZQ. The Inhibitory Effect of Rheum palmatum Against Coxsackievirus B(3)in Vitro and in Vivo. The American Journal of Chinese Medicine. 2012;40(4):801-12. 8. Xiong HR, Lee RJ, Haura EB, Edward JG, Dynan WS, Li S. Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. International Journal of Radiation Oncology Biology Physics. 2012;Jul 1;83(3):1023-30. 9. Xiong HR, Li Q, Chen W, Liu DY, Ling JX, Liu J, Liu YJ, Zhang Y, Yang ZQ. Specific Humoral Reaction of Hemorrhagic Fever with Renal Syndrome (HFRS) Patients in China to Recombinant Nucleocapsid Proteins from European Hantaviruses. European journal of clinical microbiology & infectious diseases. 2011 May;30(5):645-51. 10. Xiong HR, Luo J, Hou W, Xiao H, Yang ZQ. The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo. Journal of ethnopharmacology, 2011 Jan 27;133(2):718-23.