何春江 - 武汉大学 - 基础医学院

个人简介

6、学习经历： 2003.9 – 2008.6：武汉大学生命科学学院，细胞生物学，博士 1999.9 – 2003.6：武汉大学生命科学学院，生物技术，学士 7、主要工作经历与任职 2009.2-2012.4 芝加哥大学医学院血液与肿瘤部博士后导师：Jianjun Chen & Janet D. Rowley 2012.5-2013.12 斯坦福大学医学院心血管与干细胞研究所博士后导师：Joseph Wu 2014.3至今武汉大学基础医学院副教授，博士生导师

研究领域

开发生物信息学工具和数据库，结合实验方法，研究白血病和癌症转录组及免疫组的调控与功能，筛选新的药物靶点和免疫治疗靶标。

近期论文

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1.Xia S*, Feng J*, Chen K*, Ma Y, Gong J, Cai F, Jin Y, Gao Y, Xia L, Chang H, Wei L, Han L#,He C#. CSCD: A database for cancer-specific circular RNAs.Nucleic Acids Research. 2017 Sep 28. doi: 10.1093/nar/gkx863. 2.Feng J*, Xiang Y*, Xia S*, Liu H, Wang J, Ozguc F, Lei L, Kong R, Diao L,He C#,Han L#. CircView: a visualization and exploration tool for circular RNAs.Briefings in Bioinformatics. 2017. doi: 10.1093/bib/bbx070. 3.Lei L*, Xia S*, Liu D*, Li X*, Feng J, Zhu Y, Hu J, Xia L, Guo L, Chen F, Cheng H, Chen K, Hu H, Chen X, Li F, Zhong S, Mittal N, Yang G, Qian Z, Han L#,He C#.Genome-wide characterization of lncRNAs in acute myeloid leukemia.Briefings in Bioinformatics. 2017 Feb 15. doi: 10.1093/bib/bbx007. 4.Xia S*, Feng J*, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L#,He C#. Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes.Briefings in Bioinformatics. 2016 Aug 20. pii: bbw081. 5.He C*#, Hu H*, Wilson KD*, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC#. Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart.Circulation Cardiovascular Genetics. 2016 Feb 19. pii: CIRCGENETICS.115.001264. 6.Li Z*, Herold T*,He C*, Valk PJ, Chen P, Jurinovic V, Mansmann U, Radmacher MD, Maharry KS, Sun M, Yang X, Huang H, Jiang X, Sauerland MC, Büchner T, Hiddemann W, Elkahloun A, Neilly MB, Zhang Y, Larson RA, Le Beau MM, Caligiuri MA, Döhner K, Bullinger L, Liu PP, Delwel R, Marcucci G, Lowenberg B, Bloomfield CD, Rowley JD, Bohlander SK, Chen J. Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.Journal of Clinical Oncology. 2013 Mar 20;31(9):1172-81. doi: 10.1200/JCO.2012.44.3184. 7.He C*, Li Z*, Chen P*, Huang H, Hurst LD, Chen J. Young intragenic miRNAs are less coexpressed with host genes than old ones: implications of miRNA-host gene coevolution.Nucleic Acids Research. 2012 May;40(9):4002-12. doi: 10.1093/nar/gkr1312. 8.Mi S*, Li Z*, Chen P*,He C*, Cao D, Elkahloun A, Lu J, Pelloso LA, Wunderlich M, Huang H, Luo RT, Sun M, He M, Neilly MB, Zeleznik-Le NJ, Thirman MJ, Mulloy JC, Liu PP, Rowley JD, Chen J. Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia.Proc Natl Acad Sci U S A.2010 Feb 23;107(8):3710-5. doi: 10.1073/pnas.0914900107. 9.He C*, Zhou F, Zuo Z, Cheng H, Zhou R. A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis.PLoS One.2009;4(3):e4732. doi: 10.1371/journal.pone.0004732. 10.He C*, Cheng H, Zhou R. GATA family of transcription factors of vertebrates: phylogenetics and chromosomal synteny.Journal of Biosciences.2007 Dec;32(7):1273-80. 11.He C*, Zuo Z, Chen H, Zhang L, Zhou F, Cheng H, Zhou R. Genome-wide detection of testis- and testicular cancer-specific alternative splicing.Carcinogenesis.2007 Dec;28(12):2484-90.