陈洪雷 - 武汉大学 - 基础医学院

个人简介

6、学习经历： 2012,5-2013,8 美国Rush大学医学中心生物化学系博士后 2005, 9-2010,6 武汉大学人民医院内科学博士 1999, 9-2002, 7 武汉大学基础医学院病理学与病理生理学硕士 1994, 9-1999, 7 原咸宁医学院临床医学系本科 7、主要工作经历与任职： 2018,6-2019,5 美国MD Anderson肿瘤中心访问副教授 2015,9-2015,12 日本福岛医科大学病理学系访问学者 2014,9-2015,4 复旦大学妇产科医院病理科进修学习 2010-至今武汉大学基础医学院病理学与病理生理学系副教授硕导 2005-2010 武汉大学基础医学院病理学与病理生理学系讲师 2002-2005 武汉大学基础医学院病理学与病理生理学系助教

研究领域

主要研究方向是肿瘤微环境中的能量代谢和自噬以及肿瘤免疫在肿瘤特别是肺癌侵袭转移中的作用机制。

近期论文

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1. Liu J, Lu F, Gong Y, Zhao C, Pan Q, Ballantyne S, Zhao X, Tian S, Chen H*. High expression of synthesis of cytochrome c oxidase 2 and TP53-induced glycolysis and apoptosis regulator can predict poor prognosis in human lung adenocarcinoma. Hum Pathol. 2018 Apr 7. 77:54-62. 2. Wu J, Di D, Zhao C, Liu Y, Chen H, Gong Y, Zhao X, Chen H*. Role of glioma-associated GLI1 oncogene in carcinogenesis and cancer targeted therapy. Current Cancer Drug Targets, 2018, 18:558-566. 3. Zhao C, Wang A, Lu F, Chen H, Fu P, Zhao X, Chen H*. Overexpression of JAM-A and EphB2 predict poor survival in lung adenocarcinoma patients. Tumor Biology, 2017, 39(2):1-9. 4. Fu P, Chen F, Pan Q, Zhao X, Zhao C, Cho WC*, Chen H*. The different functions and clinical significances of caveolin-1 in the human adenocarcinomas and squamous cell carcinomas. OncoTargets and Therapy. 2017, 10:819-835. 5. Zhao C, Lu F, Chen H, Zhao F, Zhu Z, Zhao X, Chen H*. Clinical significance of circulating miRNA detection in lung cancer. Med Oncol. 2016 May;33(5):41-50. 6. Qu Y, Zhang Q, Pan Q, Zhao X, Huang Y, Chen F, Chen H*. Quantum dots immunofluorescence histochemical detection of EGFR gene mutations in the non-small cell lung cancers using mutation-specific antibodies. Int J Nanomed, 2014,9(1):5771-8. 7. Chen H, Wu S, Lu R, Zhang Y, Zheng Y, Sun J*. Pulmonary permeability assessed by fluoresce-labeled dextran instilled intranasally into mice with LPS-induced acute lung injury. PLoS One, 2014, 9(7): e101925. 8. He Y, Zhao X, Subahan NR, Fan L, Gao J, Chen H*. The Prognostic Value of Autophagic Related Markers Beclin-1 and Light Chain 3 in Cancers: A Systematic Review and Meta-analysis. Tumor Biology, 2014, 35(8):7317-26. 9. Zhao X, He Y, Gao J, Fan L, Li Z, Yang G, Chen H*. Caveolin-1 expression level in cancer associated fibroblasts predicts outcome in gastric cancer. PLoS One, 2013, 8(2):e59102 10. Zhao X, He Y, Chen H*. Autophagic tumor stroma: Mechanisms and roles in tumor growth and progression. Int J Cancer. 2013, 132(1):1-8