个人简介
学习经历: 2003/09-2006/06,第二军医大学,基础医学院生理学教研室,博士 1996/09-1999/06 武汉大学,医学院病理学与病理生理学系,硕士 1982/09-1987/06 武汉大学,医学院(原湖北医科大学)医学系,学士 主要工作经历与任职: 2013/10-2013/12 日本福岛医学大学,药理学系,访问学者 2008/11-现在 武汉大学,基础医学院生理系,教授 1999/11-2008/10 武汉大学,基础医学院生理系,副教授 1987/07-1996/08 武汉大学,医学院实验中心,助教,讲师
研究领域
小分子生物活性物质在心血管损伤性疾病中的作用,尤其是气体信号分子硫化氢对心肌缺血、动脉粥样硬化血管钙化等疾病的保护作用及其对心血管疾病发病过程中内质网应激的调控作用研究。
近期论文
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[1]Antagonism of endothelin-1 inhibits hypoxia-induced apoptosis in cardiomyocytes. Can J Physiol Pharmacol. 2008;86(8):536-40. [2] H2S protects myocardium against ischemia/reperfusion injury and its effect on c-Fos protein expression in rats. Acta Physiologica Sinica. 2008; 60(2):221-7. [3]Salusins protect neonatal rat cardiomyocytes from serum deprivation-induced celldeath through upregulation of GRP78. J Cardiovasc Pharmacol. 2006; 48(2):41-6. [4] Angelica protects human vascular endothelial cells from the oxidization of low-density lipoprotein in vitro. Clin Hemorheol Microcirc. 2000; 22(4):317-23. [5]Delayed cytoprotection induced by hypoxic preconditioning in cultured neonatal rat cardiomyocytes: Role of GRP78. Life Sciences 2007, 81:1042-1049. [6] Arrhythmogenic action of endothelin-1(1-31) through conversion toendothelin-1(1-21). Exp Biol Med (Maywood). 2006;231(6):937-41. [7] Blood pressure responses of endothelin-1 1-31 within the rostral ventrolateralmedulla through conversion to endothelin-1 1-21. J Cardiovasc Pharmacol. 2005,46(6):823-9. [8] Experimental study of the anti-atherogenesis effects and mechanisms of Chinese medicine Angelica. Clin Hemorheol Microcirc. 2000; 22(4):305-10. [9] H2S post-conditioning protect rat myocardium from ischemia reperfusion injury involved in endoplasmic reticulum stress. Nitric Oxide: Biology and Chemistry Journal. 2012,27:s26-27 [10]Cardioprotection of H2S against ischemia reperfusion injury through inhibiting endoplasmic reticulum stress -induced apoptosis. Acta Physiologica Sinica. 2012, 64(suppl.1): 114