彭碧文 - 武汉大学 - 基础医学院

个人简介

学习经历： 1992.9-1997.7 湖北医科大学临床专业临床医学学士学位 1997.9-2000.7 武汉大学医学院生理专业生理学硕士学位 2000.9-2003.7 武汉大学医学院病原生物学博士学位 2004.12-2007.2 美国德州大学医学中心药理学系博士后主要工作经历与任职： 1997.7-2002.10 武汉大学医学院生理学系助教 2002.10-2004.11 武汉大学医学院生理学系讲师 2007.3-2008.10 武汉大学医学院生理学系讲师 2008.10-2013.10 武汉大学医学院生理学系副教授 2013.11-至今武汉大学医学院生理学系教授

研究领域

主要研究领域是胶质细胞对突触活性的影响及机制，尤其小胶质细胞在突触形成及神经元活性中的作用，并探讨小胶质细胞释放活性物质的机理，从而为新生儿癫痫、缺氧缺血及热应激损伤中的机制提供依据

近期论文

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1. Luo WD, Min JW, Huang WX, Wang X, Peng YY, Han S, Yin J, Liu WH, He XH, Peng BW*. Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1. Journal of Neuroinflammation. 2018，15(1):186. (2区, SCI=5.193) 2. Kong WL, Peng YY, Peng BW*. Modulation of neuroinflammation: Role and therapeutic potential of TRPV1 in the neuro-immune axis. Brain Behavior and Immunity. 2017，64:354-366. (2区, SCI=5.96) 3. Hu JJ, Yang XL, Luo WD, Han S, Yin J, Liu WH, He XH, Peng BW*. Bumetanide reduce the seizure susceptibility induced by pentylenetetrazol via inhibition of aberrant hippocampal neurogenesis in neonatal rats after hypoxia-ischemia. Brain Research Bulletin, 2017, 130C: 188-199. (3区, SCI=3.3) 4. Min JW, Hu JJ, He M, Sanchez RM, Huang WX, Liu YQ, Bsoul N, Han S, Yin J, Liu WH, He XH*, Peng BW*. Vitexin reduces hypoxia-ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model. Neuropharmacology, 2015, 99: 38-50. (2区，SCI=5.1) 5. Huang WX, Yu F, Sanchez RM, Liu YQ, Min JW, Hu JJ, Bsoul N, Han S, Yin J, Liu WH, He XH*, Peng BW*. TRPV1 promotes the occurrence of repetitive febrile seizures by increasing the secretion of pro-inflammatory cytokines in the immature brain. Brain Behavior and Immunity. 2015, 48:68-77. (2区，SCI=5.87) 6. Liu YQ, Huang WX, Sanchez RM, Min JW, Hu JJ, He XH, Peng BW*. Regulation of Kv4.2 A-Type Potassium Channels in HEK-293 Cells by Hypoxia. Frontiers in Cellular Neuroscience. 2014, 8: 329 (2区，SCI=4.6) 7. Liu YQ, Yu F, Liu WH, He XH, Peng BW*. Dysfunction of hippocampal interneurons in epilepsy. Neuroscience Bulletin. 2014, 30(6):985-998. (SCI=2.32) 8. Kong WL, Min JW, Liu YL, Li JX, He XH and Peng BW*. Role of TRPV1 in susceptibility of PTZ-induced seizure following repeated hyperthermia challenges in neonatal mice. Epilepsy & Behavior. 2014, 31:276-280. (SCI=2.3) 9. Xu J, Fan Y, Li L, Qiu Y, Wang Z, Han S, Yin J, Liu W, Peng B* and He X*. Hyperthermia-induced seizures: Development of hyperthermia-prone and hyperthermia-resistant rats. Epilepsy Research. 2013, 106 (3): 311-317 (SCI=2.3) 10. Peng BW*, Justice J, He XH and Sanchez RM*. Decreased A-currents in hippocampal dentate granule cells after seizure-inducing hypoxia in the immature rat. Epilepsia. 2013, 54: 1223-1231 (2区，SCI=4.7）