个人简介
学习经历: 2002.09 ~ 2006.11 武汉大学医学部药理学系硕博连读,获医学博士学位 1994.09 ~ 1999.07 武汉大学(原湖北医科大学),获医学学士学位 主要工作经历与任职: 20016.12 ~ 至今 武汉大学基础医学院药理系,教授、博导 2012.09 ~ 2013.09 美国贝勒医学院儿童营养研究中心,访问学者 2009.12 ~ 2016.11 武汉大学基础医学院药理系,副教授、硕导 2006.12 ~ 2009.11 武汉大学基础医学院药理系,讲师 2005. 03 ~ 2006.09 军事医学科学院基础医学研究所,访问学者 1999.07 ~ 2002.08 武汉大学中南医院工作
研究领域
1)肥胖及其并发症的发生机制及药物防治; 2)内分泌毒理与药物靶标研究;
近期论文
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1) Li GL, Chen HJ, Zhang WX, Tong Q, Yan YE*. Effects of maternal omega-3 fatty acids supplementation during pregnancy/lactation on body composition of the offspring: A systematic review and meta-analysis. Clin Nutr. 2018,37,1462-1473. 2) Zhang WX#, Li YP#, Fan J, Chen HJ, Li GL, Ouyang YQ, Yan YE*. Perinatal nicotine exposure increases obesity susceptibility by peripheral leptin resistance in adult female rat offspring. Toxicol Lett. 2018;283(2):91-99. 3) Fan J, Zhang WX, Rao YS, Xue JL, Wang FF, Zhang L, Yan YE*. Perinatal Nicotine Exposure Increases Obesity Susceptibility in Adult Male Rat Offspring by Altering Early Adipogenesis. Endocrinology, 2016,157(11):4276-86. 4) Fan J, Ping J, Xiang J, Rao YS, Zhang WX, Chen T, Zhang L, Yan YE*. Effects of prenatal and lactation nicotine exposure on glucose homeostasis, lipogenesis and lipid metabolic profiles in mothers and offspring. Toxicology Research, 2016, 5, 1318-28. 5) Zhang WX, Fan J, Ma J, Rao YS, Zhang L, Yan YE*. Selection of Suitable Reference Genes for Quantitative Real-Time PCR Normalization in Three Types of Rat Adipose Tissue. International Journal Of Molecular Sciences, 2016 22;17(6). pii: E968. 6) Liu L, Wang JF, Fan J, Rao YS, Liu F, Yan YE*, Wang H. Nicotine Suppressed Fetal Adrenal StAR Expression via YY1 Mediated-Histone Deacetylation Modification Mechanism. International Journal Of Molecular Sciences, 2016 3;17(9). pii: E1477. 7) Fan J, Ping J, Zhang WX, Rao YS, Liu HX, Zhang J, Yan YE*. Prenatal and lactation nicotine exposure affects morphology and function of brown adipose tissue in male rat offspring. Ultrastructural Pathology, 2016, 40(5):288-95. 8) Yan YE, Liu L(Co-first author), Wang JF, Liu F, Li XH, Qin HQ, Wang H*. Prenatal nicotinic exposure suppresses fetal adrenal steroidogenesis via steroidogenic factor 1 (SF-1) deacetylation. Toxicology and Applied Pharmacology, 2014, 277(3):231-41. 9) Feng JH, Yan YE(Co-first author), Liang G, Liu YS, Li XJ, Zhang BJ, Chen LB, Yu H, He XH, Wang H. Maternal and fetal metabonomic alterations in prenatal nicotine exposure-induced rat intrauterine growth retardation. Molecular and Cellular Endocrinology, 2014, 394(1-2):59-69.