个人简介
学习经历: 1996/09-2000/07,华中师范大学,生命科学学院,学士 2000/09-2003/07,华中师范大学,生命科学学院,硕士 2003/09-2006/07,中国疾病预防控制中心病毒病预防控制所,病毒病预防控制所,博士 主要工作经历与任职: 2007/05-2011/12,Creighton University School of Medicine,Department of Medical Microbiology and Immunology,博士后 2012/01-2012/05,Creighton University School of Medicine,Department of Medical Microbiology and Immunology,研究助理教授 2013/02-至今,武汉大学,基础医学院,教授
研究领域
致力于宿主细胞固有免疫在病原感染中的机制探讨,特别关注非编码RNA及RNA结合蛋白在病原生物与宿主细胞相互作用中的功能,并且与之相关的其在肝脏及胆管系统疾病中的功能探讨。
近期论文
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1.Lu Y, Liu X, Xie M, Liu M, Ye M, Li M, Chen XM, Li X, Zhou R*. The NF-κB-Responsive Long Noncoding RNA FIRRE Regulates Posttranscriptional Regulation of Inflammatory Gene Expression through Interacting with hnRNPU. J Immunol. 2017;199(10):3571-3582 2. Zijie Xia, Yajing Lu, Xiaoqing Li, Tiebo Mao, Xian-Ming Chen, Zhou R*. Upregulation of KSRP by miR-27b provides IFN-γ-induced post-transcriptional regulation of CX3CL1 in liver epithelial cells. Scientific Reports 2015, 5:17590. 3.Zhou R*, Feng Y, Chen XM*. Non-coding RNAs in epithelial immunity to Cryptosporidium infection. Parasitology. 2014, 141(10):1233-1243. 4.Zhou R, Gong AY, Chen D, Miller RE, Eischeid AN, Chen XM*. Histone deacetylases and NF-κB signaling coordinate expression of CX3CL1 in epithelial cells in response to microbial challenge by suppressing miR-424 and miR-503. PLoS One. 2013, 8(5):e65153. 5.Zhou R, Gong AY, Eischeid AN, Chen XM*. miR-27b regulates RNA stability to coordinate TLR4/NF-kappaB-mediated epithelial anti-C. parvum defense by targeting KSRP. PLoS Pathogen. 2012, 8: e1002702.