个人简介
2009- 迄今 重庆大学生物工程学院教授;重庆大学海外高层次引进人才 (2015.9迄今 重庆大学医院皮肤科周一,四 9-13:00皮肤科专家门诊(公益) 2008-迄今 兼巴斯大学博士副导师 2001 年获英国巴斯大学药理学系-光生物博士学位 1997-2008 英国巴斯大学药理学系博士;国王学院、UEA、巴斯大学任初级、高级博士后 1997 年获四川大学(原华西医大)临床医学6年制学士学位重庆市‘百人计划’特聘专家 1981-1997 华西医科大学(四川大学)临床医学系本科及四川省人民医院, 主治医师
研究领域
1. 研究紫外光(UVA和UVB)对人体皮肤细胞的作用,太阳光和人工紫外光源损伤皮肤和组织的具体机理,阐明细胞的防御机制。 2. 光治疗的相关机理,光动力治疗ALA -PDT、金属螯合疗法以及新型纳米材料/药物对皮肤的防护及治疗。光老化动物模型的研究。 4. 抗衰老,尤其是皮肤衰老产品研发。皮肤干细胞修复的药物及相关纳米材料的研发等。
近期论文
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Shiying Yang, Bin Zhou et.al , Jörg W. Bartsch,Julia Li Zhong.Nrf2- and Bach1 may play a role in the modulation of UVA-induced oxidative stress by acetyl-11-keto-β-boswellic acid (AKBA) in skin keratinocytes. 2016, Skin Pharmacology and Physiology Yan Wu,Julia Li Zhonget. al. Youliang Wang1#, Xiao Yang1#MicroRNA Let-7b inhibits keratinocyte migration in cutaneous wound healing by targeting IGF2BP2.Exp Dermatol,2016 Liu Y,Liu WB,Liu KJ,Ao L,Cao J,Zhong JL,Liu JY. Overexpression of miR-26b-5p regulates the cell cycle by targeting CCND2 in GC-2 cells under exposure to extremely low frequency electromagnetic fields.Cell Cycle.2016 Feb;15(3):357-67. Mingxing Lei, Xiangdong Lai, Xiufeng Bai, Weiming Qiu, Tian Yang,Xiaoling Liao, Cheng‑Ming Chuong, Li Yang,Xiaohua Lian*,Julia Li Zhong*.Prolonged overexpression of Wnt10b induces epidermal keratinocyte transformation through activating EGF pathway. Histochem Cell Biol. 2015 Sep;144(3):209-21DOI 10.1007/s00418-015-1330-6 Zhong JL(钟莉)*, Raval CM, Nisar MF, Bian CX, Zhang J, Tyrrell R. Development of Refractoriness of HO-1 Induction to a Second Treatment with UVA Radiation and the Involvement of Nrf2 in Human Skin Fibroblasts. Photochemistry and photobiology. Nov 2014;90(6):1340-1348. Nisar MF, Parsons KSG, Bian CX,Julia Li Zhong.* Invited Review:Induction of heme oxygenase-1 in skin fibroblasts by UVA: a potential phototherapeutic strategy of scleroderma. Photobiology and photochemistry. 2015, 91: 210–220. Huang X, Wang X, Wang S, Yang J,Zhong L, Pan J. UV and dark-triggered repetitive release and encapsulation of benzophenone-3 from biocompatible ZnO nanoparticles potential for skin protection.Nanoscale. 2013 Jun 21;5(12):5596-601. IF-6.9(JCR 1区) Raval CM,Zhong JL, Mitchell SA. Tyrrell RM. The role of Bach1 in ultraviolet a mediated human heme oxygenase 1 regulation in human skin fibroblasts.Free Radic Biol Med.2012, 52(1):227-36. Aroun A#,Zhong JL#, Tyrrell RM, Pourzand C. Iron, oxidative stress and the example of solar ultraviolet A radiation.PhotochemPhotobiolSci., 2012, 11(1):118-134. Chiang MY, Yangben Y, Lin NJ,Zhong JL, Yang L. Relationships among cell morphology, intrinsic cell stiffness and cell-substrate interactions.Biomaterials.2013 ;34(38):9754-62.