邓慧华 - 东南大学 - 生物科学与医学工程学院

个人简介

1998年于东南大学分子与生物分子电子学教育部重点实验室(吴健雄实验室)获得工学博士学位。1999年1月至2000年3月在日本Tohuku University(东北大学)从事博士后研究工作。2000年12月至2006年3月在日本产业技术综合研究所(AIST)进行纳米功能合成技术在分子传感器研究中的应用。目前集中于头发新型生物标记的开发、验证和应用，儿童发展的社会生物机制，动作意图理解等。主持或参与973、863、国家自然基金等国家级、省部级科研项目多项，以及NIH国际合作项目，获2000 中国高校科学技术奖自然科学奖二等奖、2001年全国百篇优秀博士论文奖、2005 年日本纳米技术国际博览会技术创新奖、2008年教育部新世纪优秀人才支持计划。自2012年以来，通过单胺类神经递质，以及HPA轴、HPG轴和内源性大麻素系统的激素评估儿童青少年的社会情绪能力发展。开发头发新型生物标记的检测技术，验证这些新型生物标记的可靠性，探索其在青少年的抑郁、焦虑等负性情绪、工作应激等慢性应激、创伤后应激障碍症状，以及社会情绪能力的评估等方面的应用。拓展应用于儿童发展领域，尝试探究社会情绪能力的神经生理基础及其发展的生物社会机制。自2012年发表学术论文四十余篇，其中SCI（SSCI）论文四十余篇，CSSCI（CSCD）论文二十余篇。

近期论文

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1. Liuxi Chu, Yan Wu, Cailing Duan, Jin Yang, Haoran Yang, Ying Xie,Quan Zhang, Shan Qiao, Xiaoming Li, Zhiyong Shen, Huihua Deng, Simultaneous quantitation of zidovudine, efavirenz, lopinavir and ritonavir in human hair by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry, J Chromatography B, 2018, 1097-1098, 54-63 (SCI). 2. Yan Wu, Jin Yang, Cailing Duan, Shenghuo Chen, Shan Qiao, Xiaoming Li, Huihua Deng*, Simultaneous determination of antiretroviral drugs in human hair by liquid chromatography-electrospray ionization-tandem mass spectrometry, J Chromatography B, 2018, 1083, 209-221(SCI). 3. Quan Zhang, Zheng Chen, Shenghuo Chen, Tian Yu, Juxia Wang, Weiwen Wang, Huihua Deng*,Correlations of hair level with salivary level in cortisol and cortisone, Life Sciences, 2018,193(1), 57-63. (SCI) 4. Christopher Mwanza, Zheng Chen, Quan Zhang, Weiwen Wang, Huihua Deng*, Simultaneous HPLC-APCI-MS/MS quantification of endogenous cannabinoids and glucocorticoids in hair, J Chromatography B, 2016, 1028, 1-10. (SCI) 5. Tian Yu, Hang Xu, Weiwen Wang, Shifei Li, Zheng Chen, Huihua Deng*, Validation of hair corticosterone in mice and rats as an endogenous biomarker of chronic stress, J Chromatography B, 2015, 1002, 267-276. (SCI) 6. Zheng Chen, Jifeng Li, Guanyi Xu, Jin Yang, Jing Zhang, Huihua Deng*,Simultaneous measurements of cortisol and cortisone in urine and hair for the assessment of 11-hydroxysteroid dehydrogenase activity among methadone maintenance treatment patients with LC-ESI-MS/MS, J. Chromatography B, 2014, 969, 77-84. (SCI) 7. Jing Zhang, Jifeng Li, Youyun Xu, Jin Yang, Zheng Chen, Huihua Deng*, Characteristics of novel hair-based biomarker for the activity assessment of 11β-hydroxysteroid dehydrogenase, Clinica Chimica Acta, 2013, 426, 25-32. (SCI) Zheng Chen, Jifeng Li, Jing Zhang, Xue Xing, Wei Gao, Zuhong Lu, Huihua Deng*，8. Simultaneous determination of hair cortisol, cortisone and DHEAS with liquid chromatography–electrospray ionization-tandem mass spectrometry in negative mode，J. Chromatography B, 2013, 929, 187-194. (SCI) 9. Wei Gao, Tobias Stalder, Paul Foley, Manfred Rauh, Huihua Deng, Clemens Kirschbaum, Quantitative analysis of steroid hormones in human hair using a column-switching LC-APCI-MS/MS assay, J. Chromatography B, 2013, 928, 1-8. (SCI) 10. Xue Xing, Zheng Chen, Jifeng Li, Jing Zhang, Huihua Deng*, Zuhong Lu，Study on dissolution mechanism of cortisol and cortisone from hair matrix with liquid chromatography-tandem mass spectrometry, Clinica Chimica Acta, 2013, 421, 62-72. (SCI) 11. Jifeng Li, Qiaozhen Xie, Wei Gao, Youyun Xu, Shuang Wang, Huihua Deng*, Zuhong Lu,Time course of cortisol loss in hair segments under immersion in hot water,Clinica Chimica Acta, 2012, 413: 434440. (SCI)