个人简介
2004年毕业于中国科技大学生命科学学院,获学士学位;2004年至2009年毕业于中国科技大学生命科学学院神经生物学与生物物理系,获理学博士学位;2009年至2010年为美国国立卫生研究院(NIH)博士后;2010年至2014年为中国科学院苏州纳米技术与纳米仿生研究所副研究员;2014年7月起,受聘为东南大学生命科学研究院研究员,发育与疾病相关基因教育部重点实验室PI。主持或参与承担了国家重点基础研究发展计划(973)、国家自然科学基金、中欧国际合作项目、中国科学院院项目等多项项目。
研究领域
三维微环境对神经干细胞行为调控研究 治疗神经系统损伤或病变依然是目前生物医学界的难点之一。干细胞疗法相关技术的进展给其带来了新的手段,也促进了再生医学和组织工程的蓬勃发展。本实验室为交叉学科实验室,利用细胞生物学、分子生物学、电生理学、材料化学等相关研究手段
近期论文
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Q Song, Z Jiang, N Li, L Liu, M-L Tang*, GS Cheng*. (2014) Anti-inflammatory effects of three dimensional graphene via restricting microglia morphological transformation. Biomaterials (Accepted) (*Co-corresponding author) M-L Tang1, Q Song1, N Li1, Z-Y Jiang, R Huang, et al. (2013) Enhancement of electrical signaling in neural networks on graphene films. Biomaterials, 34:6402-11. (1Equal Contribution) N Li1, Q Zhang1, S Gao, Q Song, R Huang, L Wang, L Liu, J Dai*, M-L Tang*, GS Cheng*. (2013) Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells. Scientific Reports, 3:1604. (*Co-corresponding author) L Qi, N Li, R Huang, Q Song, L Wang, Q Zhang, R Su, T Kong, M-L Tang*, GS Cheng*. (2013) The effects of topographical patterns and sizes on neural stem cell behavior. PLoS ONE, 8:e59002. (*Co-corresponding author) XY Gao1, M-L Tang1, ZF Li, et al., (2013) Streptavidin-conjugated CdSe/ZnS quantum dots impaired synaptic plasticity. J Nanopart Res, 15:1575. (1Equal Contribution) N Li, X Zhang, Q Song, Q Zhang, T Kao, L Liu, G Jin, M-L Tang*, GS Cheng*. (2011) The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates. Biomaterials, 34:6402-11. (*Co-corresponding author) M-L Tang1, Z-F Li1, L Chen, T-R Xing, Y Hu, et al. (2009) The effect of quantum dots on synaptic transmission and plasticity in the hippocampal dentate gyrus area of anesthetized rats. Biomaterials,30(28):4948-55. (1Equal Contribution) M-L Tang, L Luo, D-M Zhu, M Wang, et al. (2009) Muscarinic cholinergic modulation of synaptic transmission and plasticity in rat hippocampus following chronic lead exposure. Naunyn-Schmiedeberg's archives of pharmacology, 379(1):37-45. M-L Tang, T-R Xing, J Zeng, H-L Wang, et al. (2008) Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ Health Perspect, 116(7):915. M-L Tang, M Wang, T-R Xing, J Zeng, H-L Wang, Ruan DY. (2008) Mechanisms of unmodified CdSe quantum dot-induced elevation of cytoplasmic calcium levels in primary cultures of rat hippocampal neurons. Biomaterials, 29(33):4383-4391.